Tag: "receptors" at biology news
Commandeering cellular machinery: recognition mechanism to detect small molecules
... this cellular protein machinery known as nuclear receptors
the technique could also lead to new methods for ...eutical compounds. "We are hijacking these nuclear receptors
for a new set of purposes," explained Donald Doyle, assistant professor in the School of Chemistry a...
Columbia University scientist wins 2004 Nobel Prize
...e than 1,000 different genes that encode olfactory receptors
in the nose that detect odors and olfaction. This...nect the brain to the outside world. In the nose, receptors
on the neurons pick up odors from the environment and send that information directly to the olfactor...
HHMI researchers Richard Axel and Linda Buck win 2004 Nobel Prize
...uivalent number of olfactory receptor types. These receptors
are located on the olfactory receptor cells, which...scovered a family of genes that encode the odorant receptors
of the olfactory epithelium, a patch of cells on the wall of the nasal cavity. The olfactory epithel...
Putting physiology into the Nobel Prize: 2004 marks 100th anniversary of Pavlov's award
...ery in 1991 of a large multigene family of odorant receptors
that several specific questions (about the nature of smell) could be answered."] Three years after the inception of the Nobel Prizes in 1901, Ivan Pavlov still the world's most famous physiologist won the award "for physiology," making the 2004 a...
Researchers provide road map for generating B cells from stem cells
..., stage 2. They trigger the expression of certain receptors
on the cell surface, such as Flk2 followed by IL-7... denying it." At each stage, different markers or receptors
appear on the cell surface, which helps the researchers monitor a cell's progress and enables the ce...
Experimental drug prevents vaginal simian HIV transmission in monkeys Science study says
...e concerned, HIV) from latching on to cell-surface receptors
called CCR5. Although in some settings, HIV may use other receptors
to get into cells, the success of PSC-RANTES against SHIV in these experiments suggests that CCR5-in...
Time-lapse movies show brain cells move like a two-stroke engine
...orks will lead us to novel classes of cell surface receptors
that regulate migration, and thereby the formation of cortical areas of the brain," says Hatten....
Ancient Chinese folk remedy packs anti-cancer punch
...ood, and is transported into cells via transferrin receptors
on a cell's surface. Iron-hungry cancer c...ells typically have significantly more transferrin receptors
on their surface than normal cells, which allows them to take in more of the iron-carrying protein. ...
A new culprit in depression?
...d fibroblast growth factors (FGFs), and two of the receptors
that bind to them, were significantly lower among ...ants before their deaths had levels of FGF and FGF receptors
that were closer to normal. The results are published online this week in the early edition of the ...
Scientists identify new cause of obesity
...vide a whole new way of thinking about how hormone receptors
could cause disease, and suggest different types o...light, chemicals or hormones, and mutations in the receptors
are implicated in many diseases. The new research provides the first evidence of an essential role f...
Zebrafish may offer researchers powerful new tool for studying innate immunity
..., researchers have sequenced all 36 genes of novel receptors
that appear to play a critical role in the innate ...e most genetically complex system of innate immune receptors
thus far described,"said principal investigator Gary Litman, PhD, Hines professor of pediatrics who ...
Early life stress can inhibit development of brain-cell communication zones, UCI study finds
...he researchers used a selective blocker of the CRH receptors
and were able to reverse the actions of CRH, which led to well-developed brain-cell dendrites. But Baram warns that much more research is needed to see if this blocker can work in animal models or in humans. The Baram group is continuing its study to...
International human genome sequencing consortium describes finished human genome sequence
...explain why humans have fewer functional olfactory receptors
and, consequently, a poorer sense of smell than rodents. The molecular biology of the sense of smell was just recognized by the awarding of a Nobel Prize in Physiology or Medicine to Richard Axel and Linda B. Buck. Next, the researchers aligned the 3...
Are yeast cells bringing us a step closer in treating obesity?
...holic University of Leuven have shown clearly that receptors
in yeast cells detect and react to nutrients in th...lls. Because about 40% of today's medicines act on receptors
in our cells, this research opens new possibilities for the treatment of metabolic disorders such as...
Deciphering an autism mystery
...utes to autism and that autistic people have fewer receptors
for the brain messenger acetylcholine, as well as ...smitters are small molecules that bind at specific receptors
on neurons to send either inhibitory or excitatory signals. Communication throughout the brain depen...
Yerkes researchers to present array of new data at Society for Neuroscience Meeting
...cocaine addiction regulates metabotropic glutamate receptors
in the nucleus accumbens, a key structure in the brain's reward pathway that mediates cocaine addiction. The data will help researchers further understand the neurochemical changes that underlie addiction and drug abuse. (2 pm 3 pm) Dr. Young and ...
Novartis receives European marketing authorization for Emselex(R)
...ls bladder contraction while sparing the M1 and M2 receptors
believed to be involved in central nervous system (CNS) and cardiovascular (CV) function, respectively. (1) Emselex has been shown to reduce the number of weekly incontinence episodes by up to 77% (2) versus placebo. Additional clinical trials have...
Scientists closing in on nerve proteins' contributions to memory and hearing loss
...rmal role, PSD-95 provides a support structure for receptors
on the receiving end of a synapse. The protein has...zheimer's patients. "If you have too many receptors
at a synapse, the nerve cell gets overstimulated and dies," Bao notes. "Too few, and the signal can'...
Stress impairs thinking via mania-linked enzyme
...nsitive messenger chemical norepinephrine binds to receptors
on cell membranes in the prefrontal cortex, it act...t bipolar disorder as well as schizophrenia, block receptors
in the brain that activate PKC....
UO study is first to link histamine receptors to heat stress
...dent's research is the first to identify histamine receptors
as contributing to increased blood flow during hea...re to prolonged heat waves. "These are the same receptors
that are involved in seasonal allergies for which people take antihistamines," says Wong, who is the...
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