New target for obesity and related metabolic disorders
...s suggest this prototypical compound might lead to reductions in body weight that can match the effects of sibutramine," added Jim McCormack, Vice President of Research for Prosidion Ltd. Sibutramine (Meridia) is a marketed drug, although its use has been limited by its potential for side effects, including hyp...Some heart patients vulnerable to mental stress
...We believe the phenomenon of mental stress-induced reductions in blood flow to the heart is much more common tha...ary artery disease who experience exercise-related reductions in blood flow to the heart respond similarly to mental stress. These bouts often produce no symptoms...Pesticides in the nation's streams and ground water
...ions of these compounds in fish declined following reductions in their use during the 1960s and elimination of all uses in the 1970s and 1980s, and continue to slowly decline. Just as notable as the declines, however, is the finding that these persistent organochlorine pesticides still occur at levels greater t...The rising tide of ocean plagues: How humans are changing the dynamics of disease
...ee a decline in parasite populations. In the end, reductions in parasite populations may be an equally important indicator of ecosystem malfunction as the more publicly alarming increases in disease. "Often, we don't realize we miss infectious diseases until we have invasive species that become pests without ...Study finds no safe level for ozone
...nvironmental Studies. "This indicates that further reductions in ozone pollution would benefit public health, even in areas that meet regulatory requirements." Researchers found that even for days that currently meet the EPA limit for an acceptable level of ozone--80 parts per billion for an eight-hour period-...Early California: A killing field
...ound. Species with the most significant population reductions were those most attractive to hunters: large birds...causes, such as changes in prehistoric climate and reductions in bird habitat. For example, the decline in cormorants might have been caused by the climate disrup...U of MN researchers identify new cord blood stem cell
... with experimental strokes resulted in significant reductions in the size of brain lesion, and improved these animals' use of their limbs. Some of the transplanted stem cells developed into "neuron-like" cells that are typically found in the brain. In addition, the transplanted cells also induced an unanticip...... fox introductions extended well beyond the direct reductions of bird populations. We have clear evidence that foxes influence the terrestrial plant community and ecosystem dynamics through one particular route," state the researchers in their study. The experiment The Aleutian archipelago has over 450 isla...Recycling of aeronautics components
...an important increase in this percentage, enabling reductions in both weight and cost of aircraft, enhanced safety conditions and reduced environmental impact. Considering that the average life of a plane is about 20 years and that parts made from composite materials are not repaired but replaced, the aeronauti...Storing carbon to combat global warming may cause other environmental problems, study suggests
...ations of all ages resulted in average stream flow reductions of 38 percent, with losses increasing as the trees aged. Moreover, "13 percent of streams dried up completely for at least one year," the study said. Overall, about 20 percent more of the water provided by precipitation was removed by current tree fa...Science's Breakthrough of the Year: Watching evolution in action
...of the most intense tropical cyclones to continued reductions in ice cover in the Arctic Ocean and altered bird migratory patterns, scientific evidence for climate change built up in 2005 and non-scientists seem to have listened. Cell Signaling Steps Up: Dynamic views of how cells respond to the chemical and e...Some good news for the world's poor
...se China had already achieved rapid and very large reductions in poverty before 1999. "But the overall total reduction in rural poor through rice research in China has been much larger than in India," if looked at over the past 20 years instead of just 1999. "Ending poverty among the world's poor is an enormous...Pollination networks key to ecosystem sustainability
...nd that such losses may ultimately trigger further reductions in biodiversity, possibly reverberating through the food chain. With as many as 70% of plant species dependent on animal pollinators and at least 82 mammalian pollinator species and 103 bird pollinator species considered threatened or extinct, this i...Interim Aranesp data suggest major response in anemic patients with MDS
...crease exceeds 1.0 g/dL in any 2-week period, dose reductions are recommended. In a study with another erythropoietic product, where the target Hb was 12 - 14 g/dL, an increased incidence of thrombotic events, disease progression, and mortality was seen. Pure red cell aplasia (PRCA) has been observed in patie...New Phase 3 data show potential benefits of Aranesp dosed every three weeks for CIA
...crease exceeds 1.0 g/dL in any 2-week period, dose reductions are recommended. In a study with another erythropoietic product, where the target Hb was 12 to 14 g/dL, an increased incidence of thrombotic events, disease progression, and mortality was seen. Pure red cell aplasia (PRCA) has been observed in pati...Overfishing in inland waters reduces biodiversity and threatens health
... fish populations respond to fishing pressure with reductions in mean size at maturation. Allan and colleagues identify two main types of overfishing. One leads to marked declines in catch per unit effort and size of individuals captured. The second type is characterized by sequential declines of species and de...'Go Fishing' no game for inland waters worldwide
...e world every year. Research has demonstrated that reductions of some of these species can profoundly affect productivity and other ecological attributes of freshwater ecosystems, Winemiller added. "Managing fisheries today is not limited to just satisfying the commercial fishing industry, but must accommodate...Oil mist reduces airborne hazards in concentrated swine feeding operation
...n a mid-Atlantic swine facility. It found ten-fold reductions in the amounts of dust and bacteria in a barn where the spray was used compared with an identical barn where no spray was used. In contrast, however, the oil spray did not impact levels of ammonia, another pollutant generated from CAFO facilities. "F...Nutrient pollution causes a long-term effect on Chesapeake Bay ecosystem
...uxent Rivers, where significant nutrient pollution reductions have occurred, complex ecological relationships have not been fully restored. For example, while algae blooms decreased in the Patuxent River with decreasing nutrients in the last fifteen years, the bottom water dissolved oxygen levels are still ver......y explored more open areas than normal mice. Thus, reductions in innate fear behaviors, such as avoiding open spaces as opposed to "safer" areas with less exposure, correlated with the absence of Stathmin. Shumyatsky explained that the difference between the earlier research paper and the current one is that th...