Study produces conflicting findings on the use of anti-anemia drug in cancer patients
...hen used within chemotherapy. There are no obvious reasons for this discrepancy." ...Investigational cancer drug targets critical proteins
... temperatures or stored for a long time more good reasons to relax and eat a well- balanced diet, Dr. Yang says. The MCG researchers are now looking at the relationship between the modified hsp90 and breast cancer metastasis and developing antibodies that target hsp90. Heat shock proteins are called m...JCI table of contents: April 12, 2007
...t heart function in humans. However, the molecular reasons why these mutations are associated with impaired heart function have not been determined and many questions remain about how this protein is regulated. For example, in vitro studies have shown that a protein known as calmodulin (CaM) inhibits RyR2 fu...Recent declines in breast cancer mortality greatest in women under 70
...y's lead author. This study did not explore the reasons why breast cancer mortality rates declined less for older women. However, previous studies have suggested that older women are less likely to receive adjuvant therapy for breast cancer. Because older women are under-represented in clinical trials, th...Joslin study indicates insulin receptors play a critical role in promoting islet growth
...ring in younger people, including adolescents. For reasons that are still unknown, islet cells malfunction in people with type 2 diabetes and their bodies are unable to compensate. By investigating the cellular mechanisms that affect islet cell growth and development, Joslin researchers hope to improve the p...New genetic biomarkers could predict coronary heart disease
...ion and inflammation which could be the one of the reasons for telomere shortening and so an early indication of their telomeres starting to shorten could indicate the onset of diabetes and ultimately be a predictor for CAD. In other words, telomere shortening in prediabetics could predict those predisposed ...Natural mechanism for immune suppression paves way for cancer trials
...nt completely eradicate the tumor. One of the main reasons they come back is the tumor already has established an environment which helps protect it, even after chemotherapy," Dr. Mellor says. Although the IDO inhibitor will first be studied alone, he believes it will become part of the treatment cocktails...No need to thank dinosaur-killing asteroid for mammalian success
...e epoch, about 56 to 34 million years ago, but the reasons are unclear. "Thats one of the next big questions," Gittleman said. "Now that we have this complete tree, we can examine what ecological characteristics correlate with the upturn." Gittleman points out that flowering plants first appeared during...Genomics throws species definition in question for microbes
... genetic cohesiveness expected of them. For these reasons and others it has become clear that the species classification framework in use today is not capable of fully portraying and organizing microbial diversity." The report contains an in-depth review of the myriad issues and conflicts involved in the...Blood's clotting cells harbor 'ticking time bombs,' finding may help extend blood supply
...the cancer-fighting agents, Huang explained. For reasons that arent yet entirely clear, donated platelets must be stored at room temperatures, the researchers said. When kept under colder conditions, transfused platelets are recognized as foreign by a recipients immune system and quickly cleared from the b...MIT biologists solve vitamin puzzle
...hway, to form the vitamin. One of several possible reasons why it took so long to identify BluB is that some bacteria lacking the enzyme can form DMB through an alternate pathway, Walker said. One of the most unusual aspects of BluB-catalyzed synthesis is its cannibalization of a cofactor derived from ano...Study reveals how some molecules inhibit growth of lung cancer cells
...EGFR mutations than others, although the molecular reasons for this are unclear. By developing a better understanding of the effect of the mutations on inhibitor binding at a structural level, it may be possible to develop more effective therapies. In the current study, Eck and his colleagues analyzed the ...Blood tests may be possible for mental health conditions
... they have panic disorder. This is just one of the reasons that it would be helpful to have a blood test for panic disorder," Philibert said. A blood test for commercial use is now being developed by the UI, which raises larger questions about how information revealed by such tests will be used. The issue ...Joslin researchers discover a surprising culprit in the search for causes of diabetic birth defects
...are the cause of these defects. This is one of the reasons why women with diabetes who are planning a pregnancy are encouraged to have their blood glucose levels under good control prior to conception. The Joslin researchers also have shown that the damage occurs because the extra glucose in the mother's blo...National panel led by LSU Chancellor releases report on Corps of Engineers
... idea on paper and was done for the right economic reasons at the time, but it eventually resulted in saltwater intrusion that damaged the adjacent wetlands." "Here in Louisiana, we appreciate how water resource planning requires national priorities by Congress in public work projects that will protect cri...Studies force new view on biology of flavonoids
...compounds may indeed benefit human health, but for reasons that are quite different the body sees them as foreign compounds, researchers say, and through different mechanisms, they could play a role in preventing cancer or heart disease. Based on this new view of how flavonoids work, a relatively modest i...Joslin study reveals how a specific fat type can protect against weight gain and diabetes
...reviously unrecognized and is certainly one of the reasons for the differences in energy expenditure between strains of mice. Now we need to see if the same is true for humans and if this could account for why some people gain weight easily and others seem to be protected against weight gain and metabolic sy...Size matters if you're a rodent
...ted in either primates or bats." Understanding the reasons for these differences will require a better understanding of the precise mechanisms through which male rodents benefit from longer penises, something which comparative data alone cannot address. Overall, the rodent with the longest penis bone rela...Is it ethical for scientists to do research abroad that would be forbidden at home?
...ging the ethics of such research. There are many reasons for scientists to undertake research abroad, says Professor Skene, including gaining access to more diverse research facilities and participants in research, or acquiring kudos, academic advancement, or commercial benefits from an enhanced internatio...Magic beans -- Anti-obesity soya could help prevent diabetes
...lesterol lowering capabilities; this is one of the reasons why frozen food manufacturer Birds Eye has added the beans to its range. However, a team of Korean researchers has shown that black soya may be even more potent in rats, and also prevents weight gain (Journal of the Science of Food and Agriculture, F...