UGA scientists unravel 'molecular inch-worm' structure of walking-pneumonia bacterium
... with very small genomes, lacking the typical cell regulatory mechanisms found in other bacteria. And yet some species such as M. pneumoniae posses this complex terminal organelle. We've been able to observe it in growing cultures and describe the choreography of events at a level of detail not previously possi...AIUM supports FDA decision to deny over-the-counter use of handheld doppler fetoscopes
... the scientific community substantiate the current regulatory status of these devices, which provides access for home use when the mother and her physician decide such monitoring is indicated."...Insights into activity-dependent neuronal growth through RSRF-supported research
...ional process. Moreover, they identified a complex regulatory loop in which BDNF feeds back to trigger phosphorylation of MeCP2, suggesting that BDNF and neuronal activity may cooperate in regulating MeCP2 function. Finally, this study shows that MeCP2 phosphorylation at S421 occurs only in the brain and not in...Protein important in blood clotting may also play a role in fertility
...road." The discovery suggests that CIB1 is a major regulatory protein, active in cell function throughout the body, said Dr. Leslie Parise, senior author, professor of biochemistry and biophysics and pharmacology and chair of the department of biochemistry and biophysics. "This protein is known to regulate cell...Scientists identify switch for brain's natural anti-oxidant defense
...colleagues, using a mouse model, discovered that a regulatory protein, PGC-1a, switches on the anti-oxidant syst...8. It has subsequently been found to play a master regulatory role in metabolic processes and muscle function, as well as being a culprit in diabetes. The report...Successful one year gene therapy trial for Parkinson's disease announced by Neurologix
...ause it may take years to develop, test and obtain regulatory approval for a gene-based therapy product before i...sustain profitability. In order to obtain the regulatory approvals necessary to commercialize its current or future product candidates, from time to time the...Potassium limitation, ammonium toxicity and amino acid excretion in yeast
... without stimulating innate ammonium concentration regulatory mechanisms, the cells engineered to let in more ammonium showed greater mortality even in high potassium concentration, supporting the idea that ammonium is the root of the problem. Also in these engineered cells, growth was limited even though potas...InHealth awards two research grants to Stanford University
...g technology. The other will document the current regulatory and commercialization processes required of new me...g diagnostic imaging's role in medical care and on regulatory policies that affect diagnostic imaging facilities. Laurence Baker, Ph.D., chief of Health Services...New fertilizer SRM can help control heavy metal content
...ilizers. While fertilizer manufacturers and state regulatory authorities have needed to develop analytical methods to implement these regulations, until now there have been no certified reference materials available that they could use to validate the accuracy of their measurements. It can be difficult to meas...16 outstanding researchers receive Singapore's highest honor in science and technology
...lying developmental mechanisms because the genetic regulatory mechanisms of many cognate developmental processes are conserved in different eukaryotic systems. Dr Yu is currently working on the construction of blueprints for the initiation and maintenance of transcriptional networks involved in complex developm...Longer-lived rodents have lower levels of thyroid hormone
... maximum species lifespan and suggest an important regulatory role of thyroid hormone in longevity," the researchers concluded. However, because T3, levels did not differ significantly among all the groups, further research in this area using larger sample sizes (numbers of rodents in each group) is needed, Pin...Squeeze play: Protein's grip like a baseball bunter's
...the importance of maintaining a good grip. A vital regulatory protein in all plants and animals, calmodulin is known to grab hold of hundreds of different proteins inside our cells, and it typically uses a grip that would make a Little League coach proud: it holds its two clasping lobes firmly together, one ato...Three UCSF faculty elected to Institute of Medicine
...f Psychiatry at UCSF. His research focuses on the regulatory genes that orchestrate development of the forebrain. In the mammalian embryo, the forebrain is the portion of the neural tube where primitive cells are organized to form the cerebral cortex, the basal ganglia and other components of the adult brain -...Animals resistant to drunken behavior offer clues to alcoholism's roots
...at the ethanol-resistant flies failed to produce a regulatory protein underlying the sedative effects of alcohol. The lacking protein is one of three encoded by a single gene and is also suspected to influence the cytoskeleton of neurons, though indirectly. "Most researchers in the alcohol field have focused...Columbia University Medical Center receives major new NIH Clinical Science 'investment' funds
...ostatistical and clinical trial design, bioethics, regulatory issues, and patient-oriented research. Supporting basic science graduate students interested in expanding into clinical research and funding for clinical researchers to do rotations in basic sciences. A new Ph.D. program in clinical research one of...Rockefeller University receives $45 million from NIH for clinical and translational science
...biostatisticians, research pharmacists, experts in regulatory issues, and others work with the clinical and basi... of human subjects, biostatistics, bioinformatics, regulatory issues, and methods of partnering with biotechnology and pharmaceutical companies. Rockefeller Unive...Researchers receive $12.8 million NIH grant to improve diagnosis/treatment of chronic lung disease
...tigator Anuradha Ray, PhD, of Pitt, has shown that regulatory T cells, also known as the "the gatekeepers," can suppress allergic responses and control allergies in humans. The ability of these cells to control allergic responses may be critical in determining which patients develop allergy and which patients d...New angiogenesis finding may help fight cancer growth
...itors are under study at this point, but finding a regulatory molecule that affects four separate mechanisms "makes for an interesting package," Bresnick says. The Wisconsin Alumni Research Foundation has applied for a patent on the discovery, which, says Bresnick, reflected the work of "outstanding collabor...How nature tinkers with the cellular clock
...t is really surprising is the speed at which these regulatory systems evolve. We are talking about roughly 100 m... the question in how far general conclusions about regulatory systems can be drawn from studying simple model organisms like yeast or fruit flies....USGS at The Wildlife Society: From sea-ice change to contaminants to predators and prey
...rmation on seabird distribution is needed to allow regulatory agencies to evaluate placement of proposed wind energy projects. To address these information needs, seabird occurrence, biophysical parameters, and oceanographic data are being gathered for the Atlantic waters of the eastern United States, a focal a...