Researchers in Montral and the US create model of key immune-system component
...ath in the world, and the phenomenon of antibiotic resistant bacteria worsens the situation each year. Thanks to the model developed by teams led by Michel Desjardins of the Department of Pathology and Cellular Biology at Universit de Montral, Drs Lynda Stuart and Alan Ezekowitz at the Massachusetts General Ho...Elusive rust resistance genes located
...ders around the world to breed more effective rust resistant wheat varieties. The genes, Lr34 and Yr18 are ...of resistance to speed up the delivery of new rust resistant wheat varieties." The marker has proven effective in a range of wheats from different backgrounds ...STAR*D study examines effect of genetic variation in treatment resistant depression
...ing to results from a major NIH study on treatment resistant depression released today at the annual meeting of...uffer from major depression, and who are treatment resistant with the same drug for a significant period of time. McMahon examined the effects of polymorphism...Protein's tail may be flu virus's achilles heel
...ally needed at the moment as some H5N1 viruses are resistant to the flu drug Tamiflu." Tao's findings are based on a painstaking series for experiments that revealed the atomic structure of NP. The protein's structure was discerned via X-ray crystallography, a method that allows scientists to discern the thr...Pendulums, predators and prey: The ecology of coupled oscillations
...nd why some predator-prey systems are particularly resistant to invaders. "In the past, ecologists have taken a traditional Newtonian view of the world, where everything comes into a nice equilibrium," Vandermeer said. "But oscillations sometimes destroy that equilibrium. What I'm suggesting is that we ecolog...New approach to BSE successful in lab
...which cannot produce any PrP-C. They would then be resistant to BSE....JCI table of contents: December 1, 2006
...y that is available to the body. When cells become resistant to the effects of insulin, type 2 diabetes and other metabolic disorders can develop. Understanding the molecular pathways by which insulin affects the different cells might provide clues as to why insulin resistance develops. Now, in a study appeari...New studies on Alzheimer's, autism, nicotine addiction and depression highlight annual meeting
... disease, autism, nicotine addiction and treatment resistant depression. SELECTED PANELS INCLUDE: Antihypertensive Drugs May Reduce Incidence of Alzheimer's Disease: Screening of a new cardiovascular drug suggests the potential to prevent cognitive decline associated with Alzheimer's disease. Geriatric p......panied by a frightening increase in the numbers of resistant Typhi. Investigations of a large strain collection... to Africa. In Vietnam, up to 95% of Typhi are now resistant to nalidixic acid and many other antibiotics. Although these cases can still be treated with newer a...Cloning techniques produce FDA-approved antibiotic
...alth, and demands new treatments effective against resistant pathogens. Fosfomycin is a natural antibiotic appr...e for the treatment of infections that have become resistant to the antibiotics penicillin and vancomycin. Fosfomycin is a member of a class of compounds called ...Safer method for large-scale malaria screening developed
...in studies to determine if a population is growing resistant to malaria drugs, which is a very serious problem," said David J. Sullivan, MD, senior author of the study and a professor in the Bloomberg School's Malaria Research Institute. The test uses polymerase chain reaction (PCR), a technique for duplicat...Does natural selection drive the evolution of cancer?
...tion of tumor cells, you're quite likely to have a resistant mutant somewhere in that population of billions or...en able to cure cancer is that we're selecting for resistant tumor cells. When we spray a field with pesticide, we select for resistant pests. It's the same idea...Nanotech tools yield DNA transcription breakthrough
...ding tuberculosis, strains such as XDR-TB that are resistant to current antibiotics have emerged." In additi... Soviet Union, were intentionally engineered to be resistant to current antibiotics. Ebright explained that his laboratory at Rutgers' Waksman Institute of Mic...Lab-on-a-chip could speed up treatment of drug-resistant pneumonia
... in the hospital, you're much more likely to get a resistant strain," Lochhead said. "It's an emerging public-health disaster." The most acute cases are admitted into intensive care units, where doctors have just days, if not hours, to save the patients' lives, Lochhead said. But reliably identifying the bac...Ludwig Fund donates $20 million to University of Chicago for cancer research
... and radiation by understanding how cancer becomes resistant to these treatments and shutting down those resist...l also be used to help identify patients that have resistant or sensitive disease and adjust treatments to match the molecular profile of each person's disease. ...Tailored treatments: Promising designer drug provides new insight into cancer biology
...ipulation of specific signaling molecules can make resistant cancer cells sensitive to treatment with ABT-737. ...arch in Australia and colleagues demonstrated that resistant cells can be sensitized to ABT-737 by using varied approaches that destabilize or inactivate MCL-1. ...UVa finds 'Alzheimer's gene' protects children from severe diarrhea
...e "dose" of the same gene, however, makes a person resistant to malaria, a deadly tropical disease. Oria adds that if the APOE4 gene indeed proves to be a balanced polymorphism, this could greatly help us understand and reduce the long-term impact of diarrhea and malnutrition. He says the genetic imprint ear...Researchers identify cells that make relapse inevitable in acute lymphoblastic leukemia
...sign therapies that will specifically target these resistant subclones so that, in the future, patients who hav...portant to know that these cells are actually more resistant and aggressive from the very beginning, like a evil twin, if you like. While the 'good' twin, or th...Europe's leading life science researchers are to convene for the first annual EuroBioForum
...able. When dry, desiccation tolerant organisms are resistant to extremes of temperature, radiation and pressure, and ageing is reduced or eliminated. There is, therefore, considerable scope for the industrial application of the desiccation process. And in an effort to better understand the effects of the thou......enic Staphylococcus aureus, including a multi-drug resistant variety. "The other clay actually helps the bacteria to grow," Haydel adds. What makes one clay kill bacteria, and the other promote growth? And why do most clays tested have no effect? Research like that being done by Williams and Haydel can answe...