Tag: "replacement" at biology news
PCRM develops world's first cruelty-free insulin assay
...n-vitro, or test-tube, procedure using a synthetic replacement
for the fetal calf serum used as a culturing mediu..., peptide- and protein-free, media supplement as a replacement
for calf serum--basically a synthetic formula with cofactors and trace elements that promote cell gr...
Scientists rid stem cell culture of key animal cells
... Unexpectedly, Xu found that the presence of serum replacement
promoted stem cell differentiation. Digging deeper, he found that serum replacement
mimics the activity of bone morphogenetic protein (BMP), a molecule known to kick-start embryonic de...
Gene therapy converts dead bone graft to new, living tissue
...s cancers or injuries whose treatment involves the replacement
of large sections of bone. Cancers such as osteosarcoma, one of the most common types of bone cancers, or tumors that occur adjacent to bones, often must be treated by removing the diseased section of bone and replacing it with the only alternative a...
Helping the body heal itself: Regenerative medicine to be discussed at UH
...ell type or tissue is providing the basis for cell replacement
and engineered tissues," Polak said. "These may u...his new field directed toward long-term repair and replacement
of failing human tissues and organs. One of the most highly cited researchers in the world, she is ...
UCSD medical/bioengineering reseachers show titanium debris satobtage artificial joints
...tear can generate micrometer-sized particles. "As replacement
joints are becoming increasingly common in aging populations, our results explain how such devices fail and suggest that improvements should be made in artificial joint design," said the study's senior author K.L. Paul Sung, Ph.D., UCSD professor of...
Silence the gene, save the cell: RNA interference as promising therapy for ALS
...tor neurons, the Swiss researchers designed a gene replacement
technology that allows the knock-down of all mutant SOD1 forms while permitting the expression of a normal type SOD1 protein that is resistant to RNA interference-based silencing. Both these effects are expressed long-term via delivery by a single le...
Tiny scaffolding allows stem cells to become working fat cells
...ile waiting for a donor organ, or even providing a replacement
organ." Along with Xihai Kang and Yubing Xie, both postdoctoral fellows in his laboratory, Kniss built a fabric-like carpet of polyethylene terephathalene (PET), or Dacron, fibers that served as scaffolding upon which new fat cells were grown. In con...
NC State scientist finds soft tissue in T. rex bones
...ntially transformed into "rocks" through a gradual replacement
of all organic material by minerals. New research by a North Carolina State University paleontologist, however, could literally turn that theory inside out. Dr. Mary Schweitzer, assistant professor of paleontology with a joint appointment at the N.C....
Deficiency of growth hormone and IGF-1 reduces cancer and kidney disease, but creates other problems
...throughout life," they said. "Growth hormone/IGF-1 replacement
in older animals reverses the age-related decline in cognitive function." The group also found that "cartilage degeneration that normally accompanies aging is accelerated by the absence of growth hormone." The researchers concluded that cancer risk a...
Muscle-targeted gene therapy reverses rare muscular dystrophy in mice
...r dystrophies presents a unique challenge, because replacement
of deficient, therapeutic proteins invokes an immu...pe disease. The Duke team earlier developed enzyme replacement
therapy, in which a normal version of the faulty enzyme in those with the disease is infused weekly....
Six week mini-med school to focus on the fascinating science of aging
...risks and benefits associated with use of hormonal replacement
therapies being advocated by some as a way to alter aging. In the final session (May 26), Judith A. Salerno, M.D., NIA Deputy Director, and a panel of senior scientists from the Institute will set their sights on the future. They will report on the f...
Immune cells in the liver take a ride
...movement. But the researchers found that the replacement
of the gene did not affect the movement of NTK cells, they hung on and patrolled for invaders just as well as cells with the gene. However, their survival rate was reduced, leading the scientists to surmise that the gene was somehow involved directly...
Thumbnail sampler of 10 diverse physiology papers from IUPS 2005
...does exercise. Researchers found that testosterone replacement
had no effect on spontaneous activity, whereas estrogen did. Identifying gender differences and fctors affecting our activity could lead to a better understanding of an aging population. Next they will attempt to determine if the estrogen improved sp...
New technology, new approach to help heart and lung patients awaiting transplants
...ter assistive device, and ultimately, a mechanical replacement
for failing lungs. An interventional lung assist (ILA), developed by the German company Novalung GmbH, shows promising results. "Several hundred patients in Europe have been treated successfully with ILA," Griffith says. A non-invasive device, the I...
Why is Scotland's population shrinking and ageing? - A new research initiative
...950s and 1960s. It now stands 35-40 per cent below replacement
level (i.e. the number of births required to prevent population size falling). Outward migration is not a factor in declining population. About 70,000 people migrate to Scotland each year and approximately the same number of people leave Scotland e...
UW-Madison gains two new stem cell programs
...lls to application through the development of cell replacement
therapies. "The ultimate promise of regenerative ...rvous system and blood will be treatable with cell replacement
therapies," said Svendsen, a noted stem cell expert whose work is aimed at developing neural cells t...
Fungus-farming termites descend from an African rain forest Eve
...er-gatherers, or, and probably more often, through replacement
of local hunter-gatherers by farmers. The agricultural lifestyle has allowed both humans and their domesticated organisms to exploit unfavourable areas more effectively and to reach far higher population densities than each of their non-agricultural ...
PNAS highlights for the week of May 16 - 20
... be transplanted into mice to treat diabetes. Cell replacement
therapies for diabetes have been hindered by the limited availability of insulin-producing tissues, such as pancreatic -cells, and the need for lifelong immunosuppression. Previous research has shown that PDX-1 plays a central role in the development...
One gene links newborn neurons with those that die in diseases such as Alzheimer's
...n to those that are related to the choreography of replacement
itself." "In addition, because we study birds that learn their songs, the story relates to a fascinating, learned behavior, so it offers the opportunity to show how integration at different levels of biology can be made to pay," Nottebohm says. "It a...
Results of world's first gene therapy trial for arthritis show approach safe, feasible
...s were removed after one week during routine joint replacement
surgery. Nonetheless, with safety a key concern, t...ween 10 and 26 years. Each was scheduled for joint replacement
surgery involving the four knuckles on one of their hands and one additional joint. In the weeks pri...
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