A possible mechanistic link between stress and the development of Alzheimer tangles
... However, when Rissman simulated chronic stress by repeating the procedure every day for two weeks, the modification lasted long enough to let tau molecules tumble off the cytoskeleton and pile up in insoluble heaps of protein. The first thing you consider when you think about stress-induced changes in the ...Exploring the dark matter of the genome
...t it's harder to know how shorter pieces with many repeating sequences, typical of heterochromatin, fit togethe...eins, and other functional elements. Moderately repeating fragments like transposons and single-copy genes were assembled by comparing numerous copies with un...St. Jude shows gene test not needed if cancer drug given in low doses
... building blocks called thymidine and adenine (TA) repeating several times just in front of the gene itself. This area, called the promoter region, acts as an on switch that triggers the reading of the gene. The normal UGT1A1 has six copies of TA in front of it, while UGT1A1*28 has seven. Previous studies h...Orangutans' communication resembles a game of 'charades'
...f signals by focusing on gestures already used and repeating them frequently. In contrast, when completely misunderstood, orangutans elaborated their range of gestures and avoided repetition of "failed" signals. The response showed that the orangutan had intended a particular result, anticipated getting it, ...Gene predicts better outcome as cortex normalizes in teens with ADHD
...s called the 7-repeat because it contains the same repeating sequence in its genetic code seven times. Everyone inherits two copies of the D4 receptor gene, one from each parent, so some people have two copies of the same version while others may carry two different versions. For the current study, the rese...