Molecular 'on/off switch' controls immune defenses against viruses
...its shape and sends signals to other proteins that spur production of interferon, a molecule that stops vi...d drugs that could mimic viral effects on RIG-I to spur antiviral response or, conversely, mimic viral effects on LGP2 to shut down RIG-I activity. RIG-I sh...Joslin-led study uncovers role of appetite hormone MCH in insulin production
...tion of insulin. This finding has the potential to spur the development of new treatments for diabetes that stimulate the production of insulin-producing beta cells in the pancreas. This latest research, conducted with researchers at Beth Israel Deaconess Medical Center in Boston and other institutions, w...'Bridge' protein spurs deadliest stages of breast cancer
..." interactions between other cellular proteins may spur metastasis in breast cancer, the diseases deadliest stage, a study from Burnham Institute for Medical Research has found. Led by professor Gen-Sheng Feng, Ph.D., and colleagues at Burnham and Royal Victoria Hospital in Montreal, Quebec, the study ra...UCLA study uncovers clues for why Graves' disease attacks the eyes
...lls, causing a cascade of autoimmune problems that spur the body to attack its own tissue. "We think that the extra receptors allow the new antibody and IGF-1 to disrupt the programming of the T-cells," said principal investigator Dr. Terry Smith, professor of medicine at the David Geffen School of Medi...UA researchers identify new adherence factor, Pili, produced by tuberculosis
...my of Sciences, Volume 104, March 5-9, 2007, could spur further scientific investigations on TB, which is the No. 1 cause of bacterial infectious disease in the world today. Worldwide, 3 million people die each year from tuberculosis and an estimated 1.2 billion are infected with the bacteria. Virulenc...AEA, UAlbany College of Nanoscale Science and Engineering to partner on CIRCA 07
...y-enabled platforms that will drive innovation and spur commercial opportunities in a broad array of industries, including nanoelectronics, health care, energy, defense and aerospace, among others. The Convergence of International Research and Commercialization in Albany, or CIRCA '07, will be held May...MIT device draws cells close -- but not too close -- together
...o rearrange cells over time to learn which signals spur change and which don't. In the past, researchers erected chemical "moats" around cells in an attempt to keep them close but separate. Over time, however, cells invariably breech the divide. "They are very good at crossing the moat," said Bhatia, w...Heart failure: Intervention possibilities from imaging programmed cell loss
... Failure." He anticipates that this research would spur development of new drugs for heart disease....... myopathy or muscle damage. Capecchi says that may spur research to learn if SYT-SSX genes play a role in any of the numerous forms of myopathy. The researchers discovered that when the SYT-SSX2 fusion gene was expressed or activated in myoblasts, the cells became cancerous 100 percent of the time. Myo...Deactivating protein may protect nerve fibers in MS
...y drugs, which reduce the inflammation believed to spur certain T-cells in the body to attack myelin, the fatty sheath insulating nerve fibers in the brain and spinal cord. The fibers can't conduct impulses, leading to paralysis, memory loss, dizziness, fatigue, pain and imbalance. Over time, the nerve fi...Prize winners announced at ISN's World Congress of Nephrology
...coming years, "We are committed to finding ways to spur interest and investment in finding a solution to this disease I think it is entirely reasonable that in forthcoming years we will see breakthroughs in research and treatment."...Fat screen delivers plant-derived chemical with antidiabetic effects
...at, it may deposit in other tissues," where it can spur disease. Despite their efficacy, the development and clinical use of TZDs is limited by adverse effects such as fluid retention, weight gain, congestive heart failure, liver toxicity, and potential cancer risks, the researchers said. Therefore, alt...Creation of an international industrial chair in life cycle assessment
...IFE CYCLE ECONOMY "The work of the LCA Chair will spur and support voluntary corporate actions towards sustainable production and consumption, explains co-chairholder, Rjean Samson. "The Chair will provide additional tools to reduce the potential environmental impacts of corporate products and services, ...Malaria and Epstein-Barr virus linked to pediatric cancer in Africa
...fied CIDRla as the first microbial protein able to spur a latently EBV-infected cell into active production. Their results suggest that P. falciparum-derived proteins can lead to a direct reactivation of EBV during acute malaria infection, increasing the risk of Burkitt lymphoma development for children ...Columbine flowers develop long nectar spurs in response to pollinators
.... They found that most of the columbines' nectar spur length evolution happened during shifts in pollinators from bumblebees to hummingbirds, and from hummingbirds to hawkmoths. In between these shifts, evolution of the columbines' nectar spurs came to a halt. Whittall and Hodges' work provides eviden...Genetic defect links respiratory disease and congenital heart disease
..., issue of the journal Circulation. "This should spur physicians treating patients with congenital heart disease to be more vigilant about testing for and treating respiratory defects," said Dr. Michael R. Knowles, professor of pulmonary and critical care medicine and study senior author. "It is critica...Human activities increasing carbon sequestration in forests
...cent of the amount used by a farmer each year - to spur net carbon uptake by forests and actually offset a significant amount of greenhouse gases into the atmosphere. This broad study analyzed the carbon balance across a network of forest sites that represent nitrogen deposition in most of Western Europ...Screening approach leads to discovery of gene linked to breast cancer
...sustain a sizable percentage of breast cancers may spur the development of new treatments for the disease, Hahn remarks. Drugs able to target the oncogene and shut it down could offer an effective therapy for women whose tumor cells harbor the mutation. The three-stage approach to finding breast cancer ...Researchers find gene that spurs development of the epididymis
...ne works with other regionally specific factors to spur the development of structures such as the prostate gland or seminal vesicles. Inhibin beta A is the first such factor shown to contribute to epididymal coiling, he said. The identification of inhibin beta A in the development of the epididymis is i...... one of the studys authors. This study will likely spur further research into the connection between these seemingly separate conditions. Another region harbors a gene called the IL-7 receptor, which helps to control the activity of a class of immune cells called regulatory T cells. Two papers appeari...