Small molecule offers big hope against cancer
...d to normal cells, as well as protection from many standard chemotherapies. Because mitochondria regulate cell death--or apoptosis--cancer cells can thus achieve resistance to apoptosis, and this appears to be reversed by DCA." "One of the really exciting things about this compound is that it might be able t...New proteomic method to detect inflammation in amniotic fluid
...opulations will be needed before it could become a standard procedure in the clinic....ACS News Service Weekly PressPac -- January 10, 2007
... drug dose Molecular Pharmaceutics Why does the standard dose of certain medications prove dangerously high for some patients and too low to produce beneficial effects in others? Scientists have added a previously unrecognized factor to the list of explanations (such as age, gender, diet and genetics) for ...Prenatal cocaine's lasting cellular effects
...eficit hyperactivity disorder (ADHD). However, the standard treatments for ADHD -- Ritalin and other stimulants -- are not always effective in these children. Studying the effects of prenatal cocaine exposure on the developing brain is difficult in human populations because cocaine abusers often abuse othe...TIGR researchers reveal tricks of common sexually transmitted infection
...d bedding and towels, and even toilet seats. The standard treatment for trich is Flagyl, but the single-celled parasite that causes the disease, Trichomonas vaginalis, is becoming increasingly resistant to this drug, making development of new medicines a high priority. Infected men frequently have no symp...Researchers urge monitoring of bone health during chemotherapy
...ve a longer disease-free period than those getting standard dosing without G-CSF. "It's possible that women on G-CSF-supported chemotherapy could do even better if we paid more attention to skeletal health," says lead author Angela Hirbe, an M.D./Ph.D. student in Weilbaecher's lab. "Strengthening the skeleto...Blood test predicts cardiac events and death in heart patients
...ething that we are otherwise unable to detect with standard tests such as echocardiography," says principal investigator Mary Whooley, MD, a staff physician at SFVAMC and an associate professor of medicine at the University of California, San Francisco. The study appears in the January 10, 2007 issue of Jour...Reduced frontal-lobe activity and impulsivity may be linked to alcoholism risk
... City area. All participants were assessed with a standard visual oddball task, where the subject presses a button only to rarely occurring target stimuli (the letter "X") embedded in a series of frequent non-target stimuli. Meanwhile, brain waves or event-related potentials (ERPs) were recorded with a non-...'PET/CT in Cancer Patient Management' examined in Journal of Nuclear Medicine Supplement
...graphy (PET) and computed tomography (CT) scans as standard imaging tools to pinpoint disease states in the body. When PET is used to image cancer, a radiopharmaceutical (such as fluorodeoxyglucose or FDG, which includes both a sugar and a radionuclide) is injected into a patient. Cancer cells metabolize suga...Two studies: Speeding development of novel tracer for prostate cancer
...T) and PET with computed tomography (PET/CT), both standard imaging tools that can be used to pinpoint diseases in the body. When PET is used to image cancer, a radiotracer is injected into a patient, and it is drawn in higher concentrations to cancerous areas. The highly sensitive PET scan picks up the metab...Study identifies glucose 'sensor' that plays dual role in glucose metabolism and fat synthesis
...d because the carbohydrate does not conform to the standard definition of a typical ligand that activates nuclear receptors, transcription factors that coordinate gene expression in response to hormonal and environmental signals. This discovery, Saez said, represents the first signaling pathway where a carboh...Gene tied to longevity also preserves ability to think clearly
...e as likely to have good brain function based on a standard test of cognitive function. Later the researchers validated their findings independently in a younger group of 124 Ashkenazi Jews between the ages of 75 and 85 who were enrolled in the Einstein Aging Study led by Dr. Richard Lipton. Within this gr......imps. But they do illustrate there isn't a single, standard estimate of variation that incorporates all the ways humans, chimps and other animals can be genetically different from each other. Any measure of genetic difference between humans and chimps must therefore incorporate both variation at the nucleotid...Shotgun sequencing finds nanoorganisms
...small organisms we didn't know how to culture with standard techniques. This shows the great promise of shotgun sequencing to profile a community of organisms without making any assumptions about what is there." Nearly three years ago, Banfield employed shotgun sequencing to pick out the half-dozen bacteria...On the golf tee or pitcher's mound, brain dooms motion to inconsistency
...ice makes perfect"" If complete consistency is the standard of perfection, then it seems that nobody will ever be perfect....Human-chimp difference may be bigger
...pends on what you're asking. There isn't a single, standard estimate of variation that incorporates all the ways humans, chimps and other animals can be genetically different from each other." By studying "gene families" -- sets of genes in every organism's genome that are similar (or identical) because the...Durable critters providing insight for human egg preservation
...ly about 1-5 percent of eggs develop to term after standard cryopreservation techniques, which include a combination of slow freezing in conjunction with low levels of cryoprotectants such as dimethyl sulfoxide, or rapid freezing with more cryoprotectants. Dr. Eroglu says the sugars, which help protect the ...Genesearch Breast Lymph Node assay detects breast cancer metastases with greater sensitivity
... with greater overall sensitivity than the current standard of care," said study investigator Peter W. Blumencranz, MD, FACS, Medical Director of Comprehensive Breast Health and Cancer Services, Morton Plant Mease Healthcare, and Medical Director of Moffitt Morton Plant Cancer Care, Clearwater, Florida. "Thi...CellSearch System cleared for monitoring metastatic breast cancer
... metastatic breast cancer earlier than the current standard of care. The results of serial testing for CTCs w...olid tumors and enter the blood stream, and is the standard in a new class of diagnostic tools. The presence and number of CTCs in the blood provides valuable ......n of the USC Neuroscience Institute, author of the standard printed rat brain atlas, Brain Maps, Structure of...g a JavaScript program converting the files into a standard vector graphic (SVG) format. The SVG images are stored on the users system and organized using the s...