32 new grants made for innovative technology R&D
... and fix design errors after fabrication, enabling reduced design cycle time, bypassing manufacturing defects...t production at significantly increased output and reduced cost. Receptor Logic, Ltd. (Amarillo, Texas) TCR Mimics: A New Class of Antibodies Against HL...Good news: As you age, leg blood vessels adapt so you can still exercise without fainting
...er men could be a compensatory mechanism for their reduced level of cardiac output during exercise," they rep...stricted more, perhaps as a compensation for their reduced level of cardiac output. This indicates that the balance between vasodilation and vasoconstriction ...Protein energy profiles offer clues about amyloids
...a mountain range, looking for low-lying valleys -- reduced energy states where the protein is most likely to become sidetracked before it can finish folding into its proper shape. Ultimately, Clementi hopes the technique will be refined and used to catalog the folding energies of proteins that have already b...September/October 2004 Annals of Family Medicine tip sheet
...ents about reducing their alcohol use successfully reduced high-risk drinking among those patients as well as the number of motor vehicle crashes, arrests for substance or liquor violations and emergency room visits. Analyzing the results from 226 young adults between the ages of 18 and 30 who participated i...Low dose radiation evades cancer cells' protective 'radar'
...r doses. In the low-dose group, ATM activation was reduced by 40 to 50 percent. The researchers proved ATM inactivation was the culprit since low-dose irradiated cells fared better after ATM was reactivated with chloroqine, best known as a treatment for malaria. "Tricking cancer cells into ignoring the damag...Muscle-building hand-grips aid systolic blood pressure, carotid AD, endothelial function
...ers also noted that following training there was a reduced reactive hyperemic flow (blood flow after cuff deflation). Although the amount of blood flowing through the artery was less than before training, the artery still dilated more. This suggests a heightened vasoactive sensitivity to the reactive hyperem...Sedentary overweight people get insulin boost from short term exercise; CVD risks trend down
... training in negative energy balance significantly reduced insulin resistance," however, replacing energy lost while exercising "resulted in no change in insulin action." Black said the findings "suggest that subtle changes in energy balance that precede measurable fat loss play a key role in mediat...US Agency for International Development awards $34 million to Virginia Tech
... countries involved through increased farm income, reduced pesticide use, greater involvement of women in Int...irginia and the United States will benefit through reduced pesticide residues on imported fruits and vegetables, expanded demand for our export products as inc...Channel protein converts vibrations to electrical signal
... the developing ear, and found that this, too, was reduced when TRPA1 levels were low. Given the evidence that TRPA1 plays an integral role in the conversion of a mechanical stimulus to an impulse that the brain can interpret, Corey is eager to determine whether defects in TRPA1 might play a role in inherit...Anti-cholesterol drug treats Alzheimer's disease in mice
...s found that treatment of the normal mice markedly reduced the levels of the storage form of cholesterol in t...ains. And in the transgenic animals, the treatment reduced the accumulation of amyloid plaque by 88%99% percent and reduced the storage form of cholesterol by ...Research into the sense of touch in worms wins Eppendorf/Science Prize
.... Humans rely heavily on their sense of touch, and reduced touch sensation is common in people with diabetes and is a leading factor in lower-extremity amputation. However, scientists know very little about the molecular basis of touch, mainly because studying the sensory nerves that detect touch are deeply ...Mechanism discovered for muscle wasting seen in diabetes, AIDS and other diseases
... birth, but as they matured, their body weight was reduced due to decreases in skeletal muscle mass. Their muscle fibers were also smaller than those of their non-genetically altered littermates. On the other hand, the MISR mice were normal in terms of appearance, body weight, and individual muscle weight an...Perceptual decision-making hub pinpointed in human brain
...rd to discern images evoke a relatively slower and reduced response in the decision-making area, as it mulls ...in the brain's frontal cortex showing the telltale reduced activity during hard trials that coincided with activity in temporal lobe visual processing circuits...Researchers find protein that makes long-term memory possible
...shown that the brains of Alzheimer's patients have reduced levels of mBDNF or plasmin. ...Using fruitflies to examine alcohol tolerance
...erves as the fly version of norepinephrine showed reduced rapid tolerance but unchanged chronic tolerance. In sum, two different lines of experiments provide pharmacological and genetic support for the idea that rapid and chronic tolerance may utilize at least partially distinct pathways in flies." "Th...The long road to a promising malaria vaccine started at NYU School of Medicine
...re than 2,000 children in Mozambique, the vaccine reduced life-threatening attacks of malaria by 58 percent, and reduced milder forms of the disease by 30 percent. The study is published in the October 16, 2004, issue of ...UCSD medical researchers use brain cell transplants to correct muscle spasms after aneurysm surgery
...f Medicine. Ischemic spinal cord injury, caused by reduced blood flow to the spinal cord, occurs in 20 to 40 percent of the several hundred patients each year in the U.S. who undergo surgery to repair an aneurysm, or sac-like widening of the aorta, the main artery that leaves the heart. A subpopulation of pa...Gene-altered mouse is model for rare autoimmune syndrome
... all the characteristics of the disease, including reduced tear and saliva secretion and infiltration of lymphocytes into their tear and salivary glands. The animals also showed production of the antibodies that indicated the immune system was activated to attack the animals' own tissues. Also, the ...Passage of GMO ban in San Luis Obispo would encourage use of harsh pesticides
...ume. Similarly, soybeans have been engineered with reduced allergens, which will lead to safer soy-based infant formula and other soy food products. Much lower levels of mycotoxins, known potential cancer-causing agents, have been found in lines of genetically engineered corn, compared to co......ofilm cells promoted tolerance to the chromium and reduced its toxicity level. Finally, when the cells made the transition from the planktonic state to the biofilm state, the scientists observed changes in the concentrations of many transition metals required for bacterial life. These results suggest that X...