Putting an old drug to a new use
... humans. Our body needs most of its iron to make red blood cells. A lack of the metal can lead to dangerous anemias, but also too much iron can be detrimental as iron promotes the formation of toxic radicals leading to tissue damage. Iron overload is the consequence of one of the most common genetic di...Yale biologists 'trick' viruses into extinction
...ace, but no nucleus for virus reproduction. Mature red blood cells could fill the bill, because they lack a nucleus and could be engineered as sink habitats that greatly outnumber the T-cell source habitats in the body." ...Grape expectations for healthier wine
... wines. Antioxidants, natural compounds found in red wine, chocolate, coffee and many fruits, are believed to help prevent a variety of diseases including cancer and neurodegeneration....Folate and B12 may influence cognition in seniors
...y reduced amounts of hemoglobin in oxygen-carrying red blood cells, or by a deficiency in the number or volume of such cells. "For seniors, low vitamin B12 status and high serum folate was the worst combination," says Morris. "Specifically, anemia and cognitive impairment were observed nearly five tim...Shedding new light on proteorhodopsin
...green light, but stopped when they were exposed to red light." In the absence of the azide respiratory poison, green light had no effect on the flagellar motors of these proteorhodopsin-equipped E. coli. By measuring the pmf of individual illuminated cells under different concentrations of azide or va...New analyses reinforce efficacy of Remicade in treatment of severe psoriasis
...red by the NAPSI scoring system, including lunular red spots and splinter hemorrhages (small areas of ble...leukonychia (discoloration), nail plate crumbling, red spots in the lunula (crescent-shaped area at bottom of nail), onycholysis (separation of nail from n...... as MC1R, this one which gives people pale skin, red hair and freckles and therefore makes them more susceptible to sun damage." But it isn't simply genetic. For example, in Australia up to 11 per cent of melanoma patients report an earlier family history of the disease, compared to just one per cent...Adult stem cells to repair hearts damaged by severe coronary artery disease investigated
...ate specific blood components such as platelets or red blood cells, to collect from the subjects bloodstream, an enriched preparation of cells that contain CD34+ stem cells. When this process, known as apheresis, is complete, technologists further process the collected stem cells with Baxters ISOLEX 300i...'Electric' fish shed light on ways the brain directs movement
...stems, in the same way that a driver approaching a red light knows he has to apply the brakes ahead of time to avoid overshooting and ending up in the middle of a busy intersection," Fortune said. "Your brain has to do this all the time when controlling movement because your body and limbs, like a car, h...JDRF-funded researchers discover protein that causes blood vessel leakage and swelling in eyes
...se 1, or CA-1, an enzyme that is normally found in red blood cells. "We suspected that high levels of this protein in the vitreous fluid might cause problems," says Dr. Feener. "When we tested it in the vitreous of rodents, we found a marked increase in blood vessel leakage, which is a fundamental proce...Human preference for other species could determine whether they survive
...e effect to that of a man in a tuxedo pinning on a red carnation. Unlike some other types of animals, human preference for particular penguin species does not seem to be driven by a "cuteness" factor. The four books Stokes examined were published in the last decade and were aimed at the popular adult ...Simulating human metabolism to find new diets to new drugs
...in silico any type of cell, from a heart cell to a red blood cell, with its particular complement of metabolic enzymes, and adjust their genetic or other properties to compute the cell's behavior. "We can analyze abnormal metabolism at the root cause of diseases such as hemolytic anemia, which can resu...Joslin discovers protein that causes blood vessel leakage and swelling with diabetic retinopathy
...CA-1. "This is an enzyme that is normally found in red blood cells; however we suspected that high levels of this protein in the vitreous fluid might cause problems," said Dr. Feener. "When we tested it in the vitreous of rodents, we found a marked increase in blood vessel leakage, which is a fundamental......es? Earlier research showed beta spectrin makes red blood cells flexible so they don't burst, and that people with a beta spectrin mutation suffer a form of anemia. The Utah biologists showed in nematode worms ? frequently used as genetic stand-ins for humans ? that loss of beta spectrin leaves neur...DNA gets new twist: Carnegie Mellon scientists develop unique 'DNA nanotags'
...eins. Found in certain types of algae, such as the red and blue algae in fresh and marine waters, these p...e nanostructure. The second dye then emits orange, red or even infrared light. Changing the light-harvesting dyes allows even more variation in the fluores...Together, biological membranes prevail
...ated membrane fusion. In FRET, a pair of green and red dyes is used where only the green dye can directly be excited by a laser. The red dye lights up if some of the energy from the green dye hops over to the red dye which becomes increa...The time it takes to reassemble the world
...ngly designed pairs of simple imagesfor example, a red vertical stripe pattern or a green horizontal patt...y which image the vertical or horizontal one was red or green. In other words, the brain could "see both form and color but could not see how they were c...Cloudy apple juice four times healthier than clear
...ls. Polyophenols are also found in dark chocolate, red wine and are widely reported to have anti-caner activity. The research published this month in the SCI's Journal of the Science of Food and Agriculture (DOI: 10.1002/jsfa.2707). Lucy Ede, Head of Products at the juice company Innocent, said they alr...Researchers discover surprising drug that blocks malaria
...ers have discovered how malaria parasites persuade red blood cells to engulf them -- and how to block the...ing parasites. The malaria marauders hack into the red cell's signaling system and steal the molecular equivalent of its password to spring open the door t...Scientists sequence genome of parasite responsible for common sexually transmitted infection
...d begins to ingest the cells, as well as white and red blood cells, causing direct damage to the urinary and vaginal tissues and resulting in inflammation. T. vaginalis also consumes bacteria that may be present in the urinary and genital areas, including the bacteria necessary for maintaining a normal h...