Social amoeba sheds light on communication in human brain
...e GABA receptor. "The trick in deciphering complex signals between cells is to find an experimental system that is complex enough to have the signals that are interesting, but simple enough to permit you to test your hypothesis," said Loomis. "Once ...Tiny toads fitted with backpacks
...val 'backpacks' containing radio transmitters. The signals travel up to one kilometre and will allow Browne to locate the toads and to take note of their preferred habitat. Browne began radio-tracking toads at Elk Island National Park east of Edmonton, Alberta last year, and confirming earlier research, was...Fox Chase study shows that weakened T-cell receptor signals change T-cell lineage
...redetermine a cell's fate and whether or not their signals control the choice." In the new study, Wiest and his colleagues use several models to manipulate the signaling strength of the gamma-delta TCR. A strong signal, produced in the presence of a specific binding substance, or ligand, directs immature T ...Data confirm panitumumab single-agent antitumor activity in patients with mCRC
...grow. In fact, many cancer cells actually require signals mediated by EGFr for their survival. Residing on ...f EGFr, which, in turn, triggers internal cellular signals that stimulate tumor cell growth. Panitumumab binds to EGFr, preventing EGF and TGF from binding to ...Fibromyalgia patients may benefit from cough remedy, UF study finds
...the brain and spinal cord - somehow magnifies pain signals to abnormally high levels, said Staud, who is affiliated with UF's McKnight Brain Institute. Central sensitization is associated with wind-up, a phenomenon in which repeated touches - even handshakes or pats on the back - generate lingering pain that...Brain may be less plastic than hoped
...ame sides of the field of vision. The retina sends signals that the brain interprets as light, color, or objects. Each section of the retina corresponds to a specific location in the primary visual cortex. Without any visual signal to interpret, the cortical area corresponding to each monkey's blind spot fe...Retina adapts to light changes by rewiring itself
...p bipolar cell terminals filter the bombardment of signals being sent by photoreceptors to bipolar cells befo...curs during exchanges of amino acids that serve as signals between the cells and has long-term duration: It can last as long as 10 minutes. Until now, the flow...Vampires beware: Scripps scientists describe molecular basis of raw garlic's pungency
...t temperature ranges, and the integration of these signals is the basis of our ability to sense temperature through the skin. When a person's hand touches ice, for instance, the cold channels on the nerve endings embedded in our skin open up, allowing an influx of positively charged calcium ions into the ner...At long last, scientists figure out how plants grow
...complex of auxin, SCF(TIR1) and the repressor that signals enzymes to destroy the repressor, thereby turning on the repressed gene. "The key interaction is between TIR1 and the repressor," Estelle said. "Nihal was able to get that to work in a test tube, but the interaction would only occur if he added auxin...Scientists journey to southern Africa to unravel the secret world of elephant communication
...enerate powerful vibrations in the ground--seismic signals that elephants can feel, and even interpret, via t...s been done showing that small animals use seismic signals to find mates, locate prey and establish territories," she notes. "But there have only been a few st...Edible bivalves as a source of human pathogens: signals between vibrios and the bivalve host.
...s research gives an insight into the complexity of signals that pass between vibrios and bivalve host cells and helps to explain how these processes develop in natural conditions and determine the fate of vibrios in the bivalve host....Decoding the logic of olfaction
... in understanding how the brain translates complex signals from odorant receptors in the nose into odor perce...the Buck and Axel laboratories further showed that signals from neurons with the same type of odorant receptor converge at two specific spots in the olfactory ...Super predators and mass extinctions; extreme NMR; and the world's smallest solenoids
...ignal can cause the nuclei to flip over and create signals that reveal information about the atoms and their environments. This makes NMR spectroscopy an important method for analyzing chemical composition and molecular structure. NMR is also the phenomenon at the heart of Magnetic Resonance Imaging (MRI), ...Scientists use gene transfer technology and common virus to block neuropathic pain
... neurons that transmit pain, temperature and touch signals to and from the brain. Now, scientists at the VA A...n Medical School have developed a way to block the signals responsible for neuropathic pain. The secret to their success is based on a virus called herpes simp...Developing nervous system sculpted by opposing chemical messengers
...use a network of nerves called motor neurons carry signals from the infant's brain and spinal cord to muscles... neurotransmitters) that are responsible for nerve signals are also involved in the wiring of synapses, the network's crucial contact points between nerves, or...From memory formation during sleep to novel components for physics
...rify models to represent the way in which acoustic signals are processed, in order to then explain the mechanisms which are responsible for the exceptional abilities of the human auditory system, such as recognising individuals and understanding what they are saying in a general mass of voices. The objective...Scientists create digital bacteria to forge advances in biomedical research
...chemotaxis system, which transmits the biochemical signals responsible for cellular locomotion. They also have flagella, the whiplike appendages that cells use for propulsion, and the motors to drive them. Emonet and his associates have designed their digital bacterial system in modules, so that additional ...Immune cells' genetic 'jam session' is controlled by cell division machinery
...ly divides. "It was clear that destruction of RAG2 signals the end of active recombination, but whether its decline just happened to coincide with the beginning of DNA copying or whether the two processes were somehow linked was unclear," he says. "Now we have the first biochemical evidence that it's no mere...Discovery suggests why stem cells run through stop signs
...take place, suggesting that microRNAs shut off the signals that stop cell division in most other cells. The findings were published online this week by the journal Nature . In the paper, the researchers also speculate that microRNAs may play a similar role in cancer cells, encouraging their proliferation. ...... of Ras--produced by an oncogene that sends growth signals to a cell--was added to this combination, it produced clinical features of invasive human melanoma: darkly pigmented skin that progressed to ulcerated tumor nodules. Melanoma was observed as early as one month after the oncogenic combination was intr...