Tag: "simian" at biology news

Clues to future evolution of HIV come from African green monkeys

...frican green monkeys shows that an HIV-like virus, simian immunodeficiency virus, or SIV, first infected those monkeys after the lineage split into four species. The new research reveals the split happened about 3 million years ago. Previously, scientists thought SIV infected an ancestor of green monkeys...

Macaque genome analysis will help find human disease genes

...t, Hernandez says. For example, he points out, the simian immunodeficiency virus (SIV) is used as a model for the human immunodeficiency virus (HIV), but when exposed, Chinese macaques develop AIDS-like symptoms more slowly than Indian macaques. An important finding for medical research, Hernandez says, is ...

Analysis of rhesus monkey genome uncovers genetic differences with humans, chimps

...que." The rhesus, because of its response to the simian immunodeficiency virus (SIV), is widely recognized as the best animal model for human immunodeficiency virus (HIV) infection. The rhesus genome sequence will also serve to enhance essential research in neuroscience, behavioral biology, reproductive ...

LSU professors monkey around with the Rhesus Macaque genome

...ir response to infectious diseases such as SIV, or simian immunodeficiency virus, is similar enough to the human reaction to HIV, or human immunodeficiency virus, that these primates serve as a dominant model for disease studies and vaccine development. Because of this, access to the complete macaque sequen...

Jefferson scientists find rabies-based vaccine could be effective against HIV

... HIV, while the other was an internal protein from simian immunodeficiency virus (SIV). They used the latter because HIV does not cause disease in monkeys. The idea was that such rabies vehicles, or "vectors," would help attract a strong response from the animals immune system, though the rabies virus us...

Common mechanisms for viral DNA replication

... far easier to study in the much simpler virus. In simian virus 40 (SV40), the large T-antigen protein (T-ag) is responsible for recognizing DNA sequences required to start replication, called the origin of replication. SV40 T-ag can also cause DNA to melt or unwind. In a new study published online in the o...

Wild gorillas carriers of a SIV virus close to the AIDS virus

... article in the journal Nature, the discovery of a simian immunodeficiency virus (SIV) infection in wild gorillas. Samples of faeces collected from different communities of gorillas found in the remotest areas of the Cameroon tropical forest were found to contain antibodies against this virus, called SIVgor...

HIV gets a makeover

...irus -- known as SIVmac, or the macaque version of simian immunodeficiency virus -- to test potential therap...h vigor. The researchers dubbed their end result simian tropic HIV (stHIV): a form of HIV-1 that only differs from the original by about 10 percent, but can...

Heavy drinking can hasten the progression of the simian immunodeficiency virus disease

...e time to AIDS among rhesus macaques infected with simian immunodeficiency virus (SIV). Alcohol abuse can i...inking can accelerate the progression of end-stage simian immunodeficiency virus (SIV) among rhesus macaques, likely mimicking what happens to humans infected...

Viruses can jump between primates and humans, researchers warn

...at HIV, the virus that causes AIDS, started out as simian immunodeficiency virus (or SIV), and jumped to hum...y temple in Bali, Indonesia, will be infected with simian foamy virus (SFV) from a monkey bite. SFV is a primate retrovirus that so far has not been shown to ...

NHGRI announces latest sequencing targets

...dies. In addition, because it can be infected with simian immunodeficiency virus, a close cousin to the human immunodeficiency virus (HIV), the rhesus is widely recognized as the best animal model for research on Acquired Immune Deficiency Syndrome, or AIDS. It also serves as a valuable model for studying o...

HIV-1's high virulence might be an accident of evolution

...IV-1 Nef protein, and those of its closest related simian viruses, however, lack this protective function, l...at gave rise to HIV-1 and may have predisposed the simian precursor of HIV-1 for greater pathogenicity in humans." "Heightened immune activation is the only ...

AIDS vaccine research offers new insights on survival

...esearch found that among monkeys infected with the simian immunodeficiency virus (SIV) -- 24 of which were vaccinated and six of which were not -- the immunity generated by the vaccine controlled infection for approximately 100 days before levels of virus increased and T-cell counts dropped. But instead of ...

UAB researchers confirm HIV-1 originated in wild chimpanzees

...mparisons to be done between HIV-1 and its closest simian virus counterpart." He went on to say that "finding this cluster of naturally infected chimpanzees will allow us to explore the natural history and behavior of SIVcpz in its natural host and help us begin to unravel how and why SIVcpz made the jump t...

Immune response to HIV in the brain

...led "chronic phase," were unknown-until now. Using simian immunodeficiency virus-infected models in the chronic phase, the research team found both virus and infiltrating lymphocytes (CD8+ T cells) in the brain. Molecular analysis revealed that the expression of several immune response genes was increased, ...

Researchers assemble second non-human primate genome

...r studies. In addition, due to its response to the simian immunodeficiency virus (SIV), the rhesus is widely recognized as the best animal model for human immunodeficiency virus (HIV) infection. It also serves as a valuable model for studying other human infectious diseases and for vaccine research. The ava...

Performing monkeys in Asia carry viruses that could jump species to humans

...a, Indonesia, and tested those samples for various simian viruses. They found that about half of the macaques tested positive for simian foamy virus (SFV), a primate retrovirus that so far has not been shown to cause disease in humans, b...

JCI table of contents September 1, 2005

...vated monocytes contributing to neuronal injury in simian immunodeficiency virus neuroAIDS AUTHOR CONTACT: Kenneth Williams Beth Isreal Deaconess Medical Center, Boston, MA USA Phone: 617 667 2064; Fax: 617 667 8210; E-mail: kenneth_williams@hms.harvard.edu View the PDF of this article at: https://www...

Primate virus jumps species barrier to humans for first time in Asia

...d case in Asia of primate-to-human transmission of simian foamy virus (SFV), a retrovirus found in macaques ... AIDS in humans, is believed to have originated as simian immunodeficiency virus (SIV), and jumped the species barrier to humans when African bushmeat hunters...

Virus uses tiny RNA to evade the immune system

...us that can cause kidney infections in its natural simian host. In rodents, however, it can cause cancer. Although the SV40 genome has been found in some human tumors, its role in human cancer has been debated. The virus is better known as a model system that has greatly contributed to major scientific adva...

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(Date:10/18/2014)... suspected genetic conditions, a certain type of exome sequencing ... than traditional molecular diagnostic methods, according to a study ... released to coincide with the American Society of Human ... protein­coding region of the genome (the complete set of ... organism), has been rapidly applied in research settings and ...
(Date:10/16/2014)... Cancer constantly wages war on the human body. ... a stalemate. In pancreatic cancer, this stalemate—known as ... becoming aggressively malignant, a phenomena that is poorly ... in the laboratory of Salvatore Torquato, a Professor ... the conditions surrounding tumor dormancy and the switch ...
(Date:10/16/2014)... Syncytial Virus causes severe respiratory tract infections and ... year. Scientists at VIB and Ghent University have ... counteract this common virus infection. , Xavier ... that paves the way for the development of ... virus that causes suffering in numerous small children ...
Breaking Biology News(10 mins):Study examines type of exome sequencing and molecular diagnostic yield 2Study examines type of exome sequencing and molecular diagnostic yield 3Modeling tumor dormancy 2New perspectives for development of an RSV vaccine 2
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