Veterinary scientists explore poultry virus as cancer killer
... Reverse genetics is the process of generating a recombinant virus from cloned complimentary DNA (cDNA) copy of...ains Subbiah. Through the reverse genetics system, recombinant viruses can be designed to have specific properties that make them attractive as biotechnological to...NIH awards VBI, Mayo Clinic $2.4M to study chronic rhinosinusitis
...mendar Rathore. The VBI team will produce a set of recombinant fungal proteins that will be used to dissect the different molecular steps involved in the development and progression of CRS. The VBI researchers will also create a series of fungal knockout mutants for specific genes that will be evaluated in in vi...Ronald Cape to receive 2007 Biotechnology Heritage Award
...ape saw the potential of biotechnology even before recombinant DNA. He helped to create a new kind of company and with it launched the creation of a whole new industry." About Ronald E. Cape Cape, a partner at PureTech Ventures in Boston , cofounded Cetus in 1971 and served as its chairman for 20 years and ...Spotlight on liver disease: Improving today's treatments
...ts function. Previous studies have suggested that recombinant factor Vlla (rFVlla), an agent used to control bleeding, may reduce the number of failures and improve 24-hour bleeding control in Child-Pugh B and C-classified cirrhotic patients with variceal bleeding. Cirrhotic patients classified in class B or C...Virus widely used in gene therapy research yields important clues to genomic instability
...of genomic instability in sporadic cancers using a recombinant adeno-associated virus, the same virus that many researchers around the world use for gene therapy experiments. The results of their work are being presented at the 10th annual meeting of the American Society of Gene Therapy, which is being held May ...JCI table of contents -- June 1, 2007
...uld be blocked and reversed by the addition of the recombinant globular adiponectin domain (gAd). Importantly, prior administration of gAd was also shown to protect healthy mice against the induction of leukocyte-endothelium interactions. The study demonstrates a clear role for normal levels of adiponectin in th...Gene therapy delivery of nerve growth factors reverses erectile dysfunction in animal model
...plex virus (HSV). They then injected either of the recombinant viruses into the damaged cavernous nerve of rats. GDNF is an important nerve growth promoter and has been shown in other studies to contribute to survival and regeneration of penile nerves. Neurturin also is a nerve growth factor closely related to G...JCI table of contents: June 14, 2007
...ese effects were reversed by the administration of recombinant TRAIL (rTRAIL). Importantly, the application of rTRAIL to mice with intact TRAIL and meningitis also decreased inflammation and neuronal cell death. Finally, the authors observed that human patients with bacterial meningitis showed increased synthesi...Hot on the TRAIL of controlling inflammation in bacterial meningitis
...ese effects were reversed by the administration of recombinant TRAIL (rTRAIL). Importantly, the application of rTRAIL to mice with intact TRAIL and meningitis also decreased inflammation and neuronal cell death. Finally, the authors observed that human patients with bacterial meningitis showed increased synthesi...Personalized approach to ovarian stimulation achieves high ART pregnancy rates
...ent doses of a follicle stimulating hormone called recombinant human follicle stimulating hormone, filled by mass (r-hFSH FbM or GONAL-f FbM). [2] The doses, measured in international units (IU), were 75, 112.5, 150, 187.5 and 225. The women were treated for an average of 11 days. Oocytes were retrieved from 8...JCI Table of Contents -- July 2, 2007
...rvard Medical School show that administration of a recombinant form of the protein hemojuvelin (HJV) to mice was ...at injection into mice over a period of weeks of a recombinant form of HJV binds bone morphogenetic proteins (BMPs), acts as an antagonist of BMP, thereby decreasi...Fedoroff, of Penn State, to receive National Medal of Science
...d discussed the many issues surrounding the use of recombinant DNA techniques. More recently, she has been active in public discussions surrounding the introduction of genetically modified crop plants. She co-authored a book with science writer Nancy Marie Brown titled "Mendel in the Kitchen: A Scientist's Vie...