Doing nature one better: Expanding the genetic code in living mammalian cells
... the diameter of the flexible head plays a crucial role in the fast inactivation of this channel, adds Slesinger. ...New method for reading DNA sheds light on basis of cell identity
...vity. Bivalent domains had been noted for their role in ES cells, helping keep these cells developmental options wide open. But with the new genome-wide chromatin data, the scientists discovered that these domains also function in more specialized kinds of stem cells. In neural stem cells, for example,......count and impaired their motility. If MIF has a role in infertility, Dr. Al-Abed and his colleagues are...t was only recently that scientists discovered its role as a pro-inflammatory substance. MIF has now been linked to many autoimmune and inflammatory disease...Modern brains have an ancient core
...ons are among the most ancient neuron types. Their role was likely to directly convey sensory cues from the ancient marine environment to changes in the animals body. Over time these autonomous cells might have clustered together and specialised forming complex brain centres like the vertebrate hypothalam...Critical protein prevents DNA damage from persisting through generations
...mage has been found to play an even more important role in protecting the cell's offspring. New research b...o the researchers began to look into the potential role of V(D)J recombination. "We were not expecting it to be responsible for the breaks we were seeing," ...Breast cancer prognosis runs in the family
...ty and hormone replacement therapy probably play a role in the incidence and outcome of breast cancer. Dr Hartman says the findings are relevant to women with newly diagnosed breast cancer, and to those treating them. The next step will be to understand what is inherited; tumor biology, response to therap...UCF professor finds bacterial pathogen may be key to understanding cancer development
...that a human protein called CrkII plays a critical role in stimulating internalization of Listeria by somehow controlling the cytoskeleton. Listeria is a potentially deadly pathogen, causing abortions in pregnant women and meningitis in those with compromised immune systems, resulting in about a 25 per...Loss of cell's 'antenna' linked to cancer's development
... metastasis, HEF1 and Aurora A, have an unexpected role in controlling the temporary disappearance of cili...scientists increasingly suspect that it may play a role in timing the cell division process. Commonly, cancer cells have entirely lost their cilia, and this...New genetic test developed at Emory advances detection and diagnosis of muscular dystrophy
...accelerated, resulting in more knowledge about the role of the dystrophin gene and an increased understanding about what happens to a muscle cell lacking the dystrophin protein. Researchers around the world are investigating a number of different treatment strategies, all with the goal of slowing or stopp...Early environmental exposure may accelerate age-related neurodegeneration
...tance of the study is that it points to a possible role of common mechanisms triggered by iron and paraqua...sure during the neonatal period may play a crucial role in the development of late-onset PD. Future studies are likely to explore the role of antioxidant...Scientists discover role of enzyme in DNA repair
...cs Inc. have made an important discovery about the role of an enzyme called ataxia telangiectasia mutated protein (ATM) in the bodys ability to repair damaged DNA. NIAMS and NCI are part of the National Institutes of Health (NIH). When DNA within a cell is damaged, the cells protective mechanism must do...Damon Runyon names new class of rising stars in cancer research
...tudies, La Jolla, California, is investigating the role of gene gates or nuclear pores in tumor formation ...iversity, Stanford, California, is deciphering the role of newly discovered small RNAs in the regulation of the hepatitis C virus, a novel approach with imp...Double honors for diabetes researchers
... These studies suggested many genes could play a role in converting the effects of high glucose into ner...betes. Further investigation confirmed the precise role these genes played. Dr Abbotts clinical research into the condition involved identifying the most ...Gene variant increases risk for alcoholism following childhood abuse
...houni, M.D. This finding underscores the central role that gene-environment interactions play in the pathogenesis of complex diseases such as alcoholism, adds NIAAA Director Ting-Kai Li, M.D. A report of the study appears in the June 26, 2007 advance online publication of Molecular Psychiatry. Previo...Story ideas from Molecular & Cellular Proteomics
...llular Proteomics (Vol. 6, No. 6): Proteins role in coronary heart disease Improving colorectal ca...ay to look at protein interactions Proteins role in coronary heart disease Scientists provided the first large-scale identification of the protein...Cancer research specialist and HSPH professor awarded Medal of Honor from WHO cancer agency
...ht on a host of other health issues, including the role of the Mediterranean diet in decreasing cancer and heart disease risk and increasing longevity. His current main research interest is the evaluation of the hypothesis that hormone-dependent breast cancers have their origin in intrauterine life. Th...CSIRO scientists have played a key role in discovering that bats are the likely host of a new virus that can cause a serious but apparently non-fatal respiratory tract illness in humans. As reported today in the internationally renowned journal Proceedings of the National Academy of Scie...ORNL-led team wins DOE bioenergy center
...oud that Oak Ridge will continue to play a leading role in addressing one of the nations biggest scientific challenges. Tennessee Gov. Phil Bredesen noted that the DOE award comes two weeks after approval by the state legislature of a $61 million package for bioenergy research at ORNL and the University...DOE Joint Genome Institute secures long-term lease on production genomics facility
...g other plants and microbes that will play a major role in improving our energy future. In addition, DOE JGI researchers are serving to inspire the next generation of scientists and engineers through the thousands of local high school students who have toured the facility over the years. We look forward ......etween force and fit have a significant, important role in both morphologies of snails and snail predators in evolution, said Konuma. ...