Scientists force viruses to evolve as better delivery vehicles for gene therapy
...ells it is ordinarily not good at getting into, or speeding its transport through the body," he said. Though Schaffer acknowledges that the technique could be used to help pathogenic viruses evade the human immune system, potentially making them more virulent, he said that other and easier techniques already ...Thousands of barges could save Europe from deep freeze
...barges moving into the northern ocean in the fall, speeding the initial formation of sea ice by pumping a spray of water into the air, and then, once the ice is formed, pumping ocean water on top of it, trapping the salt in the ice and reaching a thickness of seven meters. In the spring, water would continue...Imaging study links key genetic risk for Alzheimer's disease to myelin breakdown
...ontent allows myelin to wrap tightly around axons, speeding messages through the brain by insulating these neural "wire" connections. As the brain continues to develop in adulthood and as myelin is produced in greater and greater quantities, cholesterol levels in the brain increase and eventually promote the ...Taxpayer advocacy group says Cures Bill is the right medicine
...zes how important the sharing of information is to speeding research and translating new knowledge into cures," said Furlong. "In the age of the Internet, it makes no sense for the results of taxpayer-funded research to be hidden away." The bill calls for DHHS-funded research to be made available in NIH's pop...Fruit fly research set to revolutionize study of birth defects
... a month using readily available scientific tools, speeding up study times while keeping costs low. "It also adds to the growing list of roles fruit flies can take," says Walker. Fruit flies are already used as models for aging, neural disease and cancer....Breakdown of myelin insulation in brain's wiring implicated in childhood developmental disorders
...ontent allows myelin to wrap tightly around axons, speeding messages through the brain by insulating these neural "wire" connections. Bartzokis' analysis of magnetic resonance images and post-mortem tissue data suggests that the production of myelin is a key component of brain development through childhood a...A resetting signal keeps circadian rhythm on track in Drosophila fruit flies
...he Brandeis researchers came to this conclusion by speeding up only the morning cell clock or only the evening cell clock. The results showed clearly that these two clocks always remained coupled in a network that was governed by the morning cell signal. "We think it very likely that something similar is o...Vanadium appears to play role in speeding recovery from infections
...ut just how it works and how it might be useful in speeding recovery. The amount of vanadium used in the study was comparable to that found in nutritional supplements. While its nutritional value is unclear, the body needs an estimated 10 to 20 micrograms a day and obtains it mostly from plant material. Vanad...Researchers to gain wider access to knockout mice
...ortant mouse models into the hands of researchers, speeding advances in the understanding of human disease and the development of new therapies. It also represents a significant step in the direction of launching an international project to systematically knock out all genes in the mouse." Since the early 198...Gene discovery sheds light on causes of rare disease, cancer
...eins that encourage biochemical reactions, usually speeding them up). FANCM apparently provides an engine that moves the FA DNA repair machine along the length of DNA. It also is a key component of the complex that is switched "on" or "off" by phosphorylation, or the addition of a phosphate group to a protein...NIH awards $4.2 million grant to scientists at Scripps Research to speed DNA sequencing technologies
... five-year grant to conduct basic science aimed at speeding the rate at which the next generation of DNA sequencing technologies will become available to scientists and clinicians. This award is part of a larger initiative announced today by the National Human Genome Research Institute (NHGRI), part of the N...NHGRI expands effort to revolutionize sequencing technologies
...search and health care. "The efforts are aimed at speeding the rate at which the next generation of sequencing technologies become available in the scientific lab and the medical clinic," said NHGRI Director Francis S. Collins, M.D., Ph.D. "Not only will these technologies substantially reduce the cost of se...Multi-species genome comparison sheds new light on evolutionary processes, cancer mutations
...ion of mammals into more distinct breeding groups, speeding the development of species-specific chromosomes. "This study has revealed many hidden secrets on the nature and timing of genome evolution in mammals, and it demonstrates how the study of basic evolutionary processes can lead to new insights into the...Genomic sequences processed in minutes, rather than weeks
... Energy's Pacific Northwest National Laboratory is speeding up our understanding of the machinery of life -- bringing us one step closer to curing diseases, finding safer ways to clean the environment and protecting the country against biological threats. ScalaBLAST is a sophisticated "sequence alignment too...Parasite whips up ideas for bowel cancer treatments
... the gut wall. "We were able to counteract this by speeding up the cell 'escalator' artificially but some hosts we studied managed to do this naturally. It's ultimately our genes that determine whether we make the right immune response."...Use of PET can reduce, may eliminate more strenuous drug development trials with animals
...ion time for therapeutic pharmaceuticals, possibly speeding the way for innovative drugs to patients, said Welch. Since there is no public registry of animal researchers, Welch estimates that there may be as many as 12,000 academic and private animal imaging labs in the world and that more than 200 may do sma...University of Pittsburgh gets wired for speed with Apple Xserve G5 cluster
...les in human genetics every day and faster than a speeding FBI-issue bullet. Using the school's newly installed 125-node Xserve cluster, more than 30 investigators and scientific teams, engaged in more than 120 complex research projects have all the computing power they could ask for, according to M. Michael...Carnegie Mellon and U. of Pittsburgh create tool to understand neuron rhythms, learning
...ing neuroscientists whether a neuron is capable of speeding up or delaying its output in response to a stimulus, or whether a neuron only can fire more quickly in response to a stimulus. The CNBC's novel method is the first for estimating PRCs for both these types of neurons. A neuron's PRC also tells researc......out all of their sequences simultaneously, greatly speeding up the process and dramatically lowering the costs. A single slide could provide sequence data about 10 times more rapidly than today's large sequencing centers for about a hundredth of the cost. NHGRI's long-term goal is to cut the cost of whole ge...