White blood cells of cancer-resistant mice overwhelm natural defenses of cancer cells
... The discoverers of the unique mouse line that is resistant to cancer have begun to pin down how the process works and found that white blood cells in these mice overwhelm normal defenses of cancer cells. In a report in Cancer Immunity, a journal of the Academy of Cancer Immunology, posted on line today, Zhen...ACS News Service Weekly PressPac -- Oct. 25, 2006
...turates have a chemical trait that makes compounds resistant to biodegradation; so they expected to find traces of barbiturates in groundwater sites that had been infiltrated by wastewater decades ago. Knepper's group was surprised, however, to find significant concentrations of the drugs in a river. The rive...MIT engineers probe spiders' polymer art
... be flexible or stiff, water-soluble or insoluble, resistant to heat and chemicals and very strong. Silk protein solution consists of 30-40 percent polymers; the rest is water. The spider's silk-producing glands are capable of synthesizing large fibrous proteins and processing those proteins into an insolubl...MRSA vaccine shows promise in mouse study
...rries lung-damaging toxins. All five strains were resistant to most of the drugs used to treat S. aureus infections. "This microbe's ability to acquire the tools it needs to protect itself from the drugs we use to treat it is legendary," said study director Olaf Schneewind, M.D., Ph.D., professor and chairma...Three new lung tumor subtypes identified in DNA profiling study
...ncer is to spread and whether the tumor will prove resistant to chemotherapy. A report of the study, led by researchers at the University of North Carolina at Chapel Hill's Lineberger Comprehensive Cancer Center, appears in the November issue of the Journal of Clinical Oncology. Currently, lung cancer trea...U-M study offers new perspective on nitric oxide signaling in rheumatoid arthritis
...ndividuals with the shared epitope were completely resistant to cell death when compared to samples from individuals without the shared epitope. "It was previously postulated that nitric oxide plays a role in RA, since patients have higher levels of it in their joint tissue. When we looked at the rate of NO...Bee genome information housed at Texas A&M University
...make it simpler to select and propagate honey bees resistant to parasites and disease, and enable more accurate identification of Africanized honey bees." The object of mapping the genome is to show where genes are located on the chromosome, Elsik said. That work is well along. What is left, she said, is the...Looking to a new era in bee research
...faced by honey bees, including analyses of disease resistant pathways and metabolic adaptations to an all floral diet. Several papers address ways that honey bee studies can provide insights into human health. These papers cover the genetic bases of honey bee venom allergens, along with mechanistic insights i...Origins, spread of honeybees determined
...hile genes derived from other subspecies were more resistant to this replacement. This finding, according to Tsutsui, is important because the spread of Africanized bees northward from South America in recent years has had some negative consequences; not only are these bees more dangerous to humans because ...ACS News Service Weekly PressPac -- Oct. 18, 2006
...umans. ARGs are pieces of DNA that make bacteria resistant to common antibiotics - recognized as an increasingly serious global health problem. The genes can spread in different ways. Bacteria, for instance, exchange ARGs among themselves. Pruden and colleagues note that even if cells carrying ARGs have bee...Hormone resistance of pituitary tumors and Cushing disease explained
...nts of hormone because the tumor cells have become resistant to negative feedback control by a class of steroid...t will also help understand other forms of hormone resistant cancers. Dr. Jacques Drouin is the Director of the Molecular Genetics Research Unit at IRCM. He hol...Other highlights in the October 18 JNCI
... oxidative phosphorylation. Therefore, they can be resistant to programmed cell death under stressful conditions. The authors' findings could have therapeutic implications in that tumor cells might be treated to make them more susceptible to programmed cell death. Contact: Chifumi Kitanaka, ckitanak@med.id....ACS News Service Weekly PressPac -- October 11, 2006
...d the malaria parasite's deadly tendency to become resistant to anti-malaria drugs and in developing new drugs and vaccines for the disease. Malaria kills about one million people worldwide each year. About 90 percent are in Africa and 70 percent are children under the age of five. Georgetown University re...Malaria: Efficacy of monotherapies in Cameroon
...c have been seeing the emergence of parasite forms resistant to the most widely used treatments, especially to ...as subsequently conducted. The frequency of mutant resistant strains and the number of mutations were plotted for the different areas. The data obtained, such as...A new approach to the treatment of malaria in pregnant women in West Africa
...HTM. Malaria parasites are becoming increasingly resistant to choloroquine and sulphadoxine-pyrimethamine (SP) across Africa and there is a need to find new drugs which are safe and well tolerated. Most countries in Africa are adopting artesunate-based combination therapy (ACT) as the preferred first line t...Poultry consumption, handling are risk factors for antibiotic resistance in humans
...o human health." "We've known for a long time that resistant bacteria can be found on retail poultry products, ...ltry and from patients who consumed poultry became resistant to Synercid more often than E. faecium from vegetarians or from antibiotic-free poultry. Some of the...Study reveals mechanism for cancer-drug resistance
...iscovered a mechanism by which cancer cells become resistant to a specific class of drugs. They found that a ... have a chance to undergo mutations that make them resistant to anticancer drugs," said Dr. Michael Roth, professor of biochemistry and senior author of a paper ...Archerfish tune their shots to universal properties of prey adhesion
...to prey size, and that this strategy appears to be resistant to alteration by experience: It occurs even when the fish have been placed for two years in an environment that has been manipulated to make such tuning unnecessary for successful hunting. The findings suggest that the tuning aspect of the archerfish...Fruit fly study identifies gene mutation that regulates sensitivity to alcohol
... researchers found some fruit flies were much more resistant to alcohol sedation. These flies continued to move about much longer than typical fruit flies exposed to the same amount of alcohol. The scientists subsequently identified key differences in a particular gene associated with this behavior. The mutati...Discovery of the first resistance gene to rice yellow mottle virus
...ng the impact of RYMV is to be found in the use of resistant varieties. In certain rare traditional varieties ...med by genetic transformation. For this, a line of resistant rice was modified by transgenically introducing the allele for susceptibility of this gene. The desc...