Genome of Clostridium botulinum reveals the background to world's deadliest toxin
...iotics. It lives either as a dormant spore or as a scavenger of decaying animal materials in the soil, and doesnt interact with human or other large animal hosts for prolonged periods of time. Occasionally it gets into a living animal, via contaminated food or open wounds, leading to infant botulism or wound...Botulism bug has few genome wrinkles
...iotics. It lives either as a dormant spore or as a scavenger of decaying animal materials in the soil, and doesn't interact with human or other large animal hosts for prolonged periods of time. Occasionally it gets into a living animal, via contaminated food or open wounds, leading to infant botulism or woun...Burroughs Wellcome fund awards $8.25 million in grants to physician-scientists
... Medicine Deficiency of the lipoprotein receptor, scavenger receptor class B type I, in women with infertility Norman E. Sharpless, M.D. University of North Carolina-Chapel Hill The p16INK4 a tumor suppressor in stem cell aging Warren D. Shlomchik, M.D. Yale University Memory T cells for improved im...JCI table of contents -- March 1, 2007
... other related proteins (all of which are known as scavenger receptors) in humans because of the extensive morbidity associated with lung diseases such as asthma and COPD. TITLE: Protection against inhaled oxidants through scavenging of oxidized lipids by macrophages receptors MARCO and SR-AI/II AUTHOR CON...Cells in the lung clear the air to prevent lung damage
... other related proteins (all of which are known as scavenger receptors) in humans because of the extensive morbidity associated with lung diseases such as asthma and COPD....JCI table of contents: September 7, 2006
...ugh the liver. This occurs when a protein known as scavenger receptor BI (SR-BI) on the surface of cells in the liver recognizes cholesterol in combination with particles known as high-density lipoprotein. Mice lacking SR-BI have very high levels of cholesterol and, like humans with high levels of cholesterol,...Newly identified mechanism helps explain why people of African descent are more vulnerable to TB
...t microbes such as TB by producing nitric oxide in scavenger cells of the immune system known as macrophages. H...nate immunity is the rapid immune response of host scavenger cells to recognition of certain patterns of molecules found on pathogens, which has been retained in...US government $20M NIAID grant funds Proteome Systems' 'catalytic scavenger compounds'
...cancer and infectious diseases. "PSL's "catalytic scavenger compounds" are small molecule compounds that show potential in a broad spectrum of therapeutic applications in the neurodegenerative, cardiovascular, and inflammatory areas," said Porges. "They have been shown to prevent various forms of radiation-in...JCI table of contents October 3, 2005
...ine RCT in humans." TITLE: Hepatic expression of scavenger receptor class B type I (SR-BI) is a positive regulator of macrophage reverse cholesterol transport in vivo AUTHOR CONTACT: Daniel J. Rader University of Pennsylvania Medical Center, Philadelphia, PA USA Phone: 215-573-4176; Fax: 215-573-8606; ...US government grant funds PXL 'scavenger drugs' to treat radiation damage
...illion for a period of 5 years. Proteome Systems' scavenger drugs are small molecule compounds that show potential in a broad spectrum of therapeutic applications in the neurodegenerative, cardiovascular, and inflammatory areas. They have, in addition, been shown to prevent various forms of radiation-induced...New imaging technology shown to detect pancreatic inflammation in type 1 diabetes
...ill into nearby tissues, where they are "eaten" by scavenger cells called macrophages. Thus, the MNPs become concentrated at the inflamed site and can be spotted by high-resolution MRI. In their recent study, the researchers applied the MRI-MNP technique to determine whether they could predict which mice woul...JCI Table of contents August 1, 2005
...CULAR BIOLOGY In the debate of atherosclerosis and scavenger receptors, who's right? Atherosclerosis is a resu...ol and fats in the arteries. It was believed that scavenger receptors, including SR-A and CD36, bound to cholesterol, leading to its uptake, and that this was a...How HDL keeps the heart healthy
...terol by binding to a receptor in the liver called scavenger receptor-BI (SR-BI). However, the signaling events between HDL and SR-BI that afforded heart healthy benefits were not known. In a study appearing online on March 24, in advance of the April 1 print edition of the Journal of Clinical Investigation,...Wolves alleviate impact of climate change on food supply, finds new UC Berkeley study
...cause wolves ameliorate the effect of weather, the scavenger community will be better able to adapt to changing conditions." The researchers studied 55 years of weather data from Yellowstone's Mammoth Hot Springs and Tower Falls stations. Information on average monthly snow depths and maximum temperatures rev...Researchers tease out one critical role of tumor-suppressor gene
... of mouse embryos bred to lack Rb. Macrophages are scavenger cells -- they eat up foreign material such as bacteria and viruses. In the developing embryo, macrophages bind to red blood cells, and this binding forces red blood cells to lose their nuclei. A mature red blood cell lacks a nucleus. Leone and his co...Gene linked to greater risk of heart disease in type 2 diabetes
...sporting free fatty acids into cells. It also is a scavenger of oxidized "bad" cholesterol LDL at the arterial wall. All are major players in contributing to atherosclerosis -- the dangerous buildup of plaque that can lead to partial or complete blockage of the artery, leading to heart attack or stroke. In the...