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Common treatment for methamphetamine overdose may damage brain cells

...aboratory animals raises immediate concerns that a standard treatment for methamphetamine overdose in humans might worsen drug abuse-related brain injuries," says William Carlezon, PhD, at Harvard's McLean Hospital, who was not affiliated with the study. "A crucial next step is to determine how atypical antip...

Rapid syphilis testing in Haiti will prevent congenital disease and stillbirths

...egnant women for syphilis. The first strategy, the standard of care in rural Haitian areas without access to s... if symptoms are found. The second, considered the standard in urban areas, is a blood test for antibody response to the syphilis bacterium -- an approach that ...

Jefferson scientists use gene therapy to reverse heart failure in animals

...d "unique and additive effects" to currently used, standard heart failure drugs called beta-blockers. Reporting in the American Heart Association journal Circulation, researchers led by Walter J. Koch, Ph.D., director of the Center for Translational Medicine and the George Zallie and Family Laboratory for C...

Flaws in colonoscopies may increase risk of colon cancer

...23, 2007) -- Colonoscopies are considered the gold standard for detecting colon cancer, the second leading cau... significantly improved and reached the competency standard after 150 procedures (71.5, 82.6, 91.3, 94.4, 98.4 and 98.7%, respectively, for every 50 procedures)...

Long-term ulcerative colitis study shows Remicade responders maintained improvement

...were unresponsive to or intolerant to at least one standard therapy, including corticosteroids, immunosuppressants or 5ASAs, were enrolled in ACT 1 (n=364) or ACT 2 (n=364). The 728 patients were randomized to receive REMICADE 5 mg/kg, REMICADE 10 mg/kg or placebo at weeks 0, 2, 6 and every subsequent 8 weeks...

Einstein researchers' discover 'radiation-eating' fungi

...forming units and dry weight) than when exposed to standard background radiation. The researchers also carried out physico-chemical studies into melanin's ability to capture radiation. By measuring the electron spin resonance signal after melanin was exposed to ionizing radiation, they showed that radiation...

Exercise reverses aging in human skeletal muscle

...cle. The six month resistance training was done on standard gym equipment. The twice-weekly sessions ran an hour in length and involved 30 contractions of each muscle group involved, similar to training sessions available at most fitness centers. The strength test was based on knee flexion. The older par...

Study focuses on only carnivore with 'fingerprints'

...made up of patterns of dots rather than ridges, so standard criminology software did not work. "We tried submitting fisher prints to the state's fingerprint database but it didn't pair up the prints well," says Richard Higgins, retired chief of the DCJS Bureau of Criminal Identification. "But looking at them...

Tropical birds have slow pace of life compared to northern species, study finds

.... To measure BMR and PMR, the researchers used a standard test in which they placed the birds in airtight steel containers with airflow in and out carefully controlled and monitored. The birds were allowed to get accustomed to the container, and then the researchers measured their oxygen consumption, which ...

Chemotherapy drug shrinks brain tumors

...mparing temozolomide to radiotherapy, which is the standard treatment for such brain tumors, isn't easy and he says that's why continued research into comparing the two treatments is needed....

New techniques redefine assessment of liver disease

...Study (Abstract #3) While a liver biopsy is the standard method of diagnosis and disease progression for non-alcoholic steatohepatitis (NASH), the most extreme form of nonalcoholic fatty liver disease (NAFLD), researchers previously demonstrated that a less invasive blood test to determine caspase three-ge...

Spotlight on liver disease: Improving today's treatments

...00 g/kg rFVlla or 300 g/kg rFVlla. In addition to standard treatment, study participants were given the first... as a treatment option did not improve efficacy of standard treatment, the treatment-related failures were lower than expected. While there was no significant ...

Computer model maps efficient inoculation of hospital staff in pandemic outbreak

...al College. Using discrete-event simulation -- a standard technique in operations research -- researchers compared two staff-management strategies with specific rules for dispensation and an unmanaged scenario in which staff would line-up for inoculation all at once or at the time of their choosing. In the ...

Combining NSAIDs with chemotherapy, radiation may improve cancer treatment

...ter suited to treating cancer, in combination with standard therapies, rather than preventing it, according to... phase is particularly exciting because one of the standard therapies for most cancers -- chemotherapy -- often has its maximal effect at that stage of the cell...

Growing nerve cells in 3-D dramatically affects gene expression

...genes differently compared to nerve cells grown in standard two-dimensional petri dishes. The study, publish...nt environments. They placed one batch of cells in standard petri dishes coated with collagen. They suspended the other batch in a thicker collagen gel. The bio...

Iowa State scientists demonstrate first use of nanotechnology to enter plant cells

...abling their delivery into the plant cell with the standard gene gun. The biologists successfully used the technology to introduce DNA and chemicals to Arabidopsis, tobacco and corn plants. "The most tremendous advantage is that you can deliver several things into a plant cell at the same time and relea...

Gene thought to assist chemo may help cancer thrive

...ing or not in the chemotherapy-treated tumors. A standard belief in cancer research is that a working p53 is essential in helping chemo patients because it turns on the killing mechanism for the cells that were damaged by chemo. But McDonald points out that p53 can also help repair damaged cells. If p53 is ...

DOE JGI sets 'gold standard' for metagenomic data analysis

...te fool's gold from the real nuggets. Such a gold standard has now been provided through work led by the U.S. Department of Energy Joint Genome Institute (DOE JGI) with colleagues from Oak Ridge National Laboratory and IBM's T.J. Watson Research Center. Their results are published in the May edition of Natur...

The 'driving' force behind electric vehicles

...mparison shows that individual cultures still have standard operating procedures which reflect deep-rooted national political and social cultures despite increasing globalization. It also suggests that governments should take into account the cultural dimension when promoting policy change. ...

Medical research scientists make ethical value judgments in research

...om additional genetic research are already part of standard medical practice, or if the new drugs resulting from genetic research would likely be too expensive for minority groups, then genetic research may not be the most effective way of trying to decrease racial health disparities," notes Dr. de Melo-Martn...

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(Date:11/25/2009)...you eat may be just as vital to your health as wha... for Biological Studies. Their experiments in mice...sands of genes in the liverthe body,s metabolic cl... not by the body,s circadian clock as conventional...he activity of a large number of genes completely ...
(Date:11/24/2009)...pening new doors to understanding how sounds assoc...a marine mammal or if they hear it at all. , Th...rs that NASA uses to detect flaws in the space shu... scientists to peek inside the giant head of a wha...onal replicas of a whale,s hearing anatomy using a...
(Date:11/24/2009)...tion of a remarkable class of ring-shaped protein ...Lawrence Berkeley National Laboratory (Berkeley La...y beamline at the Advanced Light Source (ALS). The...ssion and replication, and are vital to the surviv...agents, such as the human papillomavirus, which ha...
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