Tag: "revert" at biology news

Muscling in on a deadly cancer

... skeletal muscle cells grown in the laboratory can revert to muscle stem cells. The Utah research found that tumors arising from mature or nearly mature muscle in mice have some characteristics of stem cells. That suggests the "primitive-appearing [rhabdomyosarcoma] tumors may be the result of non-primitive...

Cars, not crops, should be chief targets in reducing greenhouse gases

...owing, and retiring croplands by paying farmers to revert them to grassland or forests. Carbon dioxide has been implicated in global warming because it can trap heat in the atmosphere much like a greenhouse. "We emit a quarter of the world's carbon dioxide emissions into the atmosphere, even tho...

Scientists generate human islet precursor cells in culture

...d human insulin-producing cells of the pancreas to revert to islet precursor cells. These precursor cells are capable of expansion and appear to naturally and efficiently differentiate into clusters of islet-like cells. This work may help to clarify the natural lifecycle of the beta cell and may eventuall...

Discovery offers cancer prevention, diagnosis, treatment hopes

...d type of cell to become cancerous, it must first revert back to stem-cell stage. "In other words," he said, "it has to turn back time. "So what we found is that the human adult stem cell in which the oct-4 gene was expressed was the 'target' cell for the carcinogenic process to begin. In cells in which it...

Yale scientists find microRNA regulates Ras cancer gene

...e Ras protein," said Slack. "The microRNA does not revert a mutated Ras to normal; instead it acts like a brake on an accelerated Ras." Lung cancer currently has a poor prognosis with less than 15 percent of patients surviving five years. The lungs, however, are relatively accessible for inhalation of poten...

Plants defy Mendel's inheritance laws, may prompt textbook changes

... has accepted for more than 100 years, some plants revert to normal traits carried by their grandparents, bypassing genetic abnormalities carried by both parents. These mutant parent plants apparently have hidden templates containing genetic information from the preceding generation that can be transferred ...

Using nanoparticles, in vivo gene therapy activates brain stem cells

...ne therapy always carry with them the potential to revert back to wild-type, and some human trials have even resulted in fatalities. As a result, new research focuses increasingly on non-viral vectors, which don't carry this risk. Viral vectors can be produced only by specialists under rigidly...

Jefferson biologist coaxing human embryonic stem cells to make dopamine with simpler, faster method

...ion. Dr. Iacovitti decided to stop the process and revert back to an earlier developmental stage. Shortening the differentiation process is important, she notes. The longer cells are grown and allowed to mature in culture before transplant, the less able they are to survive harvest for transplant. "We tra...

Model identifies genes that induce normal skin cells to become abnormal

... the melanoma microenvironment caused the cells to revert to their original appearance. "There were no significant genetic changes between normal skin cells grown on an untreated matrix and those exposed to a matrix preconditioned by human metastatic melanoma cells, further supporting the hypothesis that "...

Stem cell microenvironment reverses malignant melanoma

...lly approved) induced metastatic melanoma cells to revert to a normal, skin cell-like type with the ability to form colonies similar to hESCs. The researchers also showed that these melanoma cells were less invasive following culture on the microenvironments of hESCs. "Our observations highlight the potent...

UCSF study finds nerve regeneration is possible in spinal cord injuries

...st. If we wait too long after an injury, the cells revert back to their normal, no-growth state. Plus, scar tissue begins to form, making growth difficult." "These findings give us hope. The nervous system is capable of being modified to a level where we can achieve nerve fiber growth. Ultimately, the goal ...

Cloned stem cells prove identical to fertilized stem cells

...ll tissue-specific memories from the skin cell and revert it into a genomic blank slate. But this entire process is almost never perfect, and nearly all cells in a cloned blastocyst retain some memory of their original source. As a result, the developing fetus inevitably has some degree of genetic abnormal...

Crossing the Valley of Death: Moving science into practice and policy

...ew "state" and stays there. The ecosystem does not revert to its previous condition. This model better explains how former grasslands may change to shrublands when subjected to intense grazing under certain climate regimes or why some heavily logged areas may convert to a moor rather than return to forest. ...

Sociality of sweat bees evolved simultaneously during climate change

... in which members of the lineage are now unable to revert back to a solitary condition. These insects, however, seem to be able to revert fairly easily," he concluded. Halictid bees, which are important native pollinators in the Northern ...

Minimal genome should be twice the size, study shows

...riment by deleting the alternative, the genome can revert to the original gene instead. "Using the knock-out approach you could infer that both genes are expendable from the genome because there appears to be no deleterious effect in both experiments. "In fact, because there are alternative pathways to the...

Teasing out tissue from blood

... beta islet cells of the pancreas. The idea is to revert a patient's blood cells to the stem cell stage and then chemically nudge them to re-specialise into particular tissue types that can be implanted to heal damaged tissue. A huge advantage over using donated tissue is that the transplant would be "auto...

Finding a cellular Neverland: How stem cells stay childlike

...1 out of the game and Nanog in full control, cells revert to their forever-young state. "We found that in suitable conditions, differentiated cells are still capable of producing stem cells as descendants," says Suzuki. "The molecular mechanisms that we identified here might be used to regenerate stem ...

How purple corn and RNA break genetic laws

...reen, rather than being deep purple. "It cannot revert -- it's a one-way street," said co-author Lyudmila Sidorenko, an assistant research scientist in Chandler's lab. Chandler and her colleagues wanted to know how the B' allele changed B-I's behavior without actually changing B-I's DNA. They already ...

MIT engineers probe spiders' polymer art

.... Like a cooked egg white, dry spider silk doesn't revert to its former liquid state. What started out as a water-based solution becomes impervious to water. The silk protein's long molecules are like tangled spaghetti. They form a viscous solution but are slippery enough to slide past each other easily an...

Microbe fixes nitrogen at a blistering 92 degree Celsius

...m deep in the earth to cause the fixed nitrogen to revert to its gaseous form. Venting water hotter than 30 C contains very little nitrate so organisms in areas where the subseafloor temperatures are higher would lack nitrogen in a form they can use. The discovery of FS406-22's nitrogen fixing capabilities ...

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(Date:8/21/2014)... (ANU) team has successfully replicated one of the crucial ... powered by sunlight which could manufacture hydrogen as a ... It is an exciting prospect to use them to ... Dr Kastoori Hingorani, from the ARC Centre of Excellence ... Biology. , Hydrogen offers potential as a zero-carbon replacement ...
(Date:8/20/2014)... 2014 George E. Fox, a John and Rebecca Moores ... (UH), was named a fellow in the International Society for ... Fox is one of four members two from the ... as fellows in 2014. Fellows are elected every three years, ... 500 members from more than 20 countries, the ISSOL includes ...
(Date:8/20/2014)... University of Tennessee, Knoxville, research finds life can persist ... professor was part of a team that examined waters ... Antarctic ice sheet and found the extreme environment supports ... by Jill Mikucki and her colleagues has implications for ... in the solar system. The findings are published in ...
Breaking Biology News(10 mins):Water and sunlight the formula for sustainable fuel 2UH professor named fellow by International Astrobiology Society 2University of Tennessee research uncovers subglacial life beneath Antarctic ice sheet 2
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