Tag: "sequences" at biology news

New method simplifies search for genetic changes associated with disease

...enetic code found in those regions. With the base sequences from many patients' DNA, scientists can conduct comparisons that highlight the changes most commonly linked to disease, providing them the leads they need to better understand and treat a wide range of disorders. Researchers report in the January iss...

Scientists reveal molecular secrets of the malaria parasite

...constructed a composite of all three rodent genome sequences (P. yoelii, P. berghei, P. chabaudi) by aligning them against the P. falciparum genome to create a whole-genome synteny map of the four species. In collaboration with Leiden University researchers, Carlton's group was then able to generate maps t...

The simple truth: Animal development not as complicated as it seems

...l complexity of different organisms based on their sequences of cell divisions, known in the trade as cell lineages. They compared the known cell lineages of three different nematode worms and a sea squirt with those randomly generated by a computer program. They found that the real embryos did not behave li...

Surprising study reveals how cancer-causing protein activates

... machine smashes the protein into amino acids then sequences these building blocks. The work took nearly two years to complete. Chin said the research provides an important target for drugs in treating breast and prostate cancers that are common in the United States. According to the American Cancer Society, a...

Scientists decipher genome of fungus that can cause life-threatening infections

...rd's Hyman says, "The two new Cryoptococcus genome sequences and their analysis provide many targets for vaccine development and drug discovery." Scientists in the C. neoformans research community - including Heitman at Duke and Jennifer Lodge at Saint Louis University (SLU) School of Medicine say the...

Found: Missing sequence of the human Y chromosome

...ccomplishment, substantial sections of chromosomal sequences were still missing. The Y chromosome, a sex chromo...this sequence exhibited between 95-99% homology to sequences on exactly half (11 of 22) of the other chromosomes in the human genome, including the pericentromer...

Combination therapy boosts effectiveness of telomere-directed cancer cell death

...cer cell to continuously divide. Telomeres are DNA sequences found at the ends of chromosomes that play a key role in controlling the life span of cells. With every cell division, telomeres get a bit shorter until eventually they become so short that the enzymes that copy DNA for cell division no longer work p...

Sinking coastlines may precede large subduction zone quakes

...th Lipps, Scott said, "we started looking at other sequences to make sure that wasn't just a one-off thing. It ...s of foraminfera present indicated three repeating sequences of high marsh transitioning to low marsh as the land began to sink, then tsunami sand without forami...

DNA molecules used to assemble nanoparticles

...A, typically 34-66 bases long, found complementary sequences on other dendrimers and knitted together, forming barbell shaped two-dendrimer complexes with folate on one end and fluorescence on the other end. Folate receptors are over-expressed on the surface of cancer cells, so these dendrimer clusters would ...

American Academy of Microbiology report proposes initiative to interpret genome data

...ss in the field of genome annotation. "The genome sequences that exist today are a great available resource, and the potential impact they represent to us, if annotated accurately, though combined experimentation and bioinformatics, has yet to be explored," says colloquium chair Richard Roberts of New England...

UCI researchers create new technique for speeding development of vaccines

... amounts of data that arrive in the form of genome sequences from many human pathogens," said D. Huw Davies, lead author of the paper and associate project scientist in UCI's Center for Virus Research. "Our technique addresses and removes this bottleneck. Remarkably, in only ten weeks, we can make every protei...

Hominids lose control

...rat. The authors compared the conservation of DNA sequences making up the bulk of gene-regulating elements and found marked conservation in the regulatory regions between mice and rats, but nearly none between humans and chimps. This result suggests that the gene-regulating elements of hominids are subject to...

Novel technology detects human DNA mutations

...target DNA SNP segment between two oligonucleotide sequences to greatly increase detection specificity and sensitivity. One segment identifies any mutations in the DNA and the probe, a highly sensitive gold nanoparticle, creates a strong signal accurately indicating the presence of a specific target SNP. Pro...

University of Arizona receives IBM grant for massive virtual storage system for life sciences data

... life sciences data, including MRI images, genomic sequences and microscopy images. The project has capabilities to scale to petabytes of data and will help the university manage, integrate and access their current repository of digital assets as well as organize and convert non-digitized assets to a digital f...

Genetic regions influencing male sexual orientation identified

...ar genes within these newly discovered chromosomal sequences that are linked to sexual orientation."...

Man and mouse share genome structures

...chromosomal regions, even where the underlying DNA sequences are different. Bernstein and Schreiber began to...rray technology to identify the underlying genetic sequences associated with the tagged chromatin. Next, they teamed up with Michael Kamal, the co-first author o...

Rice genome approaches completion

...000-fold increase in contiguity for the two genome sequences relative to the existing sequence data. The rese...gues report that there is evidence in the rice DNA sequences for a whole-genome duplication event just before the grasses diverged from other flowering plants, a...

Fleshing out the genome

SEATTLE Genomics, the study of all the genetic sequences in living organisms, has leaned heavily on the blu...on to genes that had been termed "hypothetical" -- sequences that appear in the genome but whose biological purposes were previously unknown. The method not only...

Report addresses safety problem in preharvest stage of food production

...ng an accessible international database of genetic sequences for known foodborne pathogens along with new and improved tools for detecting and cataloging pathogens on the farm. The report is based on the findings of a colloquium convened by the AAM in Perthshire, Scotland, in December 2003. Scientific profe...

New RNA polymerase discovered in plants

...idence for a fourth polymerase when analyzing gene sequences after Arabidopsis thaliana , the "laboratory rat" ...ps make siRNAs that then direct DNA methylation to sequences matching the siRNAs. The results were published in Cell online, Feb. 10, 2005 and will appea...

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(Date:10/15/2014)... the 44th Rosenstiel Award for Distinguished Work in Biomedical ... the mechanisms of genomic instability and its implications for ... second alumnus to win the Rosenstiel Award; the first, ... Alt is the Charles A. Janeway Professor of Pediatrics ... an investigator at the Howard Hughes Medical Institute at ...
(Date:10/14/2014)... – Scientists have sequenced the house fly genome for ... might expect from an insect that thrives in pathogen-rich ... Oct. 14 in the journal Genome Biology , ... and of how flies quickly adapt to resist insecticides, ... house flies (Musca domestica) carry and transmit more than ...
(Date:10/14/2014)... of scientists led by researchers at the University ... of Miami Miller School of Medicine (UMMSM) have ... underlying bipolar (manic depressive) disorder, a breakthrough that ... affective disorder, as well as depression and other ... online this week in Nature Molecular Psychiatry ...
Breaking Biology News(10 mins):Brandeis awards 44th Rosenstiel Award to pioneering geneticist Fred Alt 2House fly genome reveals expanded immune system 2Rare genetic disease protects against bipolar disorder 2Rare genetic disease protects against bipolar disorder 3
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