Weizmann Institute scientists discover a control mechanism for metastasis
...s itself to the cell membrane. This action is what stabilizes the cells structure. The protein that increases, on the other hand, is made up of one short arm that only attaches to the anchor point on the cell membrane. Rather than structural support, this protein acts as a kind of plug, blocking the anchor poin...Serica scientists win AOSSM Award for ACL (knee) tissue regeneration in preclinical study
...y support structure that replaces the torn ACL and stabilizes the knee joint. This study provides the first evidence of sustainable ACL tissue engineering, said Gregory H. Altman, PhD, President and CEO, Serica Technologies, and senior author of the paper. Through advances in biomedical engineering, we now...Cannibalism of the young allows individual fish to specialize
... effect of early cannibalism is twofold. First, it stabilizes the variation in the number of individuals over time, which in turn increases the benefit of specializing on any resource since the risk of being dependent on a vanishing resource decreases. Second, an early disappearance of small newborn individuals...Shoulder ligament a linchpin in the evolution of flight
...arned that a single ligament at the shoulder joint stabilizes the wings of birds during flight. In an advanced online publication of Nature, they explain how this tough bit of tissue evolved to become a linchpin for today's fliers. "How animals got off the ground how limbs became wings is a fascinating quest...Ohio University researchers discover evolutionary oddity in flamingos
...pporting the floor of the mouth. "We suspect this stabilizes the mouth and tongue and helps with the peculiar way that flamingos eat," he said. "It's an important new piece of the puzzle of flamingo feeding--frankly, a piece we hadn't known was missing!"......ng its spatial structure, a D-amino acid component stabilizes one preferred conformation of the ring. The peptide "presents" its functional groups of atoms in a predictable three-dimensional arrangement that is further determined by the position of the D-amino acid. The amino acid L-proline has a similar stabil...Biodiversity key to sustainable biofuel according to University of Minn. researcher's findings
...ists have debated the hypothesis that biodiversity stabilizes ecosystems. The University of Minnesota study is the first to provide enough data -- gathered over a sufficient time period in an experiment that controlled biodiversity to confirm the theory. The time period of the study allowed researchers to eval...Ecosystems with many plant species produce more and survive threats better
...-year scientific debate about whether biodiversity stabilizes ecosystems. The findings, published in this week's issue of the journal Nature, are the result of 12 years of experiments conducted by David Tilman, an ecologist at the University of Minnesota, and colleagues Peter Reich of the University of Minnesot...Discoveries should aid research into cause of ALS
...ide linkage -- a bond within an SOD1 molecule that stabilizes the structure. Intermolecular disulfide bonds, or cross-links, are incorrect bonds that form between, not within, SOD1 molecules. "A year ago we demonstrated that ALS mutations have the greatest effect on the most immature form of the SOD1 protein, ...Seagrass is in decline worldwide, says UNH researcher
... root and rhizome system of these flowering plants stabilizes sediments, protecting the coastline from currents and weather-related erosion. Seagrass is an effective filter of nutrients and particulates, and it is the basis of a detrital food chain that feeds fish and shellfish. When seagrass beds disappear, Sh...Oncologists could gain therapeutic advantage by targeting telomere protein
... instead, according to Pandita,. "We saw that Rad9 stabilizes telomeres, and because we aren't yet sure how it does it, we will continue to study how Rad9 influences the telomere structure," Pandita says. "We speculate that without Rad9, some of the other proteins associated with the telomeric structure become ...VCU study shows Levitra may protect the heart
... by inhibiting PDE-5. Vardenafil, like sildenafil, stabilizes the mitochondria and protects against damage of the heart by opening the mitochondrial KATP channels in cardiac cells. Mitochondria are cellular organelles critical for converting oxygen into ATP, the key fuel for cellular function. "This study prov...JCI table of contents: December 22, 2005
...e surrounding extracellular matrix that physically stabilizes the plaque, and consequently induced plaque rupture. MMP-9 and factors that regulate its activation may be potential therapeutic targets for stabilizing rupture-prone plaques. TITLE : Macrophage expression of active MMP-9 induces acute plaque disrup...JCI table of contents December, 2005
... that stabilizing mitochondrial membrane potential stabilizes the cellular action potential (AP), blunts AP shortening during ischemia, and prevents ventricular arrhythmias during reperfusion. This work could explain ischemia-related arrhythmias and explores the therapeutic potential of a compound targeting th...New target found to fight, treat Parkinson's
... off the treatment by adding the drug taxol, which stabilizes microtubules and prevents their breakdown. Findings showed that by protecting microtubules, the toxic effect of rotenone on dopamine-producing neurons was greatly reduced. "Based on these findings, we believe that microtubules are a critical target...Researchers find molecule that inhibits regrowth of spinal nerve cells
...of myelin a substance that normally insulates and stabilizes long nerve fibers in adult vertebrates chemically blocks the ability of nerve cells to grow through myelin that is released when the spinal cord is damaged.While other myelin components also block nerve growth, a component called ephrin-B3 inhibits ...JCI table of contents July 1, 2005
...s cells to the vessels, facilitates branching, and stabilizes the new vasculature. These data have broad implications for the areas of vascular biology, cancer biology, and regenerative medicine. TITLE: NO mediates mural cell recruitment and vessel morphogenesis in murine melanomas and tissue-engineered blood v...VCU research shows Viagra prevents anti-cancer drug induced heart damage
...icine, physiology and biochemistry at VCU. "Viagra stabilizes the mitochondria and protects against free-radical damage of the mitochondria and heart dysfunction caused by treatment with DOX by opening the mitochondrial KATP channels in cardiac cells," said Kukreja. Mitochondria are cellular organelles critical...Key mechanism in genetic inheritance during cell division identified
...this ring formation promotes microtubule assembly, stabilizes against disassembly, and promotes bundling," says Eva Nogales, a biophysicist who holds joint appointments with the Lawrence Berkeley National Laboratory (Berkeley Lab), the University of California at Berkeley, and the Howard Hughes Medical Institut...Endurance running may be key to evolution of human body form
...odest gluteus maximus. "Your gluteus maximus stabilizes your trunk as you lean forward in a run," Lieberman says. "A run is like a controlled fall, and the buttocks help to control it." Runners also get a lot of help from their Achilles tendons, tough bands of tissue that anchor the calf muscles ...