Study identifies a common genetic risk factor for colorectal and prostate cancer
...is same chromosomal region as playing a predictive role relative to the risk of developing breast cancer.) For the current colorectal cancer study, the USC team genotyped six of the seven variants previously identified as increasing the risk of prostate cancer development. The samples analyzed totaled ...Size and positioning of floral anthers facilitates
... on the functional architecture of flowers and the role of development in floral evolution. Charles Darwin, who observed closely the productions of breeders of pigeons, dogs, and flowers, understood that explaining the evolution and diversity of living organisms, from mosses to elephants, would require...Climate change reduces Queensland's bat numbers
...ss of diversity. Bats play an important ecological role as natural insect control agents. They account for almost a quarter of all mammal species and are the only flying mammals. Bats are declining worldwide and any information about their ecology is crucial to their future management Bats are often excl...Soil particles found to boost prion's capacity to infect
... learn about routes of prion transmission, and the role of soil is just beginning to be explored. "Soil is a very complex medium and we don't know what the agent is binding to" in natural or agricultural settings, Aiken says. "We do know that soil is not the only way it transmits. Animal-to-animal tran...NIEHS researchers identify enzyme critical in DNA replication
...report an important discovery about a critical new role that an enzyme called DNA polymerase epsilon plays...bakers yeast, DNA polymerase epsilon has a primary role in replicating the leading strand of DNA. DNA polymerase epsilon was found to be a key determinant ...Specific type of cell death may accelerate decompensated heart failure
... is a highly regulated process that plays a normal role in cell function. It appears to be an adaptive res...er muted or amplified. Researchers then tested the role of autophagy by inducing heart failure in mice with the varying autophagic responses. Mice with a...Tracing Parkinson's lethal mechanism
...ed that the action of Cdk5 on Prx2 plays a pivotal role in the neuronal damage from MPTP. Importantly, t...idence that the loss of Prx2 activity also plays a role in human PD. They found reduced Prx2 activity in brain tissue from PD patients. These findings pro......nterior cingulate cortex, which plays an important role in executive functions such as attentional control. These structures are located deep in the brain in the region of connection between the two hemispheres. Indeed, the researchers fMRI scans indicated that the rACC is, indeed, the brain center thro...University of Cincinnati receives $1.7M to research molecular treatment of brain injury
... degeneration, Strauss says. We think this plays a role in impairment not only after trauma, but also after other brain injuries, including strokes, seizures and the chronic neurodegenerative conditions like Alzheimers disease. Strauss hypothesizes that manipulating the chemistry of the injured brain c...New 'asthma gene' could lead to new therapies
...ed (ORMDL3) would be a gene with a well-understood role in allergic responses, but that is not what we found," said Abecasis, noting that the gene has no known relation to allergic responses. Asthma, a complex disease caused by a combination of genetic and environmental factors, is the most common chro...Researchers identify genetic mutation that may alter tumor cell proliferation
...s to cause tumor cell proliferation and may play a role in making cells resistant to certain types of ther...lthough AKT1 is central to pathway activation, its role in cancer has been that of an intermediary between mutated upstream regulatory proteins and downstre...Link between immune system and mammary gland could shed new light on breast cancer
...BBSRC), found that cytokines, which have a central role in immune response, are used in the breast to prom...ientists were able to conclusively demonstrate the role of the Type 2 cytokines. When the signalling molecules were not present, production of milk producin...Alzheimer's prevention role discovered for prions
A role for prion proteins, the much debated agents of mad...n the different conditions. They found an apparent role for normal prion proteins in preventing Alzheimers disease. Our experiments have shown that the n...New clue why MS affects African-Americans differently than Caucasians
... the immune response system, which plays a central role in MS, said study author John R. Rinker, MD, with the Washington University School of Medicine in St. Louis, MO, and member of the American Academy of Neurology. Rinker says the reason for this biological difference is unknown, but may be related ...JCI Table of Contents -- July 2, 2007
...that a protein known as dysferlin plays a critical role in repairing the plasma membranes of cardiac muscl...tion of AHSP as a unique hemoglobin helper and the role it may play in diseases in which alpha- or beta-globin production is altered. TITLE: An erythroid ...CU researchers solve mystery of how DNA strands separate
...he current issue of the journal Cell, examined the role of an enzyme called a helicase, which plays a major role in separating DNA strands so that replication of a single strand can occur. Scientists have known th...New approach to pulmonary hypertension shows promise
...y've made a breakthrough in their discovery of the role that nuclear-factor-of-activated-T-lymphocytes (NFAT) play in the cause of the disease. The researchers have identified NFAT as a potential controlling element of pulmonary hypertension in both human tissues and animal models. When it is working pr...M. D. Anderson team identifies new oncogene for brain cancer
...er, M.D., Ph.D., shows that IGFBP2 plays an active role in the tumorigenesis of astrocytoma and oligodendr... identified in a correlation study plays an active role in tumorigenesis. It also permits the delivery and study of combinations of genes. They found tha...Marine worm opens new window on early cell development
...echanisms, which when compromised in humans play a role in many forms of cancer. Their research, appear... UO report suggests an ancient metazoan origin and role for beta-catenin protein in the earliest stages of cellular development. The findings, Bowerman s...Cell receptor may lead to new 'biomarker' for pancreatic cancer
...eral cancers -- including breast cancer -- but its role in pancreatic cancer was unknown. This is one of t...ighly metastatic cancer -- and whether it played a role in disease development. For the UC study, researchers used the protein HGFL (hepatocyte growth fa...