Other highlights in the May 17 JNCI
...nd that when all statins were considered together, statin use did not affect a person's risk of invasive bre...uld assess associations with individual statins or statin categories because [statin] class differences may exist," the authors write. Contact: Jim Swyers, 41...Harvard Medical signs agreement with Merck to develop potential therapy for macular degeneration
...ements and cholesterol-lowering drugs, such as the statin class, have done for cardiovascular disease. In some cases of macular degeneration called geographic atrophy, holes appear in the macula that are surrounded by clumps of lipofuscin. "One of the worrisome issues with the lipofuscins is that they are i...U of I scientist develops enzyme inhibitor that may slow cancer growth
... inhibiting the action of an enzyme, including the statin drugs used to lower cholesterol, he added. Garrow became interested in BHMT, which is abundant in the liver and present in lesser amounts in the kidneys, because elevated levels of blood homocysteine have been linked with a number of diseases, incl...UT Southwestern scientist named Keck Foundation Distinguished Young Scholar in Medical Research
...l synthesis and the target of cholesterol-lowering statin drugs. "I'm grateful to the W.M. Keck Foundation for this support that allows young researchers to explore novel projects and take on new challenges in high-risk areas that could lead to important medical breakthroughs," he said. A native of Bosw...Nanotechnology enables low-dose treatment of atherosclerotic plaques
...rated into a protocol that includes lipid-lowering statin drugs or dietary changes."Next, the research group plans to study the effect of fumagillin nanoparticles in the treatment of cancerous tumors. According to Winter, the use of inhibitors of blood vessel growth is a well-accepted therapy for cancer, su...Key fat and cholesterol cell regulator identified, promising target
...-cholesterol (targeted by the cholesterol-lowering statin drugs). However, more effective ways to treat all of the components of metabolic syndrome are needed. One attractive approach might be to target the genetic switches that promote cholesterol and lipid synthesis, but it would require a detailed unders...JCI table of contents: September 1, 2006
...late. Treating female mice during pregnancy with a statin (a drug that decreases the production of cholesterol) reduced the level of cholesterol precursors in the fetal mice and decreased the incidence of cleft palate. This study provides enormous insight into why certain gene defects cause disability. In...Diet can provide protection against development of certain cancers, new studies show
...the AACR annual meeting in 2005, that men who used statin drugs experienced half the risk of developing adva...re continuing to examine other pathways with which statin drugs interact, such as reduction of inflammation." The researchers looked at cholesterol levels f...Other highlights in the December 20 JNCI
...ntly reported studies found an association between statin use and a reduced risk of prostate cancer. However...s. To investigate a possible association between statin use and the risk of prostate cancer and advanced prostate cancer, Elizabeth A. Platz, Sc.D., of the ...Other highlights in the January 3 JNCI
...urther understand the possible association between statin use and colorectal cancer risk, Patricia F. Coogan...chers initially found a modest association between statin use and decreased colorectal cancer risk. However, after they took into account how often people too...New study to test statin-Parkinson's link
...stry, the magazine of the SCI. Suggestions of a statin link are not new, but the results of a recent stud...han a decade. Huang's new study will examine the statin link. A total of 16000 patients for whom 20 years of baseline fasting cholesterol measurements are a...Academy honors 18 for major contributions to science
...rvey of the entire sky, the discovery of the first statin for lowering cholesterol, and insights into how th...contributions in discoveries of Mevacor, the first statin that lowers cholesterol levels, and of Vasotec and Prinivil for treating hypertension and congestive...UT Southwestern leaders to receive national award for medical research accomplishments
...tabolism. Their findings led to the development of statin drugs, the cholesterol-lowering compounds that are now among the most important widely prescribed medications in the world. Dr. Seldin, an intellectual cornerstone of UT Southwestern Medical School since the 1950s and chairman of internal medicine...Statin treatment improves spatial memory in mouse models of Alzheimer's
Treatment with Simvastatin, one of the statin drugs widely used for lowering cholesterol in huma... bred to have an Alzheimers like disease. Although statin improved memory in both males and females, the results were more pronounced in males. Dr. H. A. Mo...No evidence that widely prescribed statins protect against prostate cancer
...rmones. A large, recent study found that men using statin drugs were at lowered risk of developing metastati...d over a long period of time. But other studies on statin use and prostate cancer risk have had mixed results, according to Hall. To study a narrow questio...