Tag: "sequences" at biology news
Public collections of DNA & RNA sequence data reach 100 gigabases
...enBank currently contribute over 3 million new DNA sequences
per month to the database. More information about ...mes, the genetic make-up of entire ecosystems, and sequences
associated with patents. The International Nucleotide Sequence Database Collaboration (INSDC) has re...
First production of human monoclonal antibodies in chicken eggs published in Nature Biotechnology
...the genes encoding the antibody and the regulatory sequences
restricting its deposition to egg white. The stem cells were then introduced into chick embryos. At this stage of development, the embryonic stem cells can make significant contributions to the developing chicken. Resulting chimeras with large contri...
New tool to study elusive DNA structure could help reveal better understanding of cancer, diabetes
...eriment using hooks comprised of G-quartet-forming sequences
from the DNA genome, in hopes of catching proteins... plans to apply her technique to G-quartet-forming sequences
that occur in other regions of human chromosomes and have been implicated in cancer, aging, and gene...
IMEx consortium provides new mechanism for improving access to molecular interaction data
...ccessful global collaborations for protein and DNA sequences
and for macromolecular structures. "In deciding to map the biomolecular interactions that define life itself, one quickly realizes how daunting a task we have set for ourselves," says Henning Hermjakob, principal investigator of the IntAct molecular ...
Flipped, expelled, copied, and shrunk
...t these deletions were mediated by short identical sequences
that flank the retroelements. They extended the study to random, non-retroelement sequences
and showed that deletions caused by short identical DNA sequences
were a widespread genomic phenomen...
Newly completed chimp genome helps scientists learn more about human DNA
... genes in 3 billion base pairs of DNA. The current sequences
of the human and chimp genomes are directly comparable over approximately 96 percent of their lengths, and these regions are 99 percent identical. The initial analysis provides the first detailed look at the genetic changes that prompted the chimp-h...
Human Y chromosome preserves itself better than the chimp Y
...res of evolution. After comparing the Y chromosome sequences
of the human and chimpanzee, Howard Hughes Medical Institute researcher David C. Page, postdoctoral fellow Jennifer F. Hughes and their colleagues have seen evidence that the human chromosome has found a way to stabilize itself and survive in the rou...
New genome comparison finds chimps, humans very similar at DNA level
...level, 29 percent of genes code for the same amino sequences
in chimps and humans. In fact, the typical human p...s or other functional areas of the genome. "As the sequences
of other mammals and primates emerge in the next couple of years, we will be able to determine what ...
Delaware scientists make significant advance in study of small RNAs
...ified from diverse plant and animal systems, these sequences
were identified using older technologies that do n...be identified." In addition to the sheer number of sequences
identified, Meyers said "the biggest surprise in the findings is the diversity." He said that their ...
Mammalian transcriptome mapped, and it makes antisense
...er of different regulatory roles, and now that the sequences
of these noncoding RNA molecules are known, scient...'s still unclear whether the majority of antisense sequences
are involved in regulation or in some other biology, he adds, but this result is likely to fuel rese...
Embryonic stem cells accrue genetic changes
...obing changes in the nuclear and mitochondrial DNA sequences
and copy numbers, the researchers examined whether the cells' genetic material had shifts in marks that sit on genes and are passed from cell to cell during cell division. These so-called epigenetic marks -- in this case methyl groups on a gene regio...
Casting a wide net to fight coronaviruses
...mostly on just this virus. But because coronavirus sequences
and structures mutate so quickly, a challenge is to find wide-spectrum vaccines, since a vaccine targeting one strain would likely be ineffective against another. Online this week in the open-access journal PLoS Biology , Haitao Yang, Dawei Ma, Zih...
Solexa and collaborating scientists illuminate the small RNA component of the transcriptome
...ithout requiring advance knowledge of the genes or sequences
of interest. Solexa performed this research in it...wo million short DNA sequences, known as signature sequences
or sequence tags, to identify and quantify both known and novel small RNA molecules. Many regions o...
Human brain is still evolving
...ok the following approach: They determined the DNA sequences
of the two genes among a large number of primate s...ow working to understand how subtle changes in the sequences
of these two genes can alter their function in such a way that would result in favorable selection. ...
Epigenetic activity silences Rb2/P130 gene in lung cancer
... attaching of methyl--or chemical--groups onto DNA sequences
within the tumor suppressing gene Rb2/p130 can cause the gene to cease functioning in non-small lung cancer cells (NSLC) and retinoblastoma cells, researchers at Temple University's Sbarro Institute for Cancer Research and Molecular Medicine and Ital...
Researchers create functioning artificial proteins using nature's rules
... known universe. "How did nature devise the right sequences
that resulted in functioning proteins? Somehow, it...uter program they developed. The program generated sequences
of amino acids, which the researchers then "back-translated" to create artificial genes. Once insert...
Hopkins scientists uncover 'tags' that force proteins to cell surface
...g factory and go to the cell surface. By searching sequences
of known human proteins, the researchers then iden...n internal shipping label. To figure out what tiny sequences
might label the protein for delivery to the cell surface, Shikano added randomly generated eight-bui...
APS physics tip sheet #53
...ng strings of tiny bubbles. The variations in the sequences
result from the interplay between the vibration of gas in the cavity and the rate at which bubbles grow outside of a cavity. These two rates depend on many factors such as champagne temperature and cavity size, but the only factor that changes over t...
Opening the O-box
...onship between the O-box and the other destruction sequences
in the regulation of proteolysis. Dr. Asano adds that "This work identifies a new signal that flags protein for degradation and we are looking forward to finding additional O-box proteins that may play roles in cell cycle control."...
Scientist uses form to explain function of key building blocks of life
...er. "Variants of rubredoxin have evolved different sequences
to transport electrons in the most efficient manner possible," Markley explains. "Different mechanisms have been put forward to explain this, and we wanted to understand how the proteins evolved to have different electron affinities." Markley and hi...
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