For young canaries learning their song, freedom in youth gives way to rules in adulthood
...mming is reminiscent of the flexibility of phoneme rearrangement in human speech and is an aspect of vocal prowess in birds that had not been described before," says Fernando Nottebohm, Ph.D., Rockefeller's Dorothea L. Leonhardt Professor and head of the Laboratory of Animal Behavior. Young canaries normally lear...Two UT Southwestern researchers named Howard Hughes Medical Institute investigators
...e and respond to various environmental cues. The rearrangement of the cytoskeleton is very important in neurons and immune cells. The elongation of growing nerves in the right direction is dependent on adjustments in the cytoskeleton. The cytoskeleton of the immune cell can change rapidly, allowing it to squee...JCI table of contents, April 1, 2005
...d with different genetic mutations. In particular, rearrangement of the RET receptor gene, and activation of Ras and B-Raf genes are common events in thyroid cancer, labeling these three as oncogenes (genes that contribute to cancer). In a study appearing online on March 10 in advance of publication in the April 1...Three bacterial genomes found lurking inside recently sequenced fruit fly genomes
...new genes in wAna - as well as a sign of extensive rearrangement between wMel and wAna, indicating that the two strains have diverged significantly since they first infected the two Drosophila species. The two most closely related strains are wAna and wSim, which have nearly identical genomes. wMel and wMoj share ...... new genes in wAna as well as a sign of extensive rearrangement between wMel and wAna, indicating that the two strains have diverged significantly since they first infected the two Drosophila species. The two most closely related strains are wAna and wSim, which have nearly identical genomes. wMel and wMoj share ...Circles of DNA might help predict success of stem cell transplantation
...ecific gene. sjTRECs form during a "mix-and-match" rearrangement of these genes into any one of countless combinations. The rings represent sections of DNA cut out of chromosomes during the mixing and matching of genes that are chosen to build a particular receptor. Each T cell uses the resulting combination of ge...UCLA researchers detail the evolution of quantum dot imaging in the journal Science
...ts, we can follow molecular circuitry, the dynamic rearrangement of the molecular interactions and interactions that re-program cells to gain and lose function in disease - in short, oversee the 'molecular dance' that defines life itself." Two new advances are highlighted in Science, including proof of principle...Cincinnati study of Chernobyl residents uncovers new cause of thyroid cancer
...te a "chimeric oncogene." The two most common gene rearrangement types are called RET/PTC1 and RET/PTC3. Both types...ibility of thyroid follicular cells to chromosomal rearrangement is remarkable." This study represents a major breakthrough in our knowledge of the genetic events in...JCI table of contents, 3 January 2005
...te a "chimeric oncogene." The two most common gene rearrangement types are called RET/PTC1 and RET/PTC3. Both types...ibility of thyroid follicular cells to chromosomal rearrangement is remarkable." This study represents a major breakthrough in our knowledge of the genetic ev...Vollum Institute discovery may unlock human genome
...te on a cancer-causing oncogene that arises when a rearrangement of chromosomes generates an abnormal transcription factor. "If you had a technique that would allow you to take that factor and identify what its targets are, you would understand why that oncogene causes cancer," Goodman said. Another project is exa...Researchers discover a stem-cell switch lurking within leukemias
...oid leukemia, and, MOZ-TIF2 , an abnormal genetic rearrangement that causes acute myeloid leukemia (AML). In their experiments, they introduced these abnormal genes into normal progenitor cells and tested the ability of the resulting cells to self-renew. The researchers found that only MOZ-TIF2 could cause norm...Solving the mechanism of Rett Syndrome
...of additional neighboring chromatin. This dramatic rearrangement in the DLX5/6 gene neighborhood may also involve other disturbances in gene expression. Similar rearrangements, with equally profound effects, may be found among the five dozen other genes targeted in the brain by MeCP2, which are now under active in...UCSD researchers derive lessons about human evolution from chicken genome
...f years." The researchers found a very low rate of rearrangement between chromosomes in the chicken genome--about one-third the rate in the mouse genome, but roughly similar to human evolution. Sequencing of the chicken genome began in March 2003 with funding from the National Human Genome Research Institute (NHRG......e desert regions, which are able to resist genomic rearrangement and fend off infringement by repetitive segments of junk DNA, are home to a surprisingly large fraction of the genome's non-coding regulatory elements. "There are many indications that stable gene deserts represent treasure boxes of multiple g...