Circles of DNA might help predict success of stem cell transplantation
...one of countless combinations. The rings represent sections of DNA cut out of chromosomes during the mixing and matching of genes that are chosen to build a particular receptor. Each T cell uses the resulting combination of genes to make a receptor that lets the cell recognize a specific target. When stimulat...Prior caesarean delivery not linked to increased risk of stillbirth
...e, held February 7-12 in Reno, Nevada. "Caesarean sections have been associated with some pregnancy complicat... a physician consults a woman with prior caesarean sections about her next pregnancy, stillbirth should not be one of the concerns," said Bahtiyar. Fetal dea...Other highlights in the February 16 JNCI
...el, and sulfur concentrations in esophageal tissue sections from residents of Linzhou, China. They found that the risk of developing esophageal cancer over 16 years of follow-up was much lower for subjects with higher concentrations of zinc in esophageal tissue than for those with lower concentrations. Conta...Gene therapy converts dead bone graft to new, living tissue
... whose treatment involves the replacement of large sections of bone. Cancers such as osteosarcoma, one of the ...proteins that govern its health. His team replaced sections of bones in dozens of mice, using both healthy and dead segments, then scanned the surrounding infla...Neuronal 'traffic jam' marks early Alzheimer's disease
.... Goldstein and his colleagues also examined brain sections taken at autopsy from humans with different stages of Alzheimer's disease. They detected the same kinds of swelling in those samples that they had seen in the mice. "This was a small, initial neuropathological study, but we believe that it is signifi...Domesticated pig's wild origin mapped
... and cattle, are extinct. Wild boars inhabit major sections of Europe, Asia, and North Africa. For the first time ever, the study now being published has included DNA samples from wild boars from major parts of its area of habitation. The results have been compared with the DNA profiles of various breeds of ...Silence the gene, save the cell: RNA interference as promising therapy for ALS
...roduced in the cell, where they bind with matching sections of messenger RNA. The cell identifies the resulting messenger RNA strand as faulty and chops it up. As a result, the genetic blueprint isn't delivered and the protein never gets made. "Gene silencing is an example of using "molecular scissors" at it...DNA 'packaging' linked with cancer
...tic material of cancer cells is knotted-up so that sections of DNA are highly protected from outside interference, unlike the DNA of healthy tissue. An enzyme that snips DNA at certain sequences that recur throughout the genome thoroughly chewed up the DNA from normal cells. In contrast, the enzyme only parti...Regular exercise helps protect muscles in elderly from soreness, injury
... in this case, galloping on a treadmill on small sections of skeletal muscle tissue taken from the limbs of retired racehorses. The findings support a "use-it-or-lose-it" philosophy: After 10 weeks of regular workouts, the horses' muscles showed fewer signs of damage caused by exertion, even after the horse...Pulsating ultrasound enhances gene therapy for tumors
...ound in deep-sea invertebrates--was visible in all sections of the tumors exposed to pulsed-HIFU. Tumors not targeted with pulsed-HIFU showed negligible signs of the gene. An analysis showed reporter gene levels to be nine times higher in tumors treated with pulsed-HIFU compared with tumors left unexposed. Re...Researchers drill historic hole in Atlantic Ocean floor
...ed Ocean Drilling Program (IODP) have drilled into sections of the Earth's crust for the first time ever, and their findings could provide new insights about how Earth was formed. Scientists aboard the research vessel JOIDES Resolution, of which Texas A&M University serves as the chief contractor, took almost...Restoring polluted rivers hindered by lack of coordination
...th Carolina Wetland Restoration Program to restore sections of that stream within the city of Durham, N.C., according to its website, http://www.ellerbecreek.org . Bernhardt also noted that the demolition of the Lowell Mill Dam on the Little River in Johnston County, N.C. is scheduled to begin on April 28, 2...Small species back-up giant marsupial climate change extinction claim
... 45,000 years ago," says Mr Price. "Other younger sections have a mixture of both large and small species that are habitat generalists or are species found in open areas, suggesting the landscape was evolving towards open grassland. "By the latest Pleistocene species dependent on wetter conditions disappear...Once given 'no respect,' cells' tiny RNAS take driver's seat
...a result, the cell breaks the RNA into pieces. All sections except the microRNAs, just 21 to 23 building blocks long, is discarded. The microRNAs can bind to single-strand messenger RNAs of the right sequence, which at the very least interferes with their ability to be read to make proteins and sometimes lea...Steven M. Larson named recipient of SNM's 2005 Georg Charles de Hevesy Nuclear Pioneer Award
...several governmental advisory committees and study sections at the NIH, the Department of Energy and FDA. He currently serves on the Biologic, Environmental Research Advisory Committee (BERAC) of the Department of Energy and the Advisory Committee of the Department of Life Sciences for Brookhaven National Lab...High-powered gene profiles provide clues to genes involved in common form of lung cancer
...ology that makes it possible to zoom in on smaller sections of cell chromosomes than ever before, researchers at Dana-Farber Cancer Institute have identified nearly 100 chromosome regions where genes are either over-copied or missing in non-small cell lung cancer. The findings provide new clues about the loca...Scripps research scientists discover new key to pulmonary edema in respiratory distress syndrome
... facility. They applied fluorescence microscopy to sections of tissue that had been exposed to sphingosine 1-phosphate and showed that the leakage occurs because the activation of SIP 3 receptor signaling causes disruptions in the integrity of the tight junctions between epithelial cells. Electron microscopy...U-M scientists discover identifying markers for primitive blood-forming stem cells
...hem see hematopoietic stem cells in stained tissue sections from mouse bone marrow and spleen, something that was not possible with existing markers. Knowing where primitive hematopoietic stem cells hang out in blood-forming organs will give scientists important clues to how they work, according to Morrison. ...DNA scans reveal possible location of lung cancer genes
...ing institutions have found something much larger: sections of the chromosomes of lung cancer cells where cancer-related genes may lurk. In a study in the July 1 issue of the journal Cancer Research, the researchers used single nucleotide polymorphism (SNP) array technology, which focuses on the building blo...Oceanographers work a quarter of the world away from ship they're 'on'
...ented overviews of large areas of the seafloor and sections of major hydrothermal structures seen previously only in very limited glimpses." Other science firsts accomplished or planned for the July 23 to Aug. 1 expedition include: Learning whether the microbes in the mantle rocks beneath Lost City are res...