Scientists reveal structure of gateways to gene control
...teway to transcription," Pugh said. The research reveals how the pieces of DNA that regulate genes at the transcription-promoter sites are packaged on nucleosomes. The knowledge that these sites are located on the outside edge of the nucleosome spool will help to focus research designed to manipulate gene...Blood's clotting cells harbor 'ticking time bombs,' finding may help extend blood supply
...ival genes in tumor cells. Bcl-xLs newfound role reveals that the new cancer drugs will likely lead to a decline in platelet numbers. However, the researchers added, the side effect is likely to be self-limiting as normal bone marrow has the capacity to compensate by increased platelet production. In add...JCI table of contents -- March 22, 2007
... NEPHROLOGY: Disease-causing genetic mutation reveals its molecular secrets Pseudohypoaldosteronism type 2 (PHA2), also known as Gordon syndrome, is an inherited disease that causes high blood pressure and high levels of potassium in the blood. Recent studies have identified mutations in two genes (W...Story tips from the Department of Energy's Oak Ridge National Laboratory, March 2007
...d in Geophysical Research Letters (Vol. 33, 2006), reveals connections between this index and river flows in the tropics and subtropics that are 20 percent to 70 percent higher than what has been suggested by the linear equations typically employed, according to the paper whose lead authors are Shiraj Khan a...Researchers identify molecular basis of inflammatory bowel disease
... causes severe intestinal inflammation in mice and reveals a molecular mechanism that is likely to also underpin human inflammatory bowel disease. Our gut is home to an enormous number of bacteria, which live in harmony with us and help in food digestion. If they penetrate the wall of the intestine, however,...500,000 years of climate history stored year by year
..., Prof. Litt says. The composition of the ash even reveals which nearby volcano it originates from. Chubb...can be trapped. Under the microscope the fine dust reveals a very special kind of beauty. The pollen of yarrow is as prickly as a hedgehog, the pollen of pine ...Alien predators are more dangerous than native predators
...coyotes down to rats were included. The research reveals that alien predators have done the most damage in Australia, whose native fauna have long been protected by the continent's geographic isolation. According to the World Conservation Union, Australia has nine of the world's 14 worst invasive mammals (...New technologies coming too fast for Indian farmers
...ose to 62 percent from 12 percent.Stone's research reveals that the increase resulted not from traditional farming methods of testing seed for efficacy, but from a pattern of "social learning" farmers relying on word of mouth to choose seeds. "Very few farmers were doing experimental testing, they were just...Race affects tobacco absorption in children
...f the American College of Chest Physicians (ACCP), reveals that African American children with asthma, who are exposed to ETS, have significantly higher toxin levels when compared to their Caucasian counterparts. "African American children suffer from higher rates of tobacco-related disorders, such as asth...Smithsonian scientists report new carbon dioxide study
...ivity within each type of soil. Their study reveals that added CO2 has a so-called "primingeffect," stimulating certain microbes and increasing decomposition.Soils exposed to the elevated CO2 had higher relative abundances offungi and higher activities of a soil carbon-degrading enzyme. As thefungi an...Novel salamander robot crawls its way up the evolutionary ladder
...amandra Robotica. This four-legged yellow creature reveals a great deal about the evolution of vertebrate locomotion. Its also a vivid demonstration that robots can be used to test and verify biological concepts, and that very often nature herself offers ideal solutions for robotics design. The researchers...MIT particles pave way for new bedside diagnostics
...rticle is a fluorescent "dot-pattern" barcode that reveals what the target molecule of the particle is, and the other end is loaded with a probe and only turns fluorescent if the target molecule is present. The particles can also be designed to each test for multiple targets, by adding several unique regions...Location, location -- Cell sizes, lives influenced by host size
... seem to be "one size fits all." Now a closer look reveals that whether a cell lives in an elephant, mouse or something in between can make a big difference in its life. Researchers from the University of Florida Genetics Institute, Harvard Medical School and other institutions developed mathematical mode...Insulin -- in need of some restraint?
...he University of Virginia. Vale says the study reveals the "dark side" of high insulin production, the kind that results from over eating and obesity. "Insulin is very effective at lowering blood sugar, and promotes fat storage, preparing the animal for times when food may not be available," he says. "Bu...An architectural plan of the cell
...week's issue of the journal Developmental Cell and reveals remarkable insights into the fine structure of the cytoskeleton as well as its interactions with other parts of the cell. A key component of the cytoskeleton are long, tube-like filaments called microtubules. They are dynamic structures built of cons...Biophysical Society announces new and notable symposium speakers
...st structure of an RNA ligase. This elegant study reveals the mechanism by which RNA is able to copy itself and directly addresses the "chicken or the egg" problem of what came first, proteins or nucleic acids. It is a wonderful contribution to the biophysical literature and represents absolutely fundament...Genome scan for familial autism finds two new genetic links
...y's 13 research centers. "This large-scale study reveals that autism is an extremely diverse condition," Geschwind noted. "Our findings suggest that autism has numerous genetic origins, rather than a single or few major causes." The consortium used gene-chip technology to search for genetic commonality ...New bird, bat species revealed by extensive DNA barcode studies
... known previously to have two forms, yet their DNA reveals two distinct groups split about 2.5 million years ago. "How can you develop strategies to preserve highly different genetic entities if you don't know they're there? Our work is providing the first molecular evidence of some of these splits." The...Newly discovered West Coast arrhythmias cause
...s of decades of atmospheric and oceanographic data reveals that increasingly wild fluctuations in winds and currents appear to account for a series of recent anomalous ocean events -- from repeated low oxygen zones larger than the size of Rhode Island to massive die offs of seabirds. The scientists say that ......alysis of peripheral T cell lymphoma, unspecified, reveals distinct profiles and new potential therapeutic targets AUTHOR CONTACT: Stefano A. Pileri University of Bologna, Bologna, Italy. Phone : 39-051-6363044 ; Fax: 39-051-6363606; E-mail: pileri@med.unibo.it View the PDF of this article at: https:/...