Disorderly protein brings order to cell division
...prematurely, putting cell division into overdrivea state that produces cancer. A report on the work appears in the January 25 issue of the journal Cell. The long p27 molecule drapes itself like an arm over the shoulders and down the side of CDK2, the researchers explained. The upper arm of p27 binds tig...Reactivated gene shrinks tumors
...tissues) did not undergo apoptosis but went into a state of senescence, or no growth. Those tumors took longer to shrink but the senescent tumor cells were eventually cleared away. The researchers are not sure why these two cancers are affected in different ways, but they have started trying to figure it...Advances in Optics for Biotechnology, Medicine and Surgery
...ions, the invited speakers will define the current state of the art and suggest new and promising research directions. There will be extensive formal discussion periods in each session and informal discussions will be encouraged. Sessions will include: Intrinsic contrast microscopy; Comprehensive,...Antiretroviral resistance testing in HIV infected patients improves health and saves costs
...uding patients from all University Clinics and two state hospitals in Switzerland. In this study, both health care costs and productivity costs, i.e. costs due to absence from work because of ill-health, were included in the analysis. Using most recent scientific methods, the authors could show that antire...Quantum biology -- Powerful computer models reveal key biological mechanism
... partnership between Rensselaer, IBM, and New York state to create one of the world's most powerful university-based supercomputing centers. The additional computing power will allow them to model complex biological systems with even greater accuracy: "The more atoms you include, the more accurate your s...Dual enzymatic activity of RECQ1 explained by different quaternary structures
...x is provided, including a demonstration that this state is associated with DNA strand annealing, whereas the smaller form carries out DNA unwinding. The functional switch from strand-annealing to DNA unwinding is controlled by ATP binding, which promotes the dissociation of the larger, higher-order comple...Donald H. Sebastian receives award from SMART
...s Homeland Security Technology Systems Center. The state designated this center to be New Jersey's primary homeland security consultant for technology evaluation. Sebastian oversees the development of prototypes for integrated homeland security systems for testing, demonstration and training. Sebastian...Rural America more prepared for disaster -- also more vulnerable
...d in Illinois but the total number of CERTs in the state is harder to assess. Finding this complete set of ...tive CERTs and to share lessons learned across the state and country between CERTs....Large size crucial for Amazon forest reserves
...absences from detection failures, the authors used state of the art statistical methods developed by James Nichols and colleagues, at the U.S. Geological Survey's Patuxent Wildlife Research Center. "With a handle on the detection problem it is much easier to understand real species occurrence", said Nicho...Scientists sequence genome of parasite responsible for common sexually transmitted infection
...enerally requires public health notification under state statutes. By better understanding the parasite's genetic structure, we hope to better understand how best to prevent and/or treat the infection it causes."...Scientists crack the genome of the parasite causing trichomoniasis
...s of syphilis, gonorrhea or chlamydia to local and state health authorities who report the figures to the Centers for Disease Control and Prevention. This process is not mandatory for trichomoniasis. "It is quite astonishing that this disease does not receive the attention it should," says Dr. Carlton. T...Wheat can fatally starve insect predators
...ntrolled by resistant plants. During the 1980s the state of Georgia suffered $28 million in lost wheat in one year after the fly overcame the plants' resistance gene used in the area at the time. The Hessian fly is particularly insidious because it actually can control the wheat plant's development. Th...New findings blow a decade of assumptions out of the water
...ere it is being pulled back apart into its gaseous state by a different kind of micoorganism, he says. Nitrogen gas, N2, is unusable by life. It has to be fixed, that is, latched onto other chemicals to form compounds such as nitrate, NO3. Only then can it be used to build amino acids and proteins essenti...New study sheds light on 'dark states' in DNA
...tate University have probed an unusual high-energy state produced in single nucleotides -- the building blo...ientists have been able to probe the "dark" energy state -- so called because it cannot be detected by fluorescence techniques used to study other high-energ...AAAS applauds nationwide science and math standards based on existing guidelines
... academic standards and learning goals differ from state to state, noted Shirley Malcom, director of Educat...idered to be proficient in science and math in one state may not meet expectations if the family moves across state lines. As American families become increa...ACS News Service Weekly PressPac -- Dec. 20, 2006
...ps in organic chemists' understanding of the solid state of matter, Amato writes. Those gaps are apparent at a time when pharmaceutical companies are recognizing that minuscule differences in the crystal structures of drugs can have big influences on how drugs work in patients. ARTICLE #5 EMBARGOED FOR ...A simple feedback resistor switch keeps latent HIV from awakening
... propose this requirement may avoid making the off state so easy to reach that the virus remains dormant all the time. This model also helps explain why some HIV patients experience short "blips" of viral activity, despite relatively low viral concentration. According to the authors, these pulses of viral ...Four Arnoux's Beaked Whales observed from Polarstern expedition
...Germany focuses its CCAMLR-related research on the state of fish and krill stocks in the Atlantic sector of the Southern Ocean. This research is conducted by the Seafisheries Institute of the Federal Research Centre for Fisheries in Hamburg on behalf of the Federal Ministry of Nutrition, Agriculture and Co...Dengue and other hemorrhagic fevers: Towards a first potential treatment
... causes blood loss, can lead to a fatal shock-like state (Dengue Shock Syndrome) with or without associated haemorrhage, and is currently increasing in tropical countries. The pathological mechanisms of Dengue are still unknown and it has not been possible to produce any treatment or vaccine. The only curr......es observed after the world entered an "ice-house" state about 34 million years ago. In the early half of the 20th century, Serbian physicist Milutin Milankovitch first proposed that cyclical variations in the Earth-Sun geometry can alter the Earth's climate and these changes can be discovered in the Ear...