Mechanism discovered for muscle wasting seen in diabetes, AIDS and other diseases
...uring disuse, such as when a limb is casted, or in spinal cord injuries. Inhibition of NF-kB in MISR mice was accompanied by a partial remission of denervation-induced muscle atrophy, including increased muscle mass and fiber size. Muscle wasting is a significant problem for patients with certain forms of...UCSD medical researchers use brain cell transplants to correct muscle spasms after aneurysm surgery
...ed involuntary muscle spasms in rats with ischemic spinal cord injury, according to research published onlin...nia, San Diego (UCSD) School of Medicine. Ischemic spinal cord injury, caused by reduced blood flow to the spinal cord, occurs in 20 to 40 percent of the seve...Other highlights in the October 20 JNCI
...ethotrexate An injection of methotrexate into the spinal fluid is used in some cancers to prevent the sprea... of tumors to the tissues that cover the brain and spinal cord. The bacterial enzyme carboxypeptidase G 2 is effective for treating rare but potentially fata...Leading scientists to discuss research applications for therapeutic cloning
...heimer's disease, heart disease, stroke, diabetes, spinal cord injuries and genetic diseases. While the hopes are real, scientific findings remain ambiguous concerning actual benefits for patients using stem cells for therapeutic purposes. "Will therapeutic cloning create immune matching? It's unclear. At t...Gene therapy approach reverses diabetic neuropathy in animal model, Pitt study finds
...touch, pain, temperature and joint position to the spinal cord, which in turn transmits the information to the brain in order to register a particular sensation. As such, to deliver the HSV vectors encoded with the neurotrophic factor genes for NGF or NT-3, the researchers inoculated an area just under the ...Stimulating nerve cells with laser precision
...optic threads that runs directly from the brain or spinal cord to a prosthetic arm or leg, creating the ultimate man-machine interface....Warning from new SLU research: Usual test for vitamin deficiency can mislead doctors
...ssociated with dementia, peripheral neuropathy and spinal cord disease," says Florian Thomas, M.D., Ph.D., a...s oxide and devastating neurological damage to the spinal cord and peripheral nerves. The link to nitrous oxide was recognized and the patient recovered with ...Sick kids researchers unmask the potential of stem cells found in adult skin
...sess for the development of possible therapies for spinal cord injury and nervous system disorders. This research is reported in the November issue of the scientific journal Nature. "We think these stem cells are actually embryonic cells that go out into the skin during development and then stay in reservoi...Researchers grow sperm stem cells in laboratory cultures
...acement tissue might be used to help patients with spinal cord injury, or disorders like Parkinson's disease or heart disease. To conduct their study, Dr. Kubota and his colleagues began with mice that had been genetically altered to express green fluorescent protein, or GFP, which gives off a green light...NJIT stem cell researcher to receive research award from biomedical group
...stem cell research to help patients suffering from spinal cord injuries and related diseases, will receive an Outstanding Women in Research Award from The New Jersey Association for Biomedical Research (NJABR), Union. Arinzeh, of Jersey City, is one of 12 women scientists who will receive research awards du...How receptors govern inflammatory pain
...cording to Hartmann and her colleagues, studies of spinal cord tissue showed that AMPA receptors are found in spinal cord regions known to be responsible for pain sensing, or nociception. However, they said, there had...A 'repulsive' protein guides blood vessel development
...ontribute to the development of connections in the spinal cord. Ginty and his colleagues plan to explore the role of the proteins in neural development, as well as whether the combination is involved in vascular patterning in the limbs....Invasive sea squirt alive and well on Georges Bank
...are tunicates, a type of sea life with a primitive spinal cord and a firm, flexible outer covering called a "tunic," from which the name derives. A filter-feeding species of the genus Didemnum, they form dense mats, made of thousands of individuals, by attaching to firm substrates such as gravel, sea scallo...UCI researchers use human embryonic stem cells to aid spinal cord injury repair
...otentially important implications for treatment of spinal cord injury and multiple sclerosis. Researchers at...The researchers then injected these cells into the spinal cords of mice genetically engineered to have no myelin tissue. After transplantation into mice, the ...Pain reliever may help treat life-threatening childhood disease
...years ago may point the way to a new treatment for spinal muscular atrophy, or SMA, a muscle-wasting and oft...or neurons nerve cells that send signals from the spinal cord to muscles throughout the body rapidly deteriorate in SMA due to reduced levels of survival mo...Columbia researchers identify drug as therapeutic candidate for spinal muscular atrophy
...e production of a protein lacking in patients with spinal muscular atrophy (SMA), a fatal pediatric genetic ...ts mechanism of action, to deliver the drug to the spinal cord, and toxicity testing of related drug molecules. A clinical trial for its effectiveness in trea...Promising results in the battle against incurable ALS muscle disease
...the fluid that circulates around the brain and the spinal cord) was quite effective. New hope for patients Furthermore, this technique permits a patient-oriented approach by enabling the administered dose of the VEGF protein to be easily controlled. Ten years ago, treatment with other proteins...Citrus shows promise for certain childhood cancer
..., and is usually a solid tumor in the neck, chest, spinal cord or adrenal gland. The finding in citrus is promising not only for its potential to arrest cancer, but because limonoids induce no side affects, according to Dr. Ed Harris, Experiment Station biochemist who collaborated on the study with Dr. Bhim...Purdue research offers hope for canine, human spinal injuries
... LAFAYETTE, Ind. - A successful method for healing spinal injuries in dogs has been developed by Purdue Univ... (PEG), if administered within 72 hours of serious spinal injury, can prevent most dogs from suffering permanent spinal damage. Even when the spine is initial......ic lateral sclerosis (ALS), heart disease, stroke, spinal cord injury and genetic diseases. Scientists believe that embryonic stem cells may have the most versatility in potential cell-based treatments, but intensive research continues on both embryonic and adult-derived stem cells. Dr. Schatten and his col...