New source for heart bypass replacement blood vessels: Fibrin-based TEVs
...y will also seek to make the matrix stronger using recombinant DNA techniques and "engineer vessels from bone marrow-derived stem cells to provide a source of autologous cells for transplantation, and therefore avoid the use of native vessels as a cell source," Andreadis noted....UCSD researchers find effective treatment for unusual fever syndrom caused by cold exposure
...tal cold challenge, the researchers administered a recombinant IL-1 receptor antagonist, a drug called anakinra, which inhibits the action of IL-1 and thus prevents acute inflammation, fever and flu-like symptoms. The treatment prior to cold exposure prevented the clinical and laboratory manifestations of the d...New gene therapy promising for treating Fabry disease
... course of treatment requiring weekly or bi-weekly recombinant enzyme infusions done in a hospital. Corrective gene therapy, if approved for human use, would possibly translate to a one-time treatment....Northwestern and Chicago Botanic Garden join forces to train botanists
... nucleic acid and chromosome structure; and master recombinant DNA technology and gene cloning. Upon graduation, the plants scientists will go on to work in the nation's botanical gardens, for the government and non-government organizations, as teachers in high schools or junior colleges or as students in doct...Study reveals developing countries with recipe for thriving health biotech industries
...ort their own biotech vaccines, Egypt manufactures recombinant insulin, and South Africa is developing a novel vaccine for HIV/AIDS. Health biotechnology is no longer the sole preserve of high-level research institutions of North America and Europe, according to a ground-breaking three-year study ...Chicken genome analysis will benefit human health and agriculture
...e birds lack. She also provided DNA used to create recombinant DNA clone maps of the chicken genome. Those maps provided the framework for the much more detailed genome sequence assembly. "Chickens and humans are, in some cases, infected by the same viruses, bacteria and parasites," said Dodgson, one of the ...Tips from the Journals of the American Society for Microbiology
...icacy and immunogenicity of replication-defective, recombinant glycoprotein, and DNA vaccines for herpes simplex virus 2 infections in mice and guinea pigs. Journal of Virology, 79. 1: 410-418.) ************************************* Houseflies May Contract E.coli from Cattle Houseflies on cattle farms may con...Novel asthma study shows multiple genetic input required; single-gene solution shot down
...th elevated nave AHR in the phenotypically derived recombinant congenic line." However, according to Beier, "we were fortunate that the analytical approach we were using allowed us to check not just for association of a single locus, but for the possibility that there might be coordination or cooperation between...Startling results from new biomedical research international conference
...lots. The company spent considerable sums in using recombinant DNA technology to bring the product to the brink of the marketplace and applied for a protective patent. But despite the company's outlay and effort, this was refused because several other companies had also been racing to develop the drug. Consequen...AAAS honors recombinant DNA advisory committee at NIH, citing 30 years of leadership
...at has allowed society to proceed responsibly with recombinant DNA research" and gene therapy. The prestigious 20...scientific, medical, ethical and social aspects of recombinant DNA research. Such research, which involves combining natural or synthetic genetic segments to form ...Children's Hospital & Research Ctr. at Oakland's DNA library helps to map the sex chromosome
...rig's Disease," said Dr. de Jong. The hospital's recombinant DNA library has more than 20 million DNA samples that are used in research programs around the world....Aeras and UCLA announce license deal for new TB vaccine
...he disease. The new tuberculosis vaccine, a live recombinant vaccine named rBCG30, was developed in the course of research at UCLA's David Geffen School of Medicine by Dr. Marcus Horwitz and his team. The rBCG30 vaccine overexpresses the major protein secreted by the TB organism and uses the current TB vaccin...Protein prevents detrimental immune effects of bacterial sepsis
...in 1 knockout mice were given small doses of human recombinant annexin 1 in the first 24 hours following LPS treatment, survival increased to 60%. These results, obtained in the lab of Dr. Mauro Perretti, highlight the delicate balance between the "pro-inflammatory/detrimental vs. anti-inflammatory/protective ...Tetanus toxin found to have therapeutic properties
...ers have also been able to show that toxin and its recombinant fragment, carboxy terminal, the harmless fragment, strengthens the neural cells and protects them from external aggressions. This means it has a neuroprotective effect that prevents the death of the neurons when they are faced with aggressive situati...Fragment of yellow fever virus may hold key to safer vaccine
...acturers design a more consistent vaccine based on recombinant genetic technology, without the potential side effects from variations of the weakened virus strain now grown in fertilized chicken eggs....Tips from the Journals of the American Society for Microbiology
...hen infected with the virus and immunized with the recombinant vaccine. All mice receiving the vaccine developed antibodies and survived an otherwise lethal challenge with the influenza and parainfluenza viruses. "This live bivalent vaccine has obvious advantages over combination vaccines, and its method of ...UF researchers test drug that could cut orthodontic treatment time in half
... first study to use a naturally occurring hormone, recombinant human relaxin, to biochemically augment tooth movement and retention." Relaxin is best known as the hormone that helps women's pelvic ligaments stretch in preparation for giving birth. It does this by softening collagen and elastin in the tissues, lo...Interim data suggest major response with Aranesp(R) in anemic patients with MDS
...respond," added Gabrilove. "There are currently no recombinant erythropoietic products approved by the FDA for th...ople older than 60. About Aranesp Aranesp is a recombinant erythropoietic protein (a protein that stimulates production of oxygen-carrying red blood cells). Am...Stephen P Goff awarded inaugural Retrovirology Prize
...functional copy of a retroviral genome, and to use recombinant DNA methods to study viral replication. Over the last two decades Dr. Goff has developed and exploited the Moloney murine leukemia virus as a genetic system. One of his most important results was the definition of the functional domains of the viral......Increased vaccine efficacy against tuberculosis of recombinant Mycobacterium bovis bacille Calmette-Gurin mutants that secrete listeriolysin AUTHOR CONTACT: Stefan Kaufmann Max Planck Institute, Berlin, Germany Phone: 49-30-28460-500/-506; E-mail: kaufmann@mpiib-berlin.mpg.de View the PDF of this article at...