Purdue-IU researchers explore new method for early disease diagnosis
...insight into the metabolites present, however this standard approach has disadvantages, Raftery said. The sign...n this case a carbon atom that is heavier than the standard carbon atom. Because we can easily detect this isotope, it causes these tagged metabolites to effect...Researchers discover gene responsible for Restless Legs Syndrome
... is exceedingly common but not taught as a part of standard medical education, in part leading many medical professionals, educators and academicians to challenge its commonality and authenticity....Jefferson scientist's patent dramatically improves
...s have been the wrong choice, he says, because the standard method is more expensive and takes longer. This solution that we found is literally a better, faster way of doing it. According to Dr. Brody, the patent hinges on the pairs finding, through trial and error, that the compound lithium boric acid in D...Losing weight after pregnancy -- diet and exercise better than diet alone
... not lose significantly more than women who have a standard post-natal lifestyle. However, women who combined exercise and dieting did lose more weight than those with normal care. Returning to body weight gradually after giving birth seems to be important, because women who regain their pre-pregnancy weigh...Malaria -- Effective insecticide-repellent synergy against mosquito vectors
...the organophosphate family, combined with either a standard repellent, DEET, or with a new-generation syntheti...ly the association between the insecticide and the standard repellent produced a synergistic effect that inhibited the mosquito from taking its blood feed. A sy...Serica scientists win AOSSM Award for ACL (knee) tissue regeneration in preclinical study
...de from natural silk protein, is installed using a standard surgical procedure to repair a torn ACL and is des...iomechanical support structure, implanted during a standard surgical procedure, which supports the development of functional ACL tissue, thereby avoiding the li...Nodal status is best predictor of outcome after neoadjuvant therapy for esophageal cancer
...table size and location. The patients were given a standard protocol of radiation therapy and concurrent chemotherapy with fluorouracil and cisplatin before undergoing thoracotomy with lympadenoctomy and nodal dissection; the extent of surgery and lymph node dissection depended on the exact location of the tu...Macrochem acquires option to license pexiganan
...atment and will undergo efficacy assessments using standard criteria of nail appearance and mycology. However, the Company will collect and evaluate 24-week interim data later this year. This trial was specifically designed, with the assistance of well-known onychomycosis experts, to address three important o...News tips from the Journal of Neuroscience
...ice rendered epileptic by pilocarpine treatment, a standard animal model of temporal lobe epilepsy. Postembedding immunogold labeling confirmed a perisynaptic decrease in the subunit in dentate granule cell dendrites within the molecular layer. However, physiological studies found that tonic inhibition was s...Scientists identify 2 distinct Parkinson's networks
...ponse to treatments. The study also shows that the standard drugs used to treat Parkinsons alter the areas that are involved in movement but not those that regulate cognition. The network that grows abnormal over time includes an called the pre-frontal cortex, known as the brains executive secretary; organizi...Gene's activity points to more lethal subtype of AML
...han are patients with low ERG expression following standard therapy. The Cancer and Leukemia Group B study ...atients with low ERG activity can be treated using standard therapy. The research confirms a 2005 study led by the same Ohio State researchers in a completel...Chronic fatigue -- clues in the blood
...tudies, like this, said Professor Lloyd. It sets a standard for highly sophisticated, comprehensive gene expression studies in the blood of all sorts of human diseases from rheumatoid arthritis and multiple sclerosis through to schizophrenia....Researchers discover method for identifying how cancer evades the immune system
...e researchers believe such analysis could become a standard practice in cancer diagnosis and treatment. The implication is that once you know the mechanism by which tumors evade the immune system, you can match that tumor to available therapies, said senior author Alan L.Epstein, M.D., Ph.D., professor of P...Cell receptor may lead to new 'biomarker' for pancreatic cancer
...d antibodies killed more cancer cells than did the standard treatment drug gemcitabine (gem-SITE-uh-bean) alon...ing antibodies that block the RON receptor and the standard chemotherapy drugs might stop progression of pancreatic cancer more effectively, says Waltz. RON cou...Researchers find gene that spurs development of the epididymis
...ewski had found, the epididymis did not follow the standard path, even though testosterone production was normal. From his earlier work, Yao knew that the gene for one component of a growth factor, inhibin beta A, is highly expressed in the part of the Wolffian duct that eventually becomes the epididymis. H...Other highlights in JNCI, June 26
...tudies. Overall survival is considered the gold standard endpoint for cancer treatment trials. But the time and money required to conduct a trial using overall survival as the endpoint has led researchers to consider other endpoints that can act as surrogates for overall survival. Looking at 52 studies ...MIT tool determines landslide risk in tropics
...eight and certain structural requirements that are standard for the entire country," said Saldivar-Sali. "But in an area with a 66 hazard rating, which is relatively high on a scale that goes up to 99, should the building code be more stringent or be zoned for no building at all"" Saldivar-Sali stresses the...Gut check: Tracking the ecosystem within us
...ed using their microarray with the laborious gold standard approach of using genetic libraries of bacteria to get a snapshot of the microbial ecosystem in an infant at a given point in time and found that their new method performed very well. The results, said Palmer, were striking: the group found that th...St. Jude shows gene test not needed if cancer drug given in low doses
...e drug in small doses for two weeks instead of the standard single large dose once a month, children can begin treatment with irinotecan immediately. Irinotecan is used to treat childhood solid tumors such as neuroblastoma, sarcomas and kidney tumors. A report on this study is in the June 20 issue of the Jo...Dietary calcium is better than supplements at protecting bone health
...is known to maintain bone mineral density. But the standard form of estrogen is broken down or metabolized in the liver to other forms - some active and some inactive. Urinalysis showed that women in the "diet group" and the "diet plus supplement group" had a higher ratio of active to inactive estrogen metabo...