U-M scientists see ubiquitin-modified proteins in living cells
...s usual location in the cell's nucleus into hollow spheres called lysosomes in the cytoplasm outside the nucleus. Filled with digestive enzymes, lysosomes break down unwanted proteins into amino acids the cell recycles to make new proteins. "Jun's function in the nucleus is transient and time-depende...Ancient creature fossilized by the bacteria that ate it
...ubacteria. The bacteria look like millions of tiny spheres forming the shape of the arthropod. When he saw the SEM images, Babcock immediately thought of another experiment in his lab. One of his students, for his thesis project, observed how a dead horseshoe crab decomposes in a water tank...MIT team engineers new approaches to understanding malaria, more
...own tool: optical tweezers. With this tool, silica spheres or beads are attached to opposite sides of a red blood cell, and a laser beam is aimed at one bead. Under the right conditions, the laser "traps" the bead, so that the trapped bead can be pulled, stretching or deforming the cell. While others have al...Scientists find common roots for thousands of plant compounds
...ial. Just as a potter can transform five identical spheres of clay into five unique pieces of art, identical precursor molecules can transform into unique compounds by following different molecular pathways. Scientists previously discovered that two independent pathways, located in different compartments wit...Probing the promise and perils of nanoparticles
...n studying nanoparticles known as dendrimers, tiny spheres whose width is ten thousands times smaller than the thickness of a human hair. Dendrimers have shown promise for precisely delivering drugs to their targets inside the body, but high concentrations of these nanoparticles can be toxic. In earlier work...CyberWalk - unconstrained walking in virtual worlds
...ill consist of thousands of small, loosely pivoted spheres - similar to oversized ball-bearings. The spheres are propelled by a treadmill mounted on a turntable. In this way it will be possible to transport a ...Shared computing grid cuts data mountains down to size
...chwartz operate in completely different scientific spheres - one seeking to explore the fundamental properties of matter and the other trying to wrest free the secrets of the human genome - both have the same dilemma: They are awash in a sea of data. To make sense of the human genome, for example, Schwartz a...Catalyst support structures facilitate high-temperature fuel reforming
...open at both ends. A slurry containing polystyrene spheres 50 nanometers to 10 microns in diameter is then al...e slurry reaches the other end of the channel, the spheres begin to pack together as a result of solvent evaporation, and the packing process continues toward ...Self-assembled DNA buckyballs for drug delivery
...earchers have made DNA buckyballs -- tiny geodesic spheres that could be used for drug delivery and as contai...15 nm long. (While still on the nanoscale, the DNA spheres are much larger than carbon buckyballs, which are typically around 7 nm in diameter.) About 70 perce...'Nanospheres' that block pain of sensitive teeth
...conference EMAG-NANO 2005 shows that creating tiny spheres of a ceramic material called hydroxyapatite could ... 40nm in diameter. Earl said: "We found these tiny spheres are really good at filling the channels in teeth, packing inside them quite evenly and going down th...$16 million grant advances nanomedicine at Washington University
...ns, or surgeries with a simple injection. The tiny spheres can travel through the bloodstream deep into the body to locate and highlight tumors undetectable by typical methods. While at the tumor site, the nanoparticles can deliver therapeutic agents to destroy the tumor. To advance this promising technology...Modifications render carbon nanotubes nontoxic
...e atom thick. They are related to buckyballs, tiny spheres of pure carbon that are about the same diameter. In previous studies with buckyballs, CBEN found that even minor surface modifications could dramatically reduce cytotoxicity. The nanotube study found similar results. In both cases, the researchers id...Disease-causing protein protects against nerve damage in Parkinson's disease
...bind to the membranes of synaptic vesicles ? small spheres that contain the nerve cell's neurotransmitters, chemicals that carry signals between brain cells ? indicating that they both act at the vesicles' surface. "There's a pathway, but we don't really know all the players in this pathway," Dr. Chandra sa...Hi ho silver! FSU physicist helps discover an atomic oddity
...eutrons in the silver had deformed the nuclei from spheres into fat cigar shapes. In some cases the proton pairs jumped out from the same end of the cigar, at other times from opposite ends, but they were always perfectly synchronized, Tabor said. "It's like there's a captain on board telling them exactly wh...Mathematics in fact and fiction discussed at AAAS Annual Meeting
...1 about the most efficient way to pack equal-sized spheres into a crate of given size. Would it be the staggered layers used by grocers to stack oranges for display or some other arrangement. The problem is considered by mathematicians in terms of the density of the packing rather than the total number of sp...Rice University researchers create 'nanorice'
...roperties of the two most optically useful shapes spheres and rods. It's just a coincidence that that shape turned out to look exactly like a grain of rice." Nanoparticles like nanorice can be used to focus light on small regions of space. Rice's scientists plan to capitalize on this by attaching grains of ...Chemist wins national award for contributions in medicinal chemistry
... form of recognition for our joint efforts in both spheres of life," said Anderson, who currently serves on the boards of directors of several companies and the Chemical Heritage Foundation. He was recently elected to the Board of Trustees of the Gordon Research Conferences. At Merck & Co., Anderson and cowo...Cellular scale drug delivery from the inside out
...nanospheres that makes drug delivery possible. The spheres have thousands of parallel channels running completely through them. Through capillary action, the spheres can soak up molecules of the drug to be delivered. When the channels are filled, the ends of channel...MIT research links cancer, inflammatory disease
...ed the big picture, uncovering connections between spheres of biology previously believed to be distinct. "We are finding that things that once appeared to be biologically independent are closely connected," Sorger said. "We are not just collections of independent parts."...Scientists discover a genetic code for organizing DNA within the nucleus
... protein scaffolding in the cell nucleus into tiny spheres called nucleosomes. The bead-like nucleosomes are strung along the entire chromosome, which is itself folded and packaged to fit into the nucleus. What determines how, when and where a nucleosome will be positioned along the DNA sequence? Dr. Eran Se...