Under magnetic force, nanoparticles may deliver gene therapy
...use it efficiently binds and protects DNA in blood serum and delivers it to cells, added Levy. As a nonviral method, it avoids the unwanted immune system responses that have occurred when viruses are used to deliver gene therapy. Levy said his team would pursue further studies into the feasibility of usi...Research shows NPD1 protects a key component of vision
...riggered by another experimental condition, called serum starvation/H2O2/TNF,, would be similarly inhibited. NPD1 also exerted protection in this experimental condition. Addition of NPD1 even eight hours after triggering oxidative stress resulted in protection. In a series of further experiments to delinea...White blood cells are picky about sugar
...,3-glucan. Previous studies indicated that blood serum (basically blood minus cells) helps neutrophils re...n this mixture. She identified several proteins in serum that bind to beta-1,6-glucan, but not beta-1,3-glucan, and then pinpointed a molecule on the surface...Insulin sensitizer also serves as energy-conserving signal to the brain
...ne, leptin, are regulated inversely in relation to serum adiponectin levels, the researchers noted. Thus, central adiponectin/leptin signals may represent the physiological pathway by which hypothalamic AMPK activity and food intake are stimulated during fasting and suppressed after refeeding, they said....New blood test might offer early warning of deep belly fat
...beneath the skin. Moreover, they report that blood serum levels of RBP4 jump in people who are obese, who h...ieve that in the near future, measurements of RBP4 serum concentrations might serve as a novel biomarker for visceral obesity and increased risk for type 2 d...JCI Table of Contents -- July 2, 2007
...red in the spleen to the blood, thereby increasing serum iron levels. This protein or other compounds that ...creasing hepcidin expression and raising liver and serum iron levels. In an accompanying commentary, Jerry Kaplan from the University of Utah School of Med...M. D. Anderson team identifies new oncogene for brain cancer
...rchers note, makes the presence of IGFBP2 in blood serum a potential biomarker that would indicate an active role for Akt in a patients cancer and thus a role for Akt inhibitors in their treatment. The survival of the most advanced stage of glioma, gliobastoma, has not significantly improved for decades,...Noninvasive screening in early pregnancy reduces Down's births by 50 percent
...d. Likewise if there is a certain combination of serum markers in the maternal blood test, taken at the same time, there is the possibility of an increased risk of a chromosomal abnormality. The combined screening is carried out at 11 to 14 weeks of gestation. Professor Brndum-Nielsen and her team loo...New algorithms classify outcomes of nonsmall cell lung cancer patients
...with known outcomes then tested it on pretreatment serum for independent validation and control groups. ...ts to avoid the over-hype seen with previous blood serum biomarkers. Taguchi [and colleagues] should be lauded for their efforts in assessing the reproducibi...The insect vector always bites twice
... evaluate qualitatively and quantitatively, in the serum sampled from human populations living in transmiss...ors, were separated then put into contact with the serum of individual subjects, infected or uninfected, exposed to bites. Comparison of salivary protein imm...New multiple myeloma treatment induced total remission in 33 percent of patients
...alculated by measuring M-protein concentrations in serum and urine. M-protein is associated with myeloma presence. This research work, conducted in the frame of the PETHEMA network, has been coordinated by Hospital Clnic de Barcelona and had the participation of eight more Spanish hospitals: Hospital Ger...A close-up on pancreatic disease: How do we improve the odds?
... [thiobarbituric acid reactive substances (TBARS), serum superoxide dismutase (s-SOD)] and antioxidant status [ferric reducing ability of plasma (FRAP), vitamins A, C and E, erythrocyte SOD (e-SOD), erythrocyte total glutathione (E-TGSH)]. According to the study results, antioxidant supplementation was ...Spotlight on liver disease: Improving today's treatments
...k of CAD, all study participants were measured for serum AST (aspartate transaminase) and ALT (alanine tran... that is independent of the metabolic syndrome and serum C-reactive protein concentration," said Peyman Adibi, M.D., of Isfahan University of Medical Science...Clinical trial data regarding NKTR-061 will be presented at ATS International Conference
... 2a clinical trial evaluating the pharmacokinetic, serum and tracheal aspirate concentration, safety and an...e presented indicating that NKTR-061 achieves safe serum concentrations following multiple dosing in intubated mechanically ventilated patients with gram-neg...PFOA and PFOS detected in newborns
...doctoral research. The researchers analyzed cord serum from 299 newborns delivered at Johns Hopkins Hospital in Baltimore between 2004 and 2005. The samples were tested for the presence of PFOS and PFOA and eight other polyfluoroalkyl compounds. PFOA was detected in all of the samples and PFOS in all but...Treatment-induced growth factor causes cancer progression
...team is currently assessing TGF-beta levels in the serum of patients with breast cancer who are being treat... looking to see in what proportion of patients the serum and tumor TGF-beta goes up, and whether the increase correlates with the inability of the therapy to...New placenta screening for high-risk pregnancies
...elivery. The screening tests include: a maternal serum screening test used to detect Downs syndrome, which measures the hormone levels in the mothers blood; a uterine artery Doppler blood flow test, which checks the maternal blood flow in the placenta; and an ultrasound of the placental shape.Of the 212 ...Laser goes tubing for faster body-fluid tests
...flective tube. The technique tests urine and blood serum for common chemicals important to monitoring and t...ew off measurements when samples of urine or blood serum varied in color. In previous experiments, Berger and his team had explored how a concentration of ea...New reference material for diagnosing kidney disease
...al (SRM) consists of samples of frozen human blood serum certified by NIST for two different concentrations...ical setting, so instead physicians test for blood serum levels of creatinine, a metabolic by-product of muscles. Plugging the creatinine level into an equat......ease the risk of progression, possibly by reducing serum testosterone, researchers say. It is also possible that advanced and localized prostate cancer may be different tumor subtypes, which may react differently to isoflavones. "The present findings provide no clear understanding of when or how localize...