News tips from the Journal of Neuroscience
...y were optimal at rostral and slightly ventral ICC stimulation sites. At least two functional regions emerged, one caudal--dorsal and one rostral--ventral, which will require consideration in designing implants. 4. Microglia, Complement, and Neuropathic Pain Robert S. Griffin, Michael Costigan, Gary J. Br...First case of successful ovarian tissue transplantation between two, nonidentical sisters
...for which her sister would have to undergo ovarian stimulation with follicle stimulating hormones and then oocyte...he tissue donor and had refused to undergo ovarian stimulation for oocyte donation. Analysis of the sisters HLA type showed that their genetically different cel...News tips from the Journal of Neuroscience
...mage hippocampal slice cultures. After theta-burst stimulation (TBS), CA1 pyramidal neurons generated new dendrit... The authors used repetitive transcranial magnetic stimulation to interfere with premotor, visual, and parietal areas during visual body processing. Disruption of ...Brain's 'hearing center' may reorganize after implant of cochlear device
...average, eight months before the study. Electrical stimulation to the ear allowed the team to locate where in the brains auditory cortex various frequencies were processed and come up with a map for these tones. Their results demonstrated that in people who had cochlear implants for at least three months, normal...MIT IDs link between brain tumor proteins
...ittle effect. This could be because the continuous stimulation of the receptor is so intense and because the receptor interacts with numerous other proteins that also promote tumor growth, said White, who is also affiliated with MITs Center for Cancer Research and its Computational and Systems Biology Initiative...UCLA researchers show that culture influences brain cells
...subjects. A procedure called transcranial magnetic stimulation (TMS) was used to measure the levels of so-called corticospinal excitability (CSE)which scientists use to probe the activity of mirror neurons. They found that the American participants demonstrated higher mirror neuron activity while observing th...Germany's embryo protection law is 'killing embryos rather than protecting them'
...ot having to go undergo repeated cycles of ovarian stimulation because enough eggs are being collected from the first cycle to freeze for use at a later date if the first cycle using the fresh eggs fails. This is much better for the health of the women. The increasing use of frozen eggs has also led to improve...First baby is born after oocytes were matured in the lab and frozen
...n, especially for patients who cannot have ovarian stimulation and all patients who do not have enough time to undergo ovarian stimulation, he said. However, we have to remember that these are only preliminary results from a small number of patients who were not cancer patients themselves. As for all methods for...Personalized approach to ovarian stimulation achieves high ART pregnancy rates
...ula that allows a personalised approach to ovarian stimulation therapy for women seeking fertility treatment. Clinical tests demonstrated that when clinicians used the formula (or algorithm) to calculate the best starting dose for each patient, both the number of oocytes retrieved and pregnancy rates rose. Pro...News tips from the Journal of Neuroscience
...n columns in anesthetized cats. Single-orientation stimulation evoked GE BOLD responses throughout the brain, par...ion-nonspecific response was reduced by continuous stimulation and was further dampened using the spin-echo (SE) fMRI technique. In order to determine whether iso-...Lancet study shows gene therapy for Parkinson's disease is safe and some patients benefit
...s patients. And in the past decade, the deep brain stimulation has worked in as many as 70 percent of patients who have opted for the surgical procedure. If it doesn't work, the electrodes can be removed. (By comparison, it would be impossible to reverse gene therapy.) Gene therapy could be a more natural way t...Gene therapy study shows safety and statistically significant improvement in Parkinson's disease
...s where reducing STN activity by either electrical stimulation or lesioning can help ameliorate the symptoms of advanced Parkinsons disease. The Phase 1 study was not specifically designed to assess efficacy. Nonetheless, the researchers reported the clinical outcomes to be very encouraging, with treated patie...Human interaction and stimulation enhance chimpanzees cognitive abilities, according to new research from the Chimpanzee Cognition Center at The Ohio State University. The study (1) is the first to demonstrate that raising chimpanzees in a human cultural environment enhances their c...Studies to find better ways to preserve human eggs, ovarian tissue under way
...emotherapy, you often dont have time to go through stimulation cycles to get oocytes, says Dr. Emmi. You are concentrating on getting rid of cancer cells. Also, if a woman has breast cancer, for example, hormones needed to induce ovulation could be problematic because many breast cancer cells have estrogen recep...A living memory chip, black holes on the loose, and a clearer picture of ocean currents
...hers propose that their work implies that chemical stimulation may be crucial to learning and memory formation in living organisms. -KM Black Holes on the Loose Manuela Campanelli, Carlos O. Lousto, Yosef Zlochower, and David Merritt Physical Review Letters, forthcoming (advance copy available) Research ...News tips from the Journal of Neuroscience
...fter the authors induced L-LTP with high-frequency stimulation (HFS). Inhibitors of the extracellularly regulated kinase (ERK) pathway reduced expression. Conversely, inhibitors of phosphatidylinositide 3-kinase (PI3K), an upstream component of the mTOR pathway, reduced HFS-induced phosphorylation of ERK, sugges...Common treatment for methamphetamine overdose may damage brain cells
...ne suspect the damage results from the exaggerated stimulation of cells by the amino acid glutamate, which proves toxic to cells producing the neurotransmitter gamma-aminobutyric acid (GABA). Their results are published in the May 30 issue of The Journal of Neuroscience . "This work in laboratory animals rais...Fragile X syndrome -- A stimulating environment restores neuronal function in mice
... neurons. Importantly, they found that increased stimulation of neurons in the mice, which enhanced calcium sig...kout mice to an enriched environment caused higher stimulation that would restore normal neuronal plasticity. They gave such mice a variety of cage toys, and also ...A close-up on pancreatic disease: How do we improve the odds?
...ned the influence of EGFR/ErbB3 expression and NRG stimulation on the anti-proliferative effects of erlotinib in nine pancreatic cancer cell lines. The expression of EGFR, ErbB3 and NRG was also evaluated in 31 postoperative pancreatic cancer specimens and correlated with patient overall survival. The team ...Studies assess effectiveness of serotonin and nerve stimulants on irritable bowel syndromes
...ooking at the potential therapeutic value of nerve stimulation for constipation. DDW is the largest internationa... response and physiological effect of sacral nerve stimulation in patients with slow transit constipation and normal transit constipation with impaired evacuation....