Critical protein prevents DNA damage from persisting through generations
...invaders and labeling them for destruction -- they rearrange their DNA to create various surface receptors that can accurately identify different intruders, a process called V(D)J recombination. Now, in an study published online today in the journal Cell, Rockefeller University Professor Michel Nussenzweig, in...Analysis reveals extent of DNA repair army
...onmental phenomena can cause DNA to break apart or rearrange its nucleotide base pairs in unhealthy ways. If such mutations are left unchecked, they can accumulate over time and lead, ultimately, to cancer or diabetes. Elledge likened the DNA damage response to a command and control center: "It sends out sen...MIT device draws cells close -- but not too close -- together
...ming, it is important for biologists to be able to rearrange cells over time to learn which signals spur change and which don't. In the past, researchers erected chemical "moats" around cells in an attempt to keep them close but separate. Over time, however, cells invariably breech the divide. "They are ver...Scientists identify specific enzymes that make meningitis hard to fight
...retof meningitis' virulence lies in its ability to rearrange its DNA andthus change its external appearance to the body's immune system.Significantly our research has now demonstrated that the ability ofmeningitis to repair its DNA is important for its ability to surviveattack from the body's immune system. Th...Scientists uncover speedometer for crystal growth controlled by biomolecule properties
...to intrigue of how proteins and other biomolecules rearrange local water to affect many different aspects of biological systems. To now show that this restructuring also influences the growth of crystals adds new momentum to this research area. In addition to better understanding how organisms can form biom...Cortical plasticity: it's time to get excited about inhibition
...ct the ability of the visual cortex to plastically rearrange itself following periods of visual deprivation. "Getting our brains to wire up properly requires experience during an early critical period of development, and understanding the mechanisms of this experience-dependent plasticity is critical for...Carnegie Mellon researchers discover key deficiencies in brains of people with autism
..., participants must -- in a set number of moves -- rearrange the positions of three distinctive balls in three suspended pool pockets to match a specified pattern. This requires a person to strategize and plan several moves ahead. The experiment confirmed the authors' previous findings that people with autis...Researchers discover how bacteria sense their environments
...some sort triggers an array of linked receptors to rearrange itself, much like when water freezes, all the water molecules assort themselves into a new structure. Through this reorganization, the bacterium's receptor array amplifies the signal that a specific molecule has been sensed outside the cell. This str...Chromosome rearrangements not as random as believed
...iforms are weak points where the DNA can break and rearrange with DNA from other chromosomes." Chromosome 22 also has palindromic hairpins and cruciform structures, where breaks occur and DNA swaps places with DNA from chromosome 11. Unlike more random, rarer chromosome translocations, the rearrangement betwee...Diabetes complications rooted in faulty cell repair
...the cell, and by adding nitric oxide we're able to rearrange the scaffold," Segal said. "When we rearrange the scaffold, the cells are able to migrate. The benefit of this is that when cells have improved mo...North Shore-LIJ receives FDA approval for new drug application to manufacture PET scan drug
...ays are released as the unstable radioactive atoms rearrange themselves into a stable configuration. Traveling at the speed of light, the gamma rays allow the PET camera to generate a picture of those cells and organs at work. The amount of radiation to which a person is exposed is minimal and compares to that...Enzyme's newly discovered role may make it target for arthritis treatment
... surface of neutrophils. "The way these integrins rearrange and cluster on the cell surface can send a signal back into the cell that modifies the cell's behavior, allowing it to do things like secrete inflammatory factors," Pham explains. "The proteases' ability to affect integrin rearrangement is dependent ...News tips: NASA presentations at Annual 2005 Joint Assembly Meeting
...er 26, 2004 Sumatran Earthquake An earthquake can rearrange the Earth's mass, causing the Earth's rotation and gravitational field to change. In this session, scientists discuss how the Sumatran earthquake of December 26, 2004, may have altered the length-of-day, the Earth's oblateness, and mean position of r...Gene 'archeology' gets easier using Carnegie Mellon University software
...ember genes. Through a series of steps, users can rearrange a massive gene tree with hundreds of branches and no apparent structure so that it becomes a highly organized tree with a distinct root and a clear, concise history of duplications. (See illustration.) "These parsimonious trees give us the simplest ...... observations to explain how anions in salt grains rearrange themselves when the salt liquefies after absorbing water vapor from the surrounding air. Molecular dynamic simulations indicate that the anions migrate and become enriched at the droplet's surface. Other techniques allow scientists to observe the ind...