OHSU scientists find antidepressant, bone loss link
...est older men and women taking selective serotonin reuptake inhibitors, a class of antidepressants that includes Prozac, Paxil and Zoloft, are prone to increased bone loss. The jointly released studies by scientists at Oregon Health & Science University, and in San Francisco, Minneapolis, San Diego and Pitt...IMS updated recommendations on postmenopausal hormone therapy
...urther studies are required. Selective serotonin reuptake inhibitors, selective noradrenaline reuptake inhibitors and gabapentin are effective in reducing vasomotor symptoms in short-term studies. Their ...Orexigen reports positive phase II results for Excalia Combination-Therapy to treat obesity
...nation of bupropion, a dopamine and norepinephrine reuptake inhibitor, plus zonisamide, an approved anticonvulsant medication. OREXIGEN's preclinical research suggests that combining these two central nervous system drugs acts on a complex of neurons in the hypothalamus, the area of the brain contributing to ...Forsyth scientists find linkages between serotonin reuptake inhibitors and bone mass
...ve cells (osteoclasts). (Fluoxetine is a serotonin reuptake inhibitor (SSRIs).) However, it was not clear what role serotonin played in bone metabolism. Summary of Study Trabecular bone, one of two main types of bone, is spongy, and makes up the bulk of the interior of most bones, including the vertebra...Effectiveness of certain antidepressants may be influenced by gene variations of individuals
...nce antidepressant response to selective serotonin reuptake inhibitors (SSRIs a class of antidepressant drugs...ssociations between the efficacy of norepinephrine reuptake inhibitors (NRIs - a class of antidepressant drugs) and norepinephrine transporter (NET) polymorphis...Prozac exposure found to disrupt mussel reproduction
...ed the effect of fluoxetine, a selective serotonin reuptake inhibitor (SSRI) on a native freshwater mussel (Elliptio complanata). Fluoxetine, sold under the trade name Prozac TM , is one of the most heavily prescribed antidepressants in the United States. In humans, it acts to increase the levels of serotonin...Common anti-depressants similarly safe and effective for treating postpartum depression
...o compare the effectiveness of selective serotonin reuptake inhibitors (SSRIs) and tricyclics, two commonly used classes of antidepressants, in women who experience major depression after childbirth. "We've been treating postpartum depression based on the assumption that drugs that work for a woman with d...Study contradicts USA warning that an antidepressant can cause congenital abnormalities
...ing about the drug, which is a selective serotonin reuptake inhibitor (SSRI), was issued on the basis of unpublished research. "It showed that the absolute rate of major congenital malformations seen in the first trimester for paroxetine users was 4%, and 2% for cardiovascular malformations. Yet the retrospec...Researchers identify OCD risk gene
...(SERT), site of action for the selective serotonin reuptake inhibitors (SSRIs) that are today's mainstay medications for OCD, other anxiety disorders, and depression. "Improved knowledge of SERT's role in OCD raises the possibility of improved screening, treatment, and medications development for that disorde...Gene influences antidepressant response
...nced some improvement with the serotonin selective reuptake inhibitor (SSRI) citalopram (Celexa). The NIH scientists set out to find genetic factors that might help to explain why some patients fared better than others. They screened genetic material from 1,953 of the STAR*D patients, a sample with a higher ...Nobelist discovers antidepressant protein in mouse brain
...he surface of receiving cells. Serotonin selective reuptake inhibitors (SSRIs), medications commonly prescribed for anxiety and depression, compensate for reduction in serotonin signaling by boosting levels and binding of serotonin to receptors. Previous studies have suggested that serotonin receptors are ess...Gene variation affects tamoxifen's benefit for breast cancer
...Effexor does not. These drugs, selective serotonin reuptake inhibitors or SSRI's, are often used to treat hot flashes, a common side effect of tamoxifen. In this current study of 256 women with breast cancer, researchers also found that women with the CYP2D6 variant were less likely to have hot flashes. Any h...Transporters for the brain chemical serotonin provide
...rotonin-related drugs like the selective serotonin reuptake inhibitors (SSRI antidepressants such as Prozac and Zoloft) or the monoamine oxidase inhibitors (MAOIs)." This study, published in the most recent issue of Developmental Neuroscience, has ramifications for neuroscience, developmental genetics, evolu...Sept/Oct 2005 Annals of Family Medicine tip sheet
...clic antidepressants (TCA) and selective serotonin reuptake inhibitors (SSRI) are significantly more effective than placebo in primary care settings. Additionally, the study finds that the relatively low doses of TCAs sometimes used in primary care may be effective. Efficacy and Tolerability of Tricyclic ...Multiple genetic 'flavors' may explain autism
...s of serotonin in their blood. Selective serotonin reuptake inhibitors (SSRIs), drugs used to treat depression, anxiety and obsessive-compulsive disorders, also improve some of the symptoms of the disorder. These findings have led scientists to propose that serotonin plays an important role in autism. In the...Scientists discover the body's marijuana-like compounds are crucial for stress-induced pain relief
... to something like Prozac, which blocks the body's reuptake of the compound serotonin, causing it to be active longer, Hohmann said. Apparently, several parts of the brain are involved in the effect, most notably a structure in the midbrain known as the periaqueductal gray. In this region, stress causes the r...Managing maternal depression during pregnancy presents significant challenge to clinicians
...s for antidepressants known as selective serotonin reuptake inhibitors. Now the label for these drugs includes information about potential adverse effects to newborns if the drug is taken late in pregnancy," said Dr. Moses-Kolko, who also is on staff with the Women's Behavioral HealthCARE program of the Weste...Brain chemical serotonin involved in early embryo patterning, Forsyth scientists find
...rotonin-related drugs like the selective serotonin reuptake inhibitors (SSRI antidepressants such as Prozac and Zoloft) or the monoamine oxidase inhibitors (MAOIs). Could lead to a greater understanding of potential health risks from drug families that target the serotonin pathway in human patients. Shed...Virginia Tech patents advance microprocessors, vaccines, vision, vibration control, more
...e and released from presynaptic neurons, or if the reuptake of neurotransmitters by these presynaptic neurons ...ve the unusual property of potently inhibiting the reuptake of serotonin, norepinephrine, and dopamine. Current FDA-approved antidepressant drugs do not exhibit......r said a class of drugs called selective serotonin reuptake inhibitors (which include Zoloft, Paxil and Prozac) have proved safe in patients with epilepsy....