Glucose triggers brain cell death in rats after hypoglycemic coma
...mic coma is to give lots of glucose, fast. But our rodent model makes it clear that overshooting glucose lev...d NADPH oxidase as agents of oxidative stress in a rodent model of ischemic stroke. "So far, the results are very promising," he says....First demonstration of muscle restoration in an animal model of Duchenne muscular dystrophy
...e, and to induce restoration of muscle function in rodent muscles.......known until this paper. Using detailed models of rodent and squid axons and stochastic simulations, the authors performed experiments, now published in PLoS Computational Biology, which took several months to simulate a few milliseconds of real time in the brain. They show how conduction along such thin a...Antidepressants stimulate new nerve cells in adult monkeys, may have implications for humans
...nical relevance of changes in neurogenesis seen in rodent models." Perera and the team treated a group of monkeys with electroconvulsive shock (ECS), an animal version of the highly effective clinical antidepressant electroconvulsive therapy. They saw an increase in new nerve cells in the hippocampus. Ov...Antibody-based therapies effective at controlling malaria
...ficacy of human antibodies can be determined using rodent malaria parasites transgenic for P. falciparum antigens in mice and humans. An in vivo mouse model has significant advantage over the use of new world primates, the only other model for human malaria, which are labor-intensive and difficult to reprod......tin, contribute to the characteristic asymmetry of rodent incisors, which are covered by enamel only on their labial (front) side. Subtle variations in this or related regulatory networks may explain the different regenerative capacities and asymmetric development of various organs and animal species....Does stimulant treatment for ADHD increase risk of drug abuse?
...these studies were done in healthy animals, not in rodent models of ADHD. All experiments were conducted in conformity with the National Academy of Sciences Guide for Care and Use of Laboratory Animals and Brookhaven National Laboratory Institutional Animal Care and Use Committee protocols....News tips from the Journal of Neuroscience
...entous network in the act, the authors immobilized rodent CA1 hippocampal slices by high-pressure freezing. Cryosubstitution and embedding preserved the architecture of the protein network. Electron tomography images were then reconstructed for a three-dimensional view. Within presynaptic boutons, filaments...Stressed-out African naked mole-rats may provide clues about human infertility
Lyon, France: A tiny, blind, hairless subterranean rodent that lives in social colonies in the harsh, semi-arid conditions of Africa could shed light on stress-related infertility in humans, the 23rd annual meeting of the European Society of Human Reproduction and Embryology will hear. Dr Chris Faulkes, a...'Virtual' mouse brains now available online
...s -- one from a normal animal and the other from a rodent missing a gene linked to mental abnormalities -- seem to assemble themselves before the viewer's eyes, structure by structure. Watch the video with Johnson at http://realmedia.oit.duke.edu/ramgen/news/brain_imaging.rm (RealMedia) or http://quick...Research study describes the role part of the brain plays in memory
...was carried out with experimental rats. When one rodent sniffs another rodent's snout right after the second one has eaten, the first one will later choose to eat the same exact food. Animals learn to remember what their congeners eat and, in that way, lower the risk of eating new foods that could be harm...