Tag: "selectively" at biology news

New mechanism links smoking to lung damage

...ing and testing drugs or other mechanisms that can selectively block these unpaired channels offers a novel approach to disease prevention."...

Orangutans' communication resembles a game of 'charades'

...tentionally modify or repeat hand or other signals selectively based on the success or failure of their first attempt, according to a August 2nd study in Current Biology, a publication of Cell Press. We were surprised that the orangutans' responses so clearly signaled their assessment of the audience's compreh...

Penn researchers discover pathway that eliminates genetic defects in red blood cells

...overed a unique molecular pathway that detects and selectively eliminates defective messenger RNAs from red blood cells. Other such pathways known as surveillance pathways operate in a more general way, in many cell types. Knowing how this specific surveillance system works can help researchers better understa...

New aerogels could clean contaminated water, purify hydrogen for fuel cells

...ry from the water: by acting as a kind of sieve or selectively permeable membrane. The unique chemical and physical structure of the gels will allow researchers to "tune" their pore sizes or composition in order to separate particular poisons from the hydrogen stream. "You can put in elements that bind the poi...

JCI table of contents -- July 26, 2007

...n healthy mice, injected, dying cells are normally selectively engulfed and destroyed by immune cells known as dendritic cells, and as such the presence of cell-associated antigens does not trigger an immune response. By contrast, in DT-treated mice that lacked macrophages in the marginal zone of the spleen, the...

Females more prone to brain damage from alcohol abuse

...he PVAMC Research Service, examined four groups of selectively bred mice: two female groups, including one prone to severe withdrawal and one resistant to severe withdrawal, and two similar male groups. Four control groups also were used. Using DNA microarray or "gene chip" analysis, a laboratory process invol...

Scientists a step closer to understanding how anaesthetics work in the brain

...e same team identified that anaesthetics seemed to selectively enhance the regulating action of the potassium channel, preventing the neuron from firing at all meaning the neuron was effectively anaesthetised. The new research has identified a specific amino acid in the potassium channel which, when mutated,...

Researchers witness natural selection at work in dramatic comeback of male butterflies

...bacteria, which is passed down from the mother and selectively kills males before they have a chance to hatch. ...serve." The researchers noted that bacteria that selectively kill male offspring are found among a range of arthropods, so what was seen in this study may not be...

JCI table of contents: July 12, 2007

...tion. The authors found that EPA1 expression was selectively increased at puberty in the hypothalamus in monkeys, rats, and mice. They also showed that the protein product of EPA1 was expressed in neurons involved in the control of reproduction, and that EAP1 activated GnRH. The authors went on to show that in...

New use for a cell toxin found to inhibit survival proteins in cancer cells

...pecies of invasive fish in lakes has been found to selectively inhibit two "survival proteins in cancer cells. Th... to look for small molecules or compounds that are selectively toxic to cells that over express Bcl-2 proteins. Higher expression of the target protein made cells...

New way to target and kill antibiotic-resistant bacteria found

...way. Our discoveries may lead to the ability to selectively kill antibiotic-resistant bacteria in patients, and to halt the spread of resistance in clinical settings, said Matt Redinbo, Ph.D., senior study author and professor of chemistry, biochemistry and biophysics at UNC-Chapel Hill. The study appears o...

Loss of cell's 'antenna' linked to cancer's development

...at small-molecule inhibitors of Aurora A and HDAC6 selectively stabilize cilia, the authors concluded, suggesting a novel mode of action for these clinical agents. Clinical trials of such inhibitors have already begun, so learning more about the mechanisms of their targets is important in understanding how thes...

Neuroblastoma expert reviews progress and challenges in fighting difficult pediatric cancer

...ve isotopes that zero in on neuroblastoma cells to selectively kill those cells with radiation. Other tools include retinoids--biological molecules that hone in on cancer cells, angiogenesis inhibitors that cut off a tumor's blood supply, and tyrosine kinase inhibitors that interrupt a critical step in the tumor...

2 MSU professors spearhead international water project

...-based technologies. Membrane-based technologies selectively remove things such as chemicals and particles from water, said Voice, professor of civil and environmental engineering. They are analogous to filters except they remove things that are smaller and separate on the basis of chemistry and size. Our proj...

Researchers pit novel version of common virus against cancer

...have been engineering relatively benign viruses to selectively infiltrate and deliver genetic materials into more dangerous cells. However, the current generation of mutant viruses under study has limitations. So far, they are proving to be effective only in tumor cells that express certain proteins. The Roche...

Weizmann Institute scientists develop a general 'control switch' for protein activity

...n. This segment is capable of binding strongly and selectively to a particular chemical drug, which affects the activity level of the engineered protein by increasing or reducing it. When the drug is no longer applied, or when it is removed from the system, the protein returns to its natural activity level. As...

CSHL scientists successfully target tumor microenvironment to stop cancer growth

...ng blood vessels that allow cancers to grow. If we selectively blocked the EPCs, tumors were unable to make blood vessels and could not sustain their own growth, said Vivek Mittal, CSHL Assistant Professor. The findings open an entirely new field of research on how vascular progenitor cells control tumor growt...

'Wurst' ensures that the respiratory system works

...absorb substances from their environment. Thus, by selectively taking in salts, the cells are able to draw water from their environment by diffusion. This appears to be the way in which the tracheae are drained. However, if the "Wurst" protein is defective, the whole process will fail: liquid collects in the air...

Tumor vessels identified by unique molecular markers

...l sites. The study also revealed 13 genes that are selectively overexpressed in tumor blood vessels. Although the function of most of the newly identified genes in tumor blood vessels is unclear, many of the genes encode cell surface proteins, making them appealing targets for the development of new therapeutic ...

Ethanol injection helps manage bone metastasis in thyroid cancer patients

... is distributed. Therefore, if absolute ethanol is selectively injected into a malignant tumor, selective destruction of the tumor may be expected," he added. In their study, 12 patients with radioiodine-ineffective bone metastasis from thyroid cancer underwent PEI. More than 50 percent reduction in tumor volume...

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(Date:7/23/2014)... are packed with healthful compounds, and now lab tests ... as prescription anti-diabetic medication, scientists report. In their new ... Food Chemistry , they found that how the herbs ... which compounds contribute the most to this promising trait. ... that in 2012, type-2 diabetes affected more than 8 ...
(Date:7/23/2014)... Basement membrane degradation and blood-brain barrier damage ... and brain functioning. Matrix metalloproteinase-9 is able ... basement membrane around cerebral blood vessels and ... Huilian Hou and colleagues from the First ... Jiaotong University, China induced cerebral infarction in ...
(Date:7/23/2014)... hippocampal region of the brain is important ... However, the underlying mechanisms are unclear. Dr. ... China monitored the activity of hippocampal neurons ... the mechanisms underlying the neuronal responses. Somatosensory ... changed local field potentials into theta rhythm-dominated ...
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