Climate change to bring a wave of new health risks
...al Environment. It will be a dramatic increase in severe weather events - major storms, heat waves, flooding - triggered by a shifting global climate that will wreak most of the human health havoc. "Averages don't kill people - it is the extremes," Patz explains. The issue, Patz says, is how are we going t...UT Southwestern researchers see hope for treating blindness in preemies
...d indeed, when we examined them, we found they had severe retinopathy." Physiologicalstudes using light, c...lop ROP, and of these, 10 percent develop the most severe type, which leads to blindness. Dr. Garcia's work reveals an important mechanism in the development ...Rapid, new test develped for inherited immune deficiency
...dly identifies babies born with inherited forms of severe immune deficiency. The new genetic test, which still must be validated before widespread use, could someday be added to the panel of tests that already screen newborns for a variety of disorders. The test identifies babies born with Severe Combined ...Genome of deadly amoeba shows surprising complexity, evidence of lateral gene transfer
...c amoeba Entamoeba histolytica, a leading cause of severe diarrheal disease in developing countries, include...se liver damage but more often causes dysentery, a severe diarrhea that is often associated with blood in the feces. Unchecked, the diarrhea associated with t...New NIST reference material reinforces fragile-x screens
...oblems ranging from minor learning disabilities to severe mental retardation and autism. The mutation is characterized by an excessive number of repeats of a sequence of three nucleotides (the chemical building blocks of DNA) within a particular gene on the human X chromosome. Proper diagnosis depends criti...Fox Chase Cancer Center scientists identify immune-system mutation
...group of Melvin Bosma, Ph.D., discovered mice with severe combined immune deficiency (SCID), a condition that also affects humans. In addition to providing a unique animal model to study the SCID syndrome, SCID mice have become a highly valuable tool for studying the immune system and are now used by scien...UCI researchers identify trigger for onset of Alzheimer's, aiding search for new therapies
...Starting with mild memory problems and ending with severe brain damage, Alzheimer's usually begins after the age of 60, the risk increasing with age. If no effective therapies are developed, by 2050 it is estimated that 13 million Americans will have the disease. In the United States, five percent of the po...Molecular thermometers on skin cells detect heat and camphor
...mpletely normal behaviorally except that they have severe deficiencies in their ability to detect warm and hot temperatures. Patapoutian and his colleagues also showed that, in cultured keratinocyte cells, TRPV3 is activated by the compound camphor, which is one of the main ingredients in many warming rubs....JCI table of contents April 1, 2005
... XLP patients have normal B cell development but a severe deficiency in the number of circulating memory B cells. This defect was due to impaired T cell help, as T cells from XLP patients had reduced production of the cytokine IL-10 and did not effectively stimulate B cell immunoglobulin production. The res...Pioneering PET/CT research widens applications of imaging for diabetic foot
...r explained that foot infection is one of the most severe complications of diabetes. Diabetes can lead to decreased circulation in one's extremities. This poor circulation--and the reduced ability to fight off minor infections--put diabetics at risk for development of chronic infection involving bone and so...Most older people with mild cognitive impairment have AD or cerebral vascular disease
...e when impaired performance on these tests was not severe enough to warrant a diagnosis of dementia. After death, the investigators measured the amount of Alzheimer's disease pathology and cerebral infarcts (strokes) through brain autopsy. Of the 37 individuals with MCI, more than half (23) met pathologic ...Heart Center cardiologist performs rare liver catheter intervention on teen
...exas Children's Heart Center in Houston repaired a severe liver condition in a 14-year-old male. The doctor used a catheter and septal occluder device that is generally used to close holes in children's hearts. Similar procedures have been reported only six times in medical literature. But this is the firs...Doctors closer to using gene analysis to help trauma patients
...ay. "The vast majority of patients who experience severe trauma or burn injuries actually do well," said Ly...cs as a tool to identify those patients who, after severe trauma and burn injury, will go on to manifest this multisystem organ failure. It's a way to better ...Could microbes solve Russia's chemical weapons conundrum?
...iquid and aerosol form (mustard gas), it can cause severe burns to the skin, and severe damage to the respiratory system and internal organs if ingested or inhaled. It accounts for around ...Oceans more vulnerable to agricultural runoff than previously thought, study finds
...en pollution are becoming extremely widespread and severe as a consequence of the global expansion of industrialized agriculture and the intensification of certain practices," the authors wrote. "Nitrogen-based fertilizers are the primary source of nitrogen pollution, and their use is predicted to double or...Genetic therapy reverses nervous system damage in animal model of inherited human disease
...or AMD, an inherited disease in humans that causes severe mental retardation and skeletal abnormalities. Cats with AMD do not live more than six months. Children born with the worst form of the disease rarely survive into their teens. "Through gene therapy, we replace a 'broken' gene responsible for al...Gene variant increases risk of age-related macular degeneration
...itical for fine, detailed vision. In patients with severe AMD, progressive blurring and loss of central visi...ited States have AMD and 1.5 million have the most severe form," said Postel, the head clinician on the study. "By the year 2030, as the baby boomer generatio...Defenseless plants arm themselves with metals
... thrived in metal-enriched soil, it succumbed to a severe fungal infection when no metal was present. "This difference in salicylic acid levels raises several questions," Salt said. "If you modify other plants so that the level of salicylic acid is always high, those plants are not happy. They look sickly. ...Fasting intermittently reduces cell proliferation, a marker for cancer risk, study finds
...regimen was only slightly less than that of a more severe 33 percent reduction in calories. Until now, scien...at least provides some hope that another option to severe calorie reduction exists." "A five percent reduction in calories would be the equivalent of reducing...Iron exporter revealed that may explain common human disorder
...erroportin only in intestinal cells also developed severe iron deficiency anemia, further confirming the protein's role in iron absorption. The findings offer insight into the underlying basis for hemochromatosis, Andrews said. The researchers propose that, in patients with the disease, perturbations in iro...