Carnegie Mellon University research reveals how cells process large genes
...them down in a predictable fashion and joining the remaining exons. The findings are published this summer in Genetics. This process, which the investigators discovered in the fruit fly Drosophila, has been conserved over tens of millions of years of insect evolution and also appears likely to occur in humans,...Researchers devise new technique for creating human stem cells
...erted to an embryonic state." Melton said that the remaining technical hurdle is figuring out a way to eliminate the embryonic stem cell nucleus in the hybrid cell, causing it to have a normal number of chromosomes. One problem, said Melton, is that the nucleus in stem cells is large, occupying nearly the enti...New look at DNA hints at origin of ultraviolet damage
...hotolesions and filling in new material, using the remaining DNA strand as a template. If UV damage is confined to one side of the DNA double helix or the other, then the undamaged side makes an easy template for the proteins to follow. But if both sides of a strand were damaged, then the template would effect...International stem cell meeting in Kobe, Japan
...the meeting will help to clarify the potential and remaining challenges of this promising research area. The workshop is jointly organized by the Ernst Schering Research Foundation (Germany), the Max Planck Society (Germany) and the Riken Center for Developmental Biology (Japan) as part of the "Germany in Japa...Big differences in duplicated DNA distinguish chimp and human genomes
...e human genome over millions of years. Most of the remaining one-third of duplication differences are due to deletion of segments in one of the two species the segment is deleted from the genome, copy by copy, over time. The researchers found that many of the species-specific duplications have also caused di...Embryonic stem cells accrue genetic changes
...lready planning to conduct similar analyses of the remaining NIH-approved cell lines, but analysis of stem cell lines not available for use with federal funds will also be needed, the team members say....Study shows how respiratory disorder slows some racehorses
...e animals with EIPH of grade two or higher. Of the remaining 139 horses with the disorder, 101 were diagnosed with grade two; 25 had grade three; and 13 horses had grade four EIPH. The more severe the disorder, the further behind the winner a horse was likely to place. "We could actually quantify the distance ...Tips from the journals of the American Society for Microbiology
...st a variety of microbes. With sexual intercourse remaining as the most common mode of HIV infection throughout the world, a topical solution capable of inhibiting transmission of the virus at mucosal sites could significantly impact prevention efforts. In the study fourteen peptides from various amphibian sp...U-M researchers identify new blood test for prostate cancer
...the researchers validated their findings using the remaining 128 blood serum samples. They found eight of 68 controls and 11 of 60 prostate cancer samples were misclassified. This means 88 percent of the time, samples that were not cancerous were correctly identified and 81.6 percent of the time, samples that ...Hopkins scientists uncover 'tags' that force proteins to cell surface
...he protein ended up on the cell surface instead of remaining inside the cell. The researchers found three major classes of such tags, grouped according to similarities in their sequences of building blocks, and delved into the most potent of them. By using a computer program developed by graduate student Brian...Mechanism regulating tooth shape formulation found
One of the remaining challenges for evolutionary developmental studies of mammals, whose evolution is best known from their teeth, is how their tooth shape is altered during development. Researchers of the University of Helsinki together with their Japanese colleagues fr...Neurologix announces positive results of gene therapy clinical trial in Parkinson's disease
...luated one year following treatment. Three of the remaining five subjects have been followed for six months and the remaining two for more than four months. The trial results were presented by Andrew Feigin, M.D., Associate Di...How a zebra lost its stripes: Rapid evolution of the quagga
...sked how and when the quagga diverged from all the remaining related horses, zebras, and asses. They compared the genetics, coat color and habitats of existing zebras with related extinct species. The mitochondrial DNA markers from 13 museum specimens, including the only skeleton in museum collections, which i...Preserving a 460 year old wreck
...hat chemical treatments to remove or stabilize the remaining iron and sulphur compounds, and reducing humidity and oxygen access, are requirements for long-term preservation. At the Mary Rose Trust they are already investigating new treatments to prevent new acid formation. For slowing down the organo-sulphur...Columbia wins major grant to examine genetic link to Alzheimer's Disease
...ting GCC at Columbia University, and work with the remaining 12 centers on coordinating follow up with the families that are already participating in the study. "Many steps in the development of the disease remain unknown, and we may be able to understand the process more fully with the discovery of more gene...Microarray technology for tailoring breast cancer therapy
...elapse or death from any cause within 5 years. The remaining 121 patients were defined as the 'good prognosis' group. The researchers also used gene expression profiling to separate patients who did well with and without adjuvant therapy, and those whose tumours failed to respond to treatment. An analysis of t...Woods Hole Research Center scientist part of international initiatives to save the great apes
...nited Nations auspices in 2001 to save the world's remaining great ape population. GRASP aims to establish strategies for all regions of Africa and Asia where apes survive. Based on GRASP preliminary findings, Africa has more than 70 percent of the priority Great Ape populations. It is not surprising that 51 ......se reefs over the past three decades. However, the remaining healthy reefs still support dense and diverse populations of more than 70 fish species and are critical breeding grounds for commercially important populations of gag and scamp grouper as well as rock shrimp. The reefs' location directly under the Gu...University of Delaware researchers develop cancer 'nanobomb'
...ed inoperable. Nanobombs can be used to target any remaining cancerous cells and can be used in any part of the body, allowing the creation of nanobomb therapy for a wide variety of cancers. Panchapakesan said the method is far better than modern chemotherapy, which is non-selective, kills normal cells as we......rch choice. Typically, the embryos used are those remaining at the conclusion of fertility treatments that would otherwise be discarded or kept in frozen storage; a ban on the use of Federal funds to create new stem cells using these embryos currently is in effect, and various pieces of legislation pending in...