$9M grant awarded to University of Cincinnati for bipolar disorder research
... disorder looks like in the brain, particularly in response to different treatments. Bipolar disorder is a ...ness. They will then view the brains physiological response to two mechanistically different, but widely used FDA-approved medications prescribed to treat bipol...A friendly foe -- Bacteria residing in the gut boost immune response to tumors
... from the gut to the lymph nodes, where the immune response to their presence increased the activation of tumor-specific CD8+ T cells and resulted in tumor regression. This effect was found to involve toll-like receptor 4. Conversely, a reduction in the number of host microorganisms by the use of antibiotics ...JCI table of contents -- July 26, 2007
...dly foe: Bacteria residing in the gut boost immune response to tumors One potent, immune-based treatment f... from the gut to the lymph nodes, where the immune response to their presence increased the activation of tumor-specific CD8+ T cells and resulted in tumor regr...Gene-transcription machinery seen poised for action, held in check until needed
...be prepared for nearly instantaneous activation in response to stress or other vital needs. Embryonic stem cel...y many vital cell functions that depend on a quick response which could be regulated by this process. In earlier work, Berger and her coworkers looked at ways...Females more prone to brain damage from alcohol abuse
...he VA, will examine the role that hormones play in response to alcohol withdrawal, include the possibility that the male hormone androgen exacerbates cell death in males. "What we're looking at now is the involvement of testosterone in mediating the cell death in females," Wiren said. "Not just in chronic c......ation of Central California waters is not simply a response to a localizedwarming of the ocean. Zeidberg and Robison suggest that Humboldt squid populations may be growing and expanding northward due to a decrease in the number of predators and competitors in their home range (the Equatorial Pacific). Chie...Prenatal alcohol exposure alters brain activity in the frontal-striatal areas
...gnetic resonance imaging (fMRI) while performing a response inhibition (go/no-go) task, designed to test their... nature of the blood oxygen level dependent (BOLD) response patterns, measured via fMRI, is still under study. One possible explanation is that the increase in...News tips from the Journal of Neuroscience
...jury of peripheral axons results in a regenerative response from the central as well as the peripheral process of a dorsal root ganglion (DRG) neuron. This conditioning effect is mediated by altered transcription of multiple genes and involves both enhanced axonal growth and reduced inhibition by myelin. Seij...Effects of aging in stem cells
...that genes involved in the inflammatory and stress response became more active with age, while genes important...he finding that genes involved in the inflammatory response are expressed more (called up-regulation) as HSCs age fits with evidence linking inflammation and ag......estion of this toxic milk sets off an inflammatory response in the skin of nursing pups, which ultimately disrupts the hair growth cycle and renders them largely bald. In fact, treatment with the common anti-inflammatory aspirin completely rescues hair loss in these pups.......ile there have been no scientific studies on birds response to human music, anecdotal evidence suggests that certain species of bird listen to and replicate human song. My interest with the piece was to get us to think about the impact we have on the other species around us, she adds. The bird listening...Identified main genetic variants involved in response to HIV
...region responsible for the determination of immune response capacity against a number of infectious diseases, ...n presents the highest correlation with the immune response described until now. Obtained information will be very useful in the long road to a more rational ...Genomic analysis uncovers new targets for HIV vaccine
...cine could be designed to elicit an HLA-C mediated response which HIV-1 might be unable to defuse. This study was the first time a genome-wide approach has been used for an infectious disease, Goldstein said. Past studies have looked at individual candidate genes. Since different people respond differently ...JCI table of contents: July 19, 2007
...sulin are not adequate to produce a normal insulin response from fat, muscle, and liver cells. The result is a...c (ie. they were not able to mount a normal immune response against this self antigen) and as such were able to prevent experimentally-induced hepatitis in thes...UC Santa Barbara scientists clarify molecular basis of interferon action
...found that with low PKR there is less apoptosis in response to some stimuli, said Zhang. (Apoptosis is cell death or suicide. It is a strategy, at the cellular level, to prevent growth of the virus.) The scientists found that protein synthesis, including the synthesis of an invading virus, is also a...Antibody-altering protein found in developing B cells
...make AID which directs and strengthens the B cells response to the infection by mutating the antibodies produced by the B cells. AID was originally thought to be made only by mature B cells and, as previously discovered by Imanishi-Kari and colleagues, in the developing B cells of transgenic mice. In the c...Exercise, exercise, rest, repeat -- how a break can help your workout
...d trial showed a significantly greater epinephrine response while also having a rapid decrease in insulin concentration as a result of lower plasma glucose. This combination of high epinephrine and low insulin concentration may have also increased the lipolysis. There was also enhanced fat oxidation in the ...Purdue-IU researchers explore new method for early disease diagnosis
...metabolites or ratio of metabolites can indicate a response to biological stress or a specific disease state. "The metabolic profile in biofluids, such as blood and urine, provides a snapshot of ongoing biological processes in the human body," Raftery said. "This type of analysis could be a key to earlier d...Gene identified for Crohn's disease in children
...thin the cell, they may stimulate the inflammatory response that characterizes Crohns disease. Although much research remains to be done, he added, better understanding of the disease process may guide doctors to new and improved therapies. If an excess of bacteria is the problem, we may find antibiotics ...... such pathogens and, if detected, mounts an immune response to stave off disease. As part of this surveillance system, tomatoes carry a protein in their cells called Fen that helps detect P. syringae and trigger an immune response. But some strains of P. syringae have evolved the AvrPtoB protein that mimi...