Solving sleep problems helps epileptic children
...oblems. UF scientists found no correlation between seizure frequency and behavioral problems. Epilepsy alone ...e whether treatment of sleep disorders will reduce seizure frequency and severity, and to more fully understand the effects of sleep disorders on children's be...UCSD research reveals mechanism involved with type of fatal epilepsy
...r the first decade of life, followed by an initial seizure in the second decade, progressively worsening seizures, early dementia, and death within 10 years of onset. Medications can ease the severity of initial symptoms, but there is no long-term treatment or cure for the disease. A puzzling aspect of the ...Single cell recognition research at UCLA/Caltech finds a Halle Berry neuron
...wired with intracranial electrodes to identify the seizure origin for potential surgical treatment. "Our ability to record directly from the living brains of consenting clinical patients is an invaluable tool for unraveling neural mysteries more efficiently and accurately," Fried said. For the latest study,...An existing diuretic may suppress seizures in newborns
...tive charge and becomes less excitable, inhibiting seizure activity. But in newborns, chloride is already hig...by rats and found that bumetanide indeed inhibited seizure activity, while phenobarbital, as in humans, worked poorly. The study's findings are in keeping wit...Ketogenic diet prevents seizures by enhancing brain energy production, increasing neuron stability
...a chemical messenger in the brain that helps limit seizure activity. They found that GABA levels in the hippocampus were unchanged with the KD. To test whether energy reserves in hippocampal neurons were enhanced with the KD, they counted the number of energy "factories," or mitochondria, within cells usi...How seizures progress to epilepsy in the young
...s to block GABA receptors and/or induce electrical seizure in one hippocampus and analyze whether such manipulations influenced seizure activity in the other. Such a spreading influence is a sign that individual seizures have caused dev...Researchers identify new childhood-onset epilepsy disorder and its genetic cause
...te genetic entities, and the majority of recurrent seizure syndromes remain unexplained. Most, if not all, epileptic disorders can be traced to abnormalities of brain structure or chemistry that alter the electrical activity of nerve cell networks. The children in this study have autistic traits, also though...News tips from The Journal of Neuroscience
... activity, ethanol-induced locomotor activity, and seizure susceptibility, and tried to link the regional expression differences with behavioral phenotypes. Some of the genes that correlated with behaviors were linked to already established quantitative trait loci, thus validating the potential utility of th...Septum keeps neurons in synch, can reduce epileptic seizures by 90 percent
...mportant to understanding the mechanism underlying seizure generation. This line of inquiry could one day lead to the development of anti-epileptic drugs, said Colom. Theta disrupted in epileptic rats In this study, the researchers induced epilepsy by injecting anesthetized rats with pilocarpine, a drug th...Brain's cannabinoid system 'mellows' seizures
...the endocannabinoid system on these neurons and on seizure activity. They used mice as their animal model and... These neurons are known to play a central role in seizure activity. The endocannabinoid regulatory system is also active in another type of neuron triggered b...News tips from the Journal of Neuroscience
...l loss-of-function mutations resulted in increased seizure sensitivity. Why the name kazachoc ? Well, this i...ive (BS) phenotype,a behavior that correlates with seizure sensitivity. And what is a BS phenotype you ask? Well, flies are vortexed for 10 s at high speed, an...Slow brain waves play key role in coordinating complex activity
...oral lobes to precisely localize the source of the seizure so it could be removed in a subsequent surgical procedure. Knight, Canolty and their UC Berkeley colleagues then recorded activity in response to sounds and visual stimulation. Several hours of data from five different patients revealed that high-g...Acorda announces positive Phase 3 Fampridine-SR study in people with multiple sclerosis
... discontinuation were anxiety in one subject and a seizure in another subject that was observed during an occurrence of sepsis associated with a urinary tract infection. No deaths occurred during the study. One death was reported for a subject five weeks after the last on-drug study visit. This death occurr...FDA approves new epilepsy indication for Lamictal
...s with established efficacy in a broad spectrum of seizure types, including partial and generalized seizures....us injury, including broken bones, can occur. The seizure will typically last for a few minutes and then be followed by a period of drowsiness, confusion, hea...Louisiana Tech inventors honored for research
...io, with a license to BrainVital for his epileptic seizure control medical device; and Mike McShane and Patrick Grant, with a license to their start-up company AURA for their sensor technology. In the third category, inventors whose inventions have resulted in a regular U.S. patent application were: ...Gene therapy inhibits epilepsy in animals
...bunit to see if this would have an effect on later seizure development. To carry the gene that alters the expression of the protein, they used an adeno-associated virus vector, injected into the rats' brains. The researchers later injected the rats with pilocarpine, a drug that causes status epilepticus (SE...News tips from the Journal of Neuroscience
...lly increase hippocampal GABA release and decrease seizure threshold. In this week's Journal, Chen et al. strengthen the case for depolarization-induced suppression of inhibition (DSI) as the underlying mechanism for these changes. DSI occurs when increases in postsynaptic calcium trigger production and rele...Angelman syndrome deficits rescued in mice
...ne to seizures, the double mutants showed very low seizure susceptibility. Weeber was surprised by the robust results. "We thought we might rescue some of the deficits that we saw in the mouse model," he said. "We had no idea that we were going to rescue basically everything." Although impossible to appl...African carnage -- 1 year's seized ivory likely came from 23,000 elephants
...he Far East from Malawi. It was the second-largest seizure of contraband ivory on record, the largest since t...laughtered to produce the ivory in just the single seizure in 2002. The paper's co-authors are Matthew Stephens, formerly of the UW and now at the Universit......d intracranial electrode arrays in place to assist seizure localization. Voluntary movements of the tongue, hand, or other body parts produced spectral shifts in areas corresponding to the classical homunculus. The authors used the data from 22 subjects to create maps of cortical activity in different frequ...