MIT, Brigham: Nanoparticles armed to combat cancer
...mors in five of the seven treated animals, and the remaining animals also had significant tumor reduction, compared to the controls," said Dr. Omid C. Farokhzad, an assistant professor at Brigham and Women's Hospital and Harvard Medical School. Farokhzad and MIT Institute Professor Robert Langer led the team o...Evolution follows few of the possible paths to antibiotic resistance
...are no more fit than the original gene, and of the remaining 18 Weinreich and colleagues observed that only about half actually had a significant probability of evolutionary occurrence. "To be followed by an evolving population, natural selection requires that antibiotic resistance increase with each mutation,...'Dead zone' summer killed billions of ocean state mussels
...rchers found one reef completely wiped out. Of the remaining eight, seven were severely depleted. The ecologists estimate that the number of mussels that died was roughly 4.5 billion, or about 80 percent of the reefs' population. Just one month before hypoxia hit, researchers surveyed the same reefs and saw ac...Separate genetic mutations gave people, chimps bitter-taste sensitivity
...rcent of people worldwide can taste PTC, while the remaining quarter can't. PTC tasters are less likely to smoke cigarettes than non-tasters, but they're also less likely to eat cruciferous vegetables, such as broccoli, that are important sources of nutrition, Wooding said. Differences in PTC sensitivity were ...Bile acids, receptor key in regenerating livers
...ece of liver," said Moore "Instead, you expose the remaining portion to a higher relative amount of bile acids, sending a signal through a specific receptor called FXR to activate liver regeneration." Animals bred to lack FXR have difficulty regenerating liver, he said. And when he and his colleagues fed anim...Forget a better mousetrap: Save the forest
...d Fijian land snails which live deep within Fiji's remaining forests. By using bait stations designed to attra...t edge were rarely visited. "Protection of the few remaining large blocks of natural forests on Pacific islands may be the most cost-effective approach for conse...Mapping dynamic Polycomb group proteins during Drosophila development
...on of a fly will be to extend this analysis to the remaining Drosophila chromosomes, across other developmental stages, and in different tissue types. From there, scientists can similarly probe what makes a mammal, and the extent to which these mechanisms are conserved across distant species....How embryonic stem cells maintain their identity
...at of muscle or nervous tissue, for example--while remaining "poised for activation." Human embryonic stem cells can be kept in an undifferentiated state and selectively induced to form many specialized cell types, which could potentially replace cells lost or damaged by disease. The new findings may therefore...... PDR has some of the most significant forest areas remaining in Southeast Asia. However, the combined loss of forest cover (estimated at nearly 55 percent) and over-exploitation of many species threatens much of Laos's wildlife. Already, a newly described salamander species found by Stuart in Laos has turned ...Joslin-led study reveals findings on how insulin-producing beta cells grow and function
.... "When you knock out one receptor at a time, the remaining receptor can compensate for the other since both are so similar," says Dr. Kulkarni. "In this study, we knocked out both at the same time and still didn't see a defect in the developmental growth of beta cells. Our conclusion is that there are growth...International support for Swedish stem cell research
...man embryonic stem cells to readily multiply while remaining in an "undifferentiated" state, as increased knowledge about the basic properties of embryonic stem cells will help scientists as they manipulate these cells for further research into developing therapies for diseases like diabetes....Bioportfolio: Life-long persistence of erythrovirus DNA genomes in human tissue
... "Bioportfolio" to describe viral genomic material remaining in the human body after infection. Using human erythrovirus as the example, the authors have demonstrated that viral genomic material persisting in the human body yields valuable information on viral phylogeny and on molecular epidemiology of infecti...Coral reef resilience: Better feeders survive bleaching
...re severely damaged or dead and that 60 percent of remaining reefs will vanish by 2030. Several factors are to ...thetic rates, and lipid levels in some corals. The remaining corals were returned to the reef to recover. After two weeks on the reef, researchers covered some o...Computers to save unique type of American red squirrel
...000 red squirrels, Kielder hosts England's largest remaining population. In Kielder, Newcastle University's Dr Peter Lurz and colleagues used the model to create a conservation strategy for the forest, assisting with planting and felling plans to help maintain a viable red squirrel population. Here, the red...Inflammation markers identify fatigue in breast cancer survivors
... survivors compared to the amount of that receptor remaining on the membranes of specific blood cells where the receptor normally is found and functions within the immune response. The IL-6R is usually embedded on the surface membrane of white blood cells, or monocytes. In some survivors, however, many of th...Diverse sea 'bugs' revealed on landmark Atlantic cruise to census zooplankton
...lluminate these important little life forms in the remaining three quarters, below 1,000 m, the point at which the deep sea (bathypelagic zone) is generally agreed to begin. The expedition was funded by the National Oceanic and Atmospheric Administration (NOAA), as part of its Ocean Exploration program, and...Gladstone scientists prove neurons produce Alzheimer's-linked apolipoprotein E
...luorescent protein that represents apoE, while the remaining allele functions normally. Thus, under a microscope, the bright green fluorescence, dubbed EGFPapoE, shows researchers wherever the apoE gene is expressed. "This study lays to rest a long-standing controversy concerning the neuronal expression of ap...Ready, set, mutate and may the best microbe win
... of days, and the final two fought it out over the remaining three weeks of the test. The research included a raft of additional experiments as well. The team characterized each of the mutant proteins to document precisely how it aided in metabolic regulation. The fermentor experiment was repeated and the same...Scientists develop first comprehensive theory explaining Madagascar's rich biodiversity
...and prioritize conservation efforts in the limited remaining natural forests of Madagascar, the most biodiverse...ority to zones with high levels of micro-endemism, remaining forests, and little-to-no current protection," Goodman says....Giant deep-sea tubeworm's meal ticket comes in as a skin infection
...h during feeding, somehow escapeddigestion, and by remaining in the stomachcaused it to undergo metamorphosis into thetrophosome. But those conclusions were based on a verysmall set of observations, due to the extremedifficulty of obtaining the tubeworm's larvaland juvenile stages. The only way to collectthese...