OT, VP studied as novel psychiatric drug sources; consider gender-specific drug models
... vasopressin V1a/V2 antagonist conivaptin on serum sodium concentration and effective water clearance in hyponatremia clinical trials."...Researchers make headway in mystery of migraines
...y which our brain cells communicate." By expelling sodium from the cell, and drawing potassium from outside, the sodium pump maintains a gradient of potassium, which is critical for the propagation of electrical signals ...Breakthrough: Structure of membrane protein described by Hebrew University, German researchers
...s and ends at the point at which it binds with the sodium or the hydrogen deep within the cell membrane. Near that point two chains of the protein unite into a unique structure." The researchers believe that this unique structure is the basis for the activity of the protein. The protein operates as a kind ...University of Nevada, Reno research team discovers hormone that causes malaria mosquito to urinate
...quito causes the mosquito to excrete fluid rich in sodium chloride, the main salt in blood. "Only DH31 causes the massive loss of sodium chloride which causes the mosquito to pee," Schooley said. "Stimulation of this process when the mo...TV ads market junk food to kids, new study finds
...n the child-audience ads "would exceed the RDV for sodium and provide nearly a cup of sugar," said Harrison, a professor of speech communication at Illinois and an expert on media effects on children and adolescents. "How many kids actually eat a diet like that, I can't say," she said. "But it's important t...Roadways and parking lots threaten freshwater quality in the northeastern US
... are hardening the watershed and feeding it a high sodium diet that is detrimental to the health of aquatic ecosystems." The changes observed were not subtle. By accumulating in ground water and aquifers, road salt was linked to year-round increases in freshwater salinity. In New York and Maryland, freshwat...Gene therapy to lower blood pressure just enough
...improves the manner in which the kidney eliminates sodium or salt from the body and inhibits other systems, such as the sympathetic nervous system, believed linked to development of high blood pressure. "This makes ANP an attractive agent for use in treating blood pressure," said O'Malley. "However, its u...VCU researchers design new receptor and enhance bioassay to advance drug discovery process
...cessive amounts of electrolytes such as potassium, sodium and chloride, resulting in electrolyte abnormalities. Two potential outcomes of Bartter's syndrome are kidney failure and inner-ear defects resulting in deafness....Hormone might cause dangerous pregnancy complication
...take of a wide range of essential nutrients. The sodium pump contains the target or "binding site" of a gr...ws," said Dr. Lingrel, "and they all worked on the sodium pump binding site."It turns out that almost all species, from fruit flies to humans, have a site tha...New genetic link to high blood pressure found
... surface could alter someone's ability to regulate sodium levels, and therefore blood pressure, Weder explains. The new finding is published by a team that includes Weder and his Tecumseh study team -- but also researchers whose specialties are psychiatry and the genetics of human behavior. Co-author Margi...Modifications render carbon nanotubes nontoxic
...chment of the chemical subgroups hydrogen sulfite, sodium sulfite and carboxylic acid. The cytotoxicity of undecorated SWNTs was 200 parts per billion, which compares to the level of 20 parts per billion identified last year for undecorated buckyballs. The modified nanotubes were non-cytotoxic. While cell d...New discoveries about neuron plasticity linked to learning and memory
...te membrane and allow the passage of potassium and sodium ions into and out of the neuron, are altered during learning. "The h-channels undergo plasticity, not near the synapse but probably throughout the dendritic tree," says Johnston. To record the changes during learning, cells from the rat hippocampus ...Mechanism of new 'sudden-death' arrhythmia detailed
...um exchanger protein (NCX1), which trades incoming sodium for outgoing calcium. The sodium is then pumped out by the protein enzyme Na/K ATPase. Both of these protein "molecular pumps," NCX1 ...A meaty, salty, starchy diet may impact chronic lung disease
...nds that eating mostly meat, refined starches, and sodium may increase the likelihood of developing chronic ...whose diets are rich in meat, refined starches and sodium are 1.43 times more likely to report new onset of persistent coughs with phlegm than those who consu...A salty tale: New bacterial genome sequenced from ancient salterns
...plasm, keeping an osmotic balance against the high sodium chloride concentration outside. That's where evolutionary strategy comes in. Analyzing the bacterium's genome, researchers found that S. ruber's proteins are typically rich in acidic amino acids and relatively poor in hydrophobic (water-repellent) a...Hearing loss from chemotherapy underestimated
...r chemotherapy compounds to tumors, has shown that sodium thiosulfate (STS) decreased hearing loss in patients with malignant brain tumors who were treated with carboplatin chemotherapy, which is given with the blood-brain barrier disruption technique. When STS was given four hours after carboplatin, ototox...Storing carbon to combat global warming may cause other environmental problems, study suggests
...ained. During these chemical exchanges, "you leave sodium behind, which builds up in the soil to make it saltier," he said. Jackson's former postdoctoral scientist Esteban Jobbgy, now at the Universidad Nacional de San Luis in Argentina, and Kathleen Farley of The Nature Conservancy, also investigated anot...Common food preservative might provide treatment for cystic fibrosis
...t susceptible to destruction by slightly acidified sodium nitrite, a common chemical that is widely used in ...re easily destroyed by slightly acidified (pH 6.5) sodium nitrite. Part of the problem with early and chronic cystic fibrosis, Dr. Hassett explained, is that...DNA-wrapped carbon nanotubes serve as sensors in living cells
...s of certain atoms -- such as calcium, mercury and sodium -- the negative charges become neutralized and the DNA changes shape in a similar manner to its natural shape-shift from the B form to Z form. This reduces the surface area covered by the DNA, perturbing the electronic structure and shifting the nano......on contribute to SIDS? The SCN5A gene codes for a sodium channel, a pore found in cardiac muscle cells that controls the passage of sodium ions in and out of the cell. "This seemed like a good candidate for a genetic difference that coul...