Tag: "sequences" at biology news
Deep thinking: Scientists sequence a cold-loving marine microbe
...ientists overlaid key C. psychrerythraea protein sequences
onto known 3D structures from similar proteins among the diverse bacteria. Like matching up blueprints, this strategy allowed the team to spot any striking distinctions in C. psychrerythraea's amino acid composition, highlighting differences unique t...
Evolution of taste receptor may have shaped human sensitivity to toxic compounds
...t toxic, cyanide-releasing compounds. By analyzing sequences
from a large sample of individuals representing 60 human populations, the researchers found evidence that specific variants of the receptor gene have been strongly favored in the early stages of human evolution. Employing additional gene sequence ana...
Critical step traced in anthrax infection
...k as a chaperone, interacting with the hydrophobic sequences
on the two factors as they unfold during translocation. The researchers demonstrated that the phi-clamp was critical to infection by mutating the region and thereby blocking translocation of the toxin proteins. These recent experimental results exte...
Trapping genes that control flower development
...lant genome. All endogenous genes contain promoter sequences
that determine where and when they will be expressed in an organism. The reporter GUS gene, lacking its own promoter, will only be expressed and produce the GUS protein if it happens to be inserted into the plant genome in the immediate vicinity of a...
New amphibian species result from exploration, not from rule changes
...es from the 19th century to the present. The gene sequences
were no more similar in recently recognized species than in long-recognized species, a result that argues again taxonomic inflation as the explanation for the growth. Moreover, the Mantellidae include few subspecies that could complicate an analysis....
Gene silencing technique offers new strategy for treating, curing disease
...to correct genetic disease by changing mutant gene sequences
back to normal," Dr. Corey said. "Those types of t...er the human body or viruses and bacteria make RNA sequences
like this to control gene expression," Dr. Corey said. So far, the researchers have inhibited the ex...
A bug's life: Exceptional genomic stability yet rapid protein evolution in a carpenter ant mutualist
...The recent surge in the number of microbial genome sequences
available to the scientific community is allowing ...n called "genome streamlining." Additional genome sequences
of bacterial symbionts are needed, however, to more fully understand the biological basis for these ...
Customized gene chip provides rapid detection of genetic changes in children's cancer
...When DNA bases from a sample bind to complementary sequences
on the microarray, they cause fluorescent tags to shine under laser light. This is a signal that a particular gene variation is present in the sample. "We can test DNA from peripheral blood and from the tumor, and we should see a loss of signal in th...
Scientists discover genetic pathway responsible for breast cancer cell growth
...w type of DNA microchip containing the partial DNA sequences
of approximately 19,000 genes. Dr. Gigure's team was able to localize where the estrogen receptor was bound in the genome of breast cancer cells, thereby identifying a large number of genes that respond to this hormone in a single experiment. "This t...
Revelations of rice
...it is one of the most accurate and complete genome sequences
obtained from a higher (i.e. multicellular) organism. The finished sequence reveals that the 12 chromosomes of the rice plant hold some 37,500 genes. A chromosome is a compact bundle consisting of a long, thread-like DNA molecule wrapped tightly arou...
Complete sequence of rice genome announced
...e which may increase yield and productivity. Draft sequences
of rice published previously lacked the coverage and accuracy to permit such discovery. The revelations implicit in the rice genome may enable agricultural breeders to also address other critical issues in rice cultivation. Messing noted that rice c...
International research team announces finished rice genome
...wly complete rice genome builds upon earlier draft sequences
published by private companies Monsanto and Syngen...partnership," these companies donated their genome sequences
to the IRGSP, saving the public consortium both time and money. "Much as the Human Genome Project h...
Feeding the world
...hed rice genome sequence builds upon earlier draft sequences
published by the private companies Monsanto and Sy...rtnership" and added that by donating their genome sequences
to the IRGSP, the companies saved the public consortium both time and money. By enabling scientists...
New technique could alter field of mouse genetics
... of these genes." With a large inventory of genome sequences
in hand, over the last few years many scientists have shifted their attention to determining the function of all of those genes. The strategy is as systematic as the genome sequencing projects -- mutate each gene, observe the consequences, and invest...
Key process in gene regulation occurs in blood platelets, Univeristy of Utah researchers find
...essary genetic information, pre-mRNAs also contain sequences
of code not needed for making proteins. These unnecessary sequences
are excised during splicing. When all the unnecessary sequences
have been spliced out, the spliceoso...
Evolution of life on Earth may hold key to finding life in outer space
... and his team of scientists focus on comparing the sequences
and 3-D shapes of biological molecules. Their research benefits greatly from the many ongoing genome sequencing projects. "We do a lot of what is called bioinformatics, comparing molecules from different organisms," he said. Fox's group recently...
Tips from the Journals of the American Society for Microbiology
...d consensus primers for amplification and specific sequences
for identification, would be extremely useful for the detection of variants and would probably help solve some unexplained cases of encephalitis," say the researchers. (J. Korimbocus, N. Scaramozzino, B. Lacroix, J.M. Crance, D. Garin, G. Vernet. 20...
Genomics reveals mechanism of heat resistance in bacteria
...prove stability. By mapping intracellular gene sequences
from 199 prokaryote genomes onto sequence-related proteins with known three-dimensional structures, they produced structural models which revealed when disulfide bonds are likely to form. A bias was found for disulfides in a set of thermophilic genom...
Public collections of DNA and RNA sequence reach 100 gigabases
...mes, the genetic make-up of entire ecosystems, and sequences
associated with patents. The INSDC has realized th... the two databases, which at that time had to find sequences
in published journal articles and re-key them into the databases, allocated journals to each team to...
Analysis of flower genes reveals the fate of an ancient gene duplication
... both in terms of gene identity and the order such sequences
appear within the chromosome. This kind of preserved gene order is known as genome synteny. In the new work, researchers have used synteny to clarify the evolution of genes essential for the development of floral reproductive organs, stamens and carp...
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