Individual taste receptor variations determine 'classic' PTC bitterness perception
...-fold difference in concentration. These different sensitivities form a bimodal distribution in almost every population examined, and this distribution was interpreted as evidence that simple genetic differences, possibly involving only a single gene, underlie the PTC perceptual phenotype. The result was an 80-yea...Past AACR president Susan B. Horwitz elected to National Academy of Sciences
...rs that different antigenic markers have different sensitivities to Taxol, and may also be related to drug resistance. "Dr. Horwitz is committed to using the knowledge gained in her laboratory to develop therapies to treat human cancer," noted Margaret Foti, Ph.D., M.D. (h.c.), chief executive officer of the Ameri...Scientists create artificial cricket hairs
...generations of hairs, which they expect to deliver sensitivities at least one order better than what has been presented in the paper....Evolution of taste receptor may have shaped human sensitivity to toxic compounds
...atural selection has played in forming our present sensitivities and protecting us from harmful natural chemicals. The research team analyzed the nucleotide sequence of a human gene encoding a bitter-taste receptor that mediates recognition of a class of naturally ubiquitous, but toxic, cyanide-releasing compounds...Quantum cascade lasers key to handheld gas and liquid sensors
...ry compact sensing device, which could provide the sensitivities needed for breath diagnostics." Since the lasers are so small, devices could be made to sense multiple chemicals by simply adding more lasers. For the liquid phase device, researchers use a planar silver halide waveguide, developed at Tel-Aviv Univer...Patents for protein biomarker Discovery
... samples like blood or sputum, offering unrivalled sensitivities and high content data unseen with genomics & transcriptomics. Using software tools developed in-house, the quantitative comparison of hundreds of samples is possible, making the technology suited for biomarker discovery within clinical trials. In co...Breakthrough technology from Pall increases platelet availability and safety
...tic dose. This has resulted in a disparity of test sensitivities as well as underutilization of a valuable blood resource. The new Acrodose PL System enables blood centers to pool individual whole blood derived platelets prior to storage and conduct a single bacterial contamination test with its integrated Pall eB...Multiple genes permit closely related fish species to mix and match their color vision
...r vision in these cichlids. They have measured the sensitivities of the cones to different wavelengths of light and...igment proteins. The seven cone types have maximum sensitivities ranging from the red end of the spectrum right through to the ultraviolet--light outside the range o...Evidence for expanded color vision for some colorblind individuals
...activated by different wavelengths of light. These sensitivities are altered in deuteranomalous colorblind individu... however, it is possible that owing to the altered sensitivities of their cone photoreceptors, deuteranomalous individuals may be sensitive to color differences that...Genes linked to daily flux in drug toxicity
...e a principle that scientists had long recognized: sensitivities to chemotherapies and other drugs vary over the course of a day, Schibler agreed. Although rigorous clinical study is needed, patient outcomes might therefore be improved in some cases by delivering chemotherapies, or perhaps other drugs, in accordan...Early treatment prevents lasting breathing problems in some premature babies
...e in the arteries that supply blood to the lungs), sensitivities to secondhand smoke, asthma, and respiratory infections; neurodevelopmental problems such as cerebral palsy; learning disabilities; impaired growth; and cardiovascular problems. In the United States, more than 10,000 babies develop BPD each year. P...Don't care for broccoli? A receptor gene's variation suggests an evolutionary excuse
...r TAS2R receptor exhibit correspondingly different sensitivities to the bitter compounds phenylthiocarbamide (PTC) and propylthiouracil (PROP), which resemble glucosinolates. In the new work, researchers were able to show that different genetic versions of this same receptor, known as hTAS2R38, specifically deter...Ewwwww! UCLA anthropologist studies evolution's disgusting side
... to produce offspring, who in turn passed the same sensitivities on to us." Across a series of subtle and ingenious studies, Fessler has managed to illuminate the ways in which disgust may have served to protect our ancestors during such biologically precarious situations as pregnancy and to maximize the likeli...Dartmouth professor makes case for ethically universal stem cell lines
...k we can pursue hESC research and also respect the sensitivities of our fellow citizens. Its not impossible to do both, says Green, the Eunice and Julian Cohen Professor for the Study of Ethics and Human Values, and the faculty director of the Dartmouth Ethics Institute. In addition to resolving current debates, h...Dietary calcium is better than supplements at protecting bone health
...nto-Villareal suggests that individuals with dairy sensitivities could consume other calcium-rich food sources such as calcium-fortified orange juice. Dark green leafy vegetables also contain calcium, but it is not as readily absorbed as calcium from dairy sources....