New proteomics research promises to revolutionize biomedical discovery
...m objective which is to build a publicly-available repertoire of molecular maps that represents the fingerprint ... of some disease conditions. If this comprehensive repertoire of protein interaction networks, termed the Human Proteotheque, can assist scientists worldwide in i...UCLA researchers show that culture influences brain cells
...in-group membership and a culturally learned motor repertoire more strongly influence the brains responses to observed actions, specifically actions used in social communication. An important conclusion from these results is that culture has a measurable influence on our brain and, as a result, our behavior....JCI table of contents: July 12, 2007
...cell clonotype within a heterogeneous autoreactive repertoire is dominant in driving EAE AUTHOR CONTACT: Eli E. Sercarz Torrey Pines Institute for Molecular Studies, San Diego, California, USA. Phone: (858) 455-3824; Fax: (858) 455-3715; E-mail: esercarz@tpims.org View the PDF of this article at: https...Doing nature one better: Expanding the genetic code in living mammalian cells
...e developed a novel strategy to expand the natural repertoire of 20 amino acids in mammalian cells, including neurons, and successfully inserted tailor-made amino acids into proteins in these cells. In a powerful demonstration of the methods versatility, they then used unnatural amino acids to determine the ope...Potent possibilities for parasite attack
... similarity to human genes, they present a limited repertoire of potential targets for drug and vaccine development allowing researchers to optimise the use of limited resources." Leishmaniasis is one of the neglected diseases that desperately need new research, as WHO/TDR notes: "Treatment of visceral leish...Eavesdropping comes naturally to young song sparrows
...g their own territory, they modify and prune their repertoire so their songs are more similar to their neighbors. A song sparrows repertoire crystallizes at around 10 to 11 months of age and does not change. Beecher and his colleagues earli...Antibody-based therapies effective at controlling malaria
...archers developed these novel reagents by antibody repertoire cloning generated from immune Gambian adults. While it remains unclear if in vitro assays are predictive of functional immunity in humans, due to the lack of suitable animal models, according to this study antimalarial efficacy of human antibodies...Female-led infanticide in wild chimpanzees
...ad appear to represent part of the female behavior repertoire in chimpanzees. What drives the behavior is not yet clear, but may stem from demographic shifts that alter sex ratios and put increased pressure on females competing for foraging areas. In their report, the authors note that the Sonso community had...Corals -- More complex than you?
... a simple creature should have such a huge genetic repertoire is a mystery, but scientists are excited by it bec...se that, by exploring the ancestral immune genetic repertoire of corals and how it functions in a simple animal, we will gain new insights which will help in the ...Gene that governs toxin production in deadly mold found
...he loss of LaeA results in a great decrease in the repertoire of secondary metabolites, which appears to impact the infection process," making the gene an ideal prospect for new ways to fight infection. ...Male owls pitch their hoots to advertise body weight to competitors
...he calls rather than in the diversity of the vocal repertoire as it is in songbirds," says Reby, who is an expert in the study of mammal vocal communication. ......ion to date that they use their diverse camouflage repertoire at night. In a paper published in the April 2007 issue of The American Naturalist, MBL (Marine Biological Laboratory) Senior Scientist Roger Hanlon and his colleagues report, for the first time, that giant Australian cuttlefish employ night camou...Embryonic patterning makes the feathers fly
...way. Manipulating the MAPK pathway produced a wide repertoire of feather patterning, from spots, to stripes, to homogenous patches, all reflecting varying degrees of inhibited feather bud segregation. Stripes, for example, increased with higher inhibitor dosage and earlier times of administration. But which ...MIT: Engineered yeast speeds ethanol production
...g gene transcription and, in turn, controlling the repertoire of genes expressed in a particular cell. These types of transcription factors bind to DNA and turn genes on or off, essentially controlling what traits a cell expresses. The traditional way to genetically alter a trait, or phenotype, of an organism...'The Strangest Song' -- The story of the link between a rare genetic disorder and musical talent
...ng, with a classically trained lyric soprano and a repertoire of hundreds of songs in Italian, French, German, Japanese, Chinese, Macedonian, Korean, Hungarian, Yiddish, and many other languages. Since she can't read music, each note, each word, each nuance, is stored in her brain, which is only 80 percent as l...A prickly subject: The sea urchin genome is sequenced
...anism's cells that there is an intruder. The rich repertoire of such proteins in sea urchins could end up providing new tools for use against infectious diseases. Sea urchins are also extremely good at dealing with potential chemical threats in their environment through a "defensome" a group of genes wh...Decoded sea urchin genome shows surprising relationship to man
...l, and signal that there is an intruder. This rich repertoire of sea urchin proteins could turn out to provide new reagents in the fight against infectious diseases. 3.) The sea urchin has genes for sensory proteins that are involved in vision and hearing in man. Yet the sea urchin has no eyes and ears, at lea...Sweet yet sophisticated: Honey bee genome lends insight into sociality, sensation and sex
...tson and Kevin Wanner have identified the complete repertoire of receptors responsible for capturing these cues. In their Genome Research article, Robertson and Wanner report the identification of 163 olfactory receptors, which is more than twice the number in fruit flies (62) and mosquitoes (79). "The expa...Genomic comparison of lactic acid bacteria published
...117103v1 ). The small LAB genomes encode a diverse repertoire of genes for efficient carbon and nitrogen acquisition from the nutritionally rich environments they inhabit and reflect a limited range of biosynthetic capabilities promising broad industrial applications. Lactic acid-producing bacteria play a key...GlycoFi and Dartmouth report full humanization of yeast glycosylation pathway in Science
...ngineered yeast cells capable of producing a broad repertoire of recombinant therapeutic proteins with fully hum...t glycosylation system to fully replicate the full repertoire of human glycosylation reactions has been a challenging six year effort that many doubted could be a...