News tips from The Journal of Neuroscience
... H. Pate Skene, and Joel M. Levine Axons trying to regenerate after spinal cord injury face a major obstacle in the form of the glial scar. It's not only figuring out what makes axons grow, but also avoiding things that may inhibit growth, such as myelin-associated growth inhibitors, semaphorins, and chondroiti...DARPA grant supports research toward realizing tissue regeneration
...r systems that allow certain animals to completely regenerate lost tissue. The ultimate goal of the research is ...during embryonic development mammals and birds can regenerate such diverse tissues and structures as their skin and spinal cord. However, humans can't perform the...New research demonstrates bone-marrow derived stem cells can reverse genetic kidney disease
... discovery that bone-marrow derived stem cells can regenerate damaged renal cells in an animal model of Alport syndrome provides a potential new strategy for managing this inherited kidney disease and offers the first example of how stem cells may be useful in repairing basement membrane matrix defects and rest...Stem cell study for patients with heart attack damage seeks to regenerate heart muscle
...ogists are hoping that transplanted stem cells can regenerate damaged heart muscle in those who experience a first heart attack. The study involves an intravenous infusion of adult mesenchymal stem cells from healthy donor bone marrow that might possibly reverse damage to heart tissue. A unique benefit of the s...Bile acids, receptor key in regenerating livers
...s (such as drugs used to lower cholesterol) cannot regenerate liver. Drugs could be developed to take advantage...is flesh and his liver. Overnight, the liver would regenerate and heal. With the dawn, the dreadful process began again. In a way, said Moore, these studies are ...Brittlestar provides new model for stem cell research
...ormis, is a close relative of the starfish and can regenerate lost arms in a matter of weeks. Sam Dupont and Mike Thorndyke are presenting their latest work on Friday 7th April at the Annual Meeting for the Society for Experimental Biology [session A8]. "What is really amazing is that the nervous system starts ...Liver cancer linked to cellular repair pathway
...e study. The liver's attempts to repair itself and regenerate new tissue after injury can trigger the Hedgehog pathway. During embryonic development, Hedgehog tells cells where and when to grow. In adult tissue, it signals the body to grow new tissue. "If the liver is injured badly, it uses some of the same mec...Rice bioengineers pioneer techniques for knee repair
...ur bodies including skin, blood vessels and bone regenerate themselves constantly. Tissue engineers try to capitalize on the body's own regenerative powers to grow replacement tissues that can be transplanted without risk of rejection. Donor cells from the patient are used as a starting place to eliminate rej...High resolution 'snapshots' detail dynamics of a cocaine antibody
...such as 7A1, on the other hand, has the ability to regenerate after each new dose of the drug, making it far more effective than others in metabolizing cocaine. The study, which will be published in the February issue (Volume 14 Issue 2) of the journal Structure, was led by Ian A. Wilson, D.Phil., of Scripps Re......aid. Earth's microbes help clean water and air and regenerate nutrients used by all life. Planktonic microbes, microscopic organisms that float freely in the oceans, help maintain environmental balance and drive the planet's biogeochemical cycles of carbon, nitrogen, oxygen and sulfur. "Plants and animals are t...Advancing the biomedical frontier: Experimental Biology 2006
...nerative medicine (the novel role of stem cells to regenerate or repair damaged organs and tissues), the "$6 billion (hu) man (from bionic arms to retinal prostheses); fetal origins of adult diseases; and the biological basis of aging, among other topics. AAA keynote speaker, Dr. Judah Folkman, will discuss a n...NJIT engineer poised to take stem cell research a step forward
... your nerve tissue and the neurons. So I'd like to regenerate that nerve tissue by coaxing stem cells to turn in...at stem cells, when mixed with scaffolds, can help regenerate bone growth; and another proving that stem cells taken from one person can be successfully implanted...Logging may hinder forest regeneration, increase fire risk
...gon in 2002 found that allowing trees to naturally regenerate works about as well or better than logging and replanting, and that undisturbed areas may be at lower fire risk in the future. The research will be published Friday in Sciencexpress and later presented in the journal Science, by scientists from Orego...JCI table of contents: January 4, 2006
...ir follicles are the ultimate source of cells that regenerate the skin and the growth of new hairs. Vogel and co... specific follicular cell types for the ability to regenerate hair and skin, with the hope of developing novel methods for treating skin and hair disease." TITLE...MIT researcher finds neuron growth in adult brain
... While scientists have focused mostly on trying to regenerate the long axons damaged in spinal cord injuries, the new finding suggests targeting a different part of the cell: the dendrite. A dendrite, from the Greek word for tree, is a branched projection of a nerve cell that conducts electrical stimulation to ...Researchers uncover remarkable developmental pathway
...s to apply embryonic stem cells therapeutically to regenerate damaged or diseased tissue may have to overcome similar self-regulatory mechanisms present in stem cells. Such mechanisms might otherwise drive stem cells to attempt to differentiate into embryos with many cell types, rather than restricting themselv...USC researchers track down the stem cells that create feathers
...tem cells and adult human organs to regenerate-and regenerate properly."...New study identifies key gene in development of connections between brain and spinal cord
...duction could be essential in understanding how to regenerate connections to the spinal cord that are severed during injury, which results in paralysis. "The discovery of Fezl is a critical finding in unlocking the intricacies of human brain development," noted McConnell. "However, there is still much resear...Flatworm genes may provide insights into human diseases, researchers say
...e structures. Both planarian strains, however, can regenerate themselves when split. By comparing the machinery of the two strains, basic knowledge about stem and germ cell activity might be enhanced, Newmark said. "Many of the genes in this collection are going to be important for studying stem cell biology an...UCSF study finds nerve regeneration is possible in spinal cord injuries
...njury occurs in CNS cells, the cells are unable to regenerate on their own. In PNS cells, however, an injury can stimulate the cells to regrow. PNS nerve regeneration makes it possible for severed limbs to be surgically reattached to the body and continue to grow and regain function. Regeneration occurs becau...