Silenced gene in worm shows role in regeneration
... postulated three theories why the worms could not regenerate or maintain cells after smedwi-2 was silenced: The stem cells were not responding to tissue damage or homeostasis signals. The stem cell division progeny failed to migrate to the appropriate tissues. The daughter cells didn't know how to differe...Regenerating worms help elucidate stem cell biology
...atworm best known for its extraordinary ability to regenerate lost tissue, researchers have identified a gene th... -- head regression, curling, and the inability to regenerate -- suggesting that the gene was needed for normal neoblast function. The researchers examined piw...Figuring out the ups and downsand sidewaysof neural development
...control the division of adult neural stem cells to regenerate neural tissues. Researchers know that during the earliest embryonic brain development, neural stem cells divide "symmetrically," producing identical immature progenitor cells that continue to proliferate. A bit later, however, when neural tissues nee...New understanding of regeneration gained by Forsyth scientists
...e worm's cells communicate to correctly repair and regenerate tissue. Forsyth scientists have found that gap-junction (microscopic tunnels directly linking neighboring cells) communication contributes to this signaling. This research, led by Dr. Michael Levin, underlies principles that can potentially offer in...From one cell, many possible cures
...ential to repair damaged heart muscle tissue . . . regenerate injured bone . . . create new cartilage or skin . . . even reverse nerve damage. Human stem cells offer tremendous hope for the development of revolutionary medical treatments for these and a variety of other human health problems. Up until now, howe...Creeping crinoids! Sea lilies crawl to escape predators, new video shows
...hers found that some sea lilies regularly shed and regenerate the ends of their stalks. Interestingly, the stalks don't break off just anywhere, but at particular nodes, just below clusters of flexible, finger-like appendages. Baumiller and Messing speculated that the sea lilies might be shedding the ends of th...Neural stem cells are long-lived
...ode well for the use of these neural stem cells to regenerate brain tissue lost to injury or disease. Alexandra ... neural stem cells for therapeutic purposes and to regenerate tissue, it's important that they can continue to proliferate, and that these stem cells can make dif...Hair-raising stem cells identified
... of the stem cells in hair follicles to repeatedly regenerate all the different cell types of the follicle and s...tive medicine. The method could one day be used to regenerate hair on patients with severe burns. This study is a logical complement to other work in Barrandon's ...NHLBI funds new centers for cell-based therapy
...dy the development of stem cell-based therapies to regenerate the heart and to reverse heart failure in patients with ischemic heart disease. The team will initially study the use of bone-marrow derived mesenchymal stem cells as a treatment for ischemia (reduced blood flow to the heart). Mesenchymal stem cell...New research could help us deliver genes for new bone formation
UK scientists are working on new methods to regenerate cartilage and bone by delivering genes to stem cells within the body to instruct them to turn into bone cells. The research, funded by the Biotechnology and Biological Sciences Research Council (BBSRC), could lead to a new approach to tissue engineer...Study in Royal Society journal on possiblity of human organ regeneration
...reviously that only the early mammalian foetus can regenerate an organ spontaneously following severe injury to ... managed to retain their early foetal potential to regenerate organs; and that this dormant potential can be reactivated provided that medical researchers can ide...Adult human neural stem cell therapy successful in treating spinal cord injury
...used adult human neural stem cells to successfully regenerate damaged spinal cord tissue and improve mobility in mice. The findings point to the promise of using this type of cells for possible therapies to help humans who have spinal cord injuries. Study results appear online in the Proceedings of the National...Blood test for colon cancer risk to be goal of Hopkins project
... number of primitive cells that allow the colon to regenerate its lining. In addition to the practical science, the team will also evaluate the effectiveness of the informed consent process. "All research investigators are required to obtain informed consent from human subjects. But there is a lot evidence that...Embryonic stem cells accrue genetic changes
... pancreas cells in people with type I diabetes, or regenerate brain cells lost in a person with Parkinson's disease, for example. The analyses of the embryonic stem cell lines and the computer comparisons of the mounds of resulting data required the efforts of scientists at four academic centers, two federal l...Adult stem cells from adipose tissue could save lives
...dipose-derived stem cells can be used to repair or regenerate new blood vessels, cardiac muscle, nerves, bones and other tissue, potentially helping heart attack victims, patients with brain and spinal cord injuries and people with osteoporosis. The work to be presented reflects a growing number of researchers ...Human muscle-derived stem cells effective in animal models of incontinence
...he lab to identify exactly how these cells work to regenerate muscle. Clinical trials using muscle-derived cell therapy for incontinence have recently begun in Toronto. Urinary incontinence affects 13 million Americans. Those with stress urinary incontinence involuntarily lose urine while doing activities that...International stem cell meeting in Kobe, Japan
...e back the means by which some animals are able to regenerate cell, tissues, limbs and organs they have lost to aging, injury or disease. The knowledge gained from such fundamental studies already shows great promise in clinical applications as well, and the CDB will continue to work toward fulfilling its dual ...JCI table of contents September 1, 2005
....php?id=24617 PHYSIOLOGY TWEAKing the liver to regenerate after injury Liver injury can occur as a result of alcohol toxicity, necrosis, or a host of other factors. When the liver is injured, it responds with progenitor cell (oval cell) proliferation in the remaining parts of the organ. The oval cells ca...Scientists link genetic pathway to development of hearing
... hair cells, mammals lack the ability to naturally regenerate hair cells. Thus individuals born with improperly developed hair cells, or those who lose them through trauma, disease, environmental factors or aging, cannot regain their hearing. Reports from the National Institutes of Health (NIH) indicate that ...Story tips from the Department of Energy's Oak Ridge National Laboratory, August 2005
...tage. Optionally, PureComfort can provide heating, regenerate a desiccant (for humidity control) and provide coolant to a supermarket refrigeration system. This combination of multiple simultaneous electric and thermal outputs enables the system to achieve an overall fuel efficiency of more than 80 percent comp...